Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock

Journal of Biological Chemistry

Volumn 286, Issue 37, 2011, Pages 32542-32551

  Hara, Toshiro ^a   Mimura, Kouhei ^a   Abe, Takaya ^b   Shioi, Go ^b   Seiki, Motoharu ^a   Sakamoto, Takeharu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b RIKEN Center for Biosystems Dynamics Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATP GENERATION; CYTOKINE PRODUCTION; ENERGY PRODUCTIONS; HYPOXIA-INDUCIBLE FACTOR 1; METABOLIC SHIFT; METABOLIC SYSTEMS; MUTANT MICE; OXIDATIVE PHOSPHORYLATION; PHYSIOLOGICAL FUNCTIONS; SEPTIC SHOCKS; WILD-TYPE CELLS;

GENES; MACROPHAGES; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

MAMMALS;

ADENOSINE TRIPHOSPHATE; HYPOXIA INDUCIBLE FACTOR 1; LIPOPOLYSACCHARIDE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APBA3 GENE; ARTICLE; BONE MARROW CELL; CELL LINEAGE; CELL MOTILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENERGY YIELD; ENZYME ACTIVITY; GENE DELETION; GENE FUNCTION; GENE REPRESSION; GENETIC MANIPULATION; GLYCOLYSIS; MACROPHAGE; MINT3 GENE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SEPTIC SHOCK;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELLS, CULTURED; DRUG RESISTANCE; ENERGY METABOLISM; GENE DELETION; HYPOXIA-INDUCIBLE FACTOR 1; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, KNOCKOUT; SHOCK, SEPTIC;

MUS;

EID: 80052778834     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.271726     Document Type: Article

References (33)

1. Coussens, L. M., and Werb, Z. (2002) Nature 420, 860-867
2. Pollard, J. W. (2009) Nat. Rev. Immunol. 9, 259-270
3. Condeelis, J., and Pollard, J. W. (2006) Cell 124, 263-266
4. Aragonés, J., Fraisl, P., Baes, M., and Carmeliet, P. (2009) Cell Metab. 9, 11-22
5. Cramer, T., Yamanishi, Y., Clausen, B. E., Förster, I., Pawlinski, R., Mackman, N., Haase, V. H., Jaenisch, R., Corr, M., Nizet, V., Firestein, G. S., Gerber, H. P., Ferrara, N., and Johnson, R. S. (2003) Cell 112, 645-657
6. Michl, J., Ohlbaum, D. J., and Silverstein, S. C. (1976) J. Exp. Med. 144, 1465-1483
7. Denko, N. C. (2008) Nat. Rev. Cancer 8, 705-713
8. Kaelin, W. G., Jr., and Ratcliffe, P. J. (2008) Mol. Cell 30, 393-402
9. Semenza, G. L. (2009) Curr. Opin. Genet. Dev. 20, 51-56
10. Lando, D., Peet, D. J., Gorman, J. J., Whelan, D. A., Whitelaw, M. L., and Bruick, R. K. (2002) Genes Dev. 16, 1466-1471
11. Mahon, P. C., Hirota, K., and Semenza, G. L. (2001) Genes Dev. 15, 2675-2686
12. Sakamoto, T., Niiya, D., and Seiki, M. (2011) J. Biol. Chem. 286, 14691-14704
13. Sakamoto, T., and Seiki, M. (2009) J. Biol. Chem. 284, 30350-30359
14. Sakamoto, T., and Seiki, M. (2010) J. Biol. Chem. 285, 29951-29964
15. Itoh, Y., and Seiki, M. (2006) J. Cell Physiol. 206, 1-8
16. Kessenbrock, K., Plaks, V., and Werb, Z. (2010) Cell 141, 52-67
17. Sakamoto, T., and Seiki, M. (2009) Genes Cells 14, 617-626
18. Okamoto, M., and Südhof, T. C. (1998) Eur. J. Cell Biol. 77, 161-165
19. Tanahashi, H., and Tabira, T. (1999) Biochem. Biophys. Res. Commun. 255, 663-667
20. Han, J., Wang, Y., Wang, S., and Chi, C. (2008) J. Cell Sci. 121, 2217-2223
21. Schneider, F., Sukhova, G. K., Aikawa, M., Canner, J., Gerdes, N., Tang, S. M., Shi, G. P., Apte, S. S., and Libby, P. (2008) Circulation 117, 931-939
22. Ho, A., Morishita, W., Atasoy, D., Liu, X., Tabuchi, K., Hammer, R. E., Malenka, R. C., and Südhof, T. C. (2006) J. Neurosci 26, 13089-13101
23. Kanki, H., Suzuki, H., and Itohara, S. (2006) Exp. Anim. 55, 137-141
24. Taniwaki, K., Fukamachi, H., Komori, K., Ohtake, Y., Nonaka, T., Sakamoto, T., Shiomi, T., Okada, Y., Itoh, T., Itohara, S., Seiki, M., and Yana, I. (2007) Cancer Res. 67, 4311-4319
25. Riedemann, N. C., Guo, R. F., and Ward, P. A. (2003) Nat. Med. 9, 517-524
26. Ozmen, L., Pericin, M., Hakimi, J., Chizzonite, R. A., Wysocka, M., Trinchieri, G., Gately, M., and Garotta, G. (1994) J. Exp. Med. 180, 907-915
27. Miller, C. C., McLoughlin, D. M., Lau, K. F., Tennant, M. E., and Rogelj, B. (2006) Trends Neurosci 29, 280-285
28. Holmquist-Mengelbier, L., Fredlund, E., Löfstedt, T., Noguera, R., Navarro, S., Nilsson, H., Pietras, A., Vallon-Christersson, J., Borg, A., Gradin, K., Poellinger, L., and Påhlman, S. (2006) Cancer Cell 10, 413-423
29. Majmundar, A. J., Wong, W. J., and Simon, M. C. (2010) Mol. Cell 40, 294-309
30. Koivunen, P., Hirsilä, M., Günzler, V., Kivirikko, K. I., and Myllyharju, J. (2004) J. Biol. Chem. 279, 9899-9904
31. Imtiyaz, H. Z., Williams, E. P., Hickey, M. M., Patel, S. A., Durham, A. C., Yuan, L. J., Hammond, R., Gimotty, P. A., Keith, B., and Simon, M. C. (2010) J. Clin. Invest. 120, 2699-2714
32. Ota, I., Li, X. Y., Hu, Y., and Weiss, S. J. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 20318-20323
33. Pulyaeva, H., Bueno, J., Polette, M., Birembaut, P., Sato, H., Seiki, M., and Thompson, E. W. (1997) Clin. Exp. Metastasis 15, 111-120