Nutlin3 blocks vascular endothelial growth factor induction by preventing the interaction between hypoxia inducible factor 1α and Hdm2

Cancer Research

Volumn 67, Issue 2, 2007, Pages 450-454

  LaRusch, Gretchen A ^a   Jackson, Mark W ^a   Dunbar, James D ^b   Warren, Robert S ^c   Donner, David B ^c   Mayo, Lindsey D ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIGASE INHIBITOR; NUTLIN3; PROTEIN MDM2; PROTEIN P53; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CONSERVED SEQUENCE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMIDAZOLES; PIPERAZINES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MDM2; RABBITS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SEQUENCE ALIGNMENT; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33846703114     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-2710     Document Type: Article

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