The small molecule PKA-specific cyclic AMP analogue as an inducer of osteoblast-like cells differentiation and mineralization

Journal of Tissue Engineering and Regenerative Medicine

Volumn 6, Issue 1, 2012, Pages 40-48

  Lo, Kevin W H ^a   Kan, Ho Man ^a   Ashe, Keshia M ^b   Laurencin, Cato T ^a,b  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Bone tissue engineering; CAMP; Differentiation; Growth factors; Osteoblast; Osteogenesis; PKA signalling cascade; Small molecules

Indexed keywords

BIOMINERALIZATION; CELL PROLIFERATION; CELL SIGNALING; MINERALOGY; MOLECULES; PHOSPHATASES; TISSUE REGENERATION;

BONE TISSUE ENGINEERING; CAMP; CYCLIC ADENOSINE; DIFFERENTIATION; GROWTH FACTOR; OSTEOGENESIS; PROTEIN KINASE A; PROTEIN KINASE A SIGNALING CASCADE; SIGNALING CASCADES; SMALL MOLECULES;

BONE;

ALKALINE PHOSPHATASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N 6 BENZOYLADENOSINE 3',5' CYCLIC MONOPHOSPHATE; OSTEOCALCIN; OSTEOPONTIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ARTICLE; BIOMINERALIZATION; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 80052708936     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.395     Document Type: Article

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