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Volumn 14, Issue 9, 1999, Pages 1504-1512

Anabolic or catabolic responses of MC3T3-E1 osteoblastic cells to parathyroid hormone depend on time and duration of treatment

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; MESSENGER RNA; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN; RECEPTOR PROTEIN;

EID: 0032835840     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1999.14.9.1504     Document Type: Article
Times cited : (101)

References (55)
  • 1
    • 0000683821 scopus 로고
    • Studies of calcium phosphorus metabolism: Study of bone trabeculae as ready available reserve supply of calcium
    • Bauer W, Aub JC, Albright F 1929 Studies of calcium phosphorus metabolism: Study of bone trabeculae as ready available reserve supply of calcium. J Exp Med 49:145-162.
    • (1929) J Exp Med , vol.49 , pp. 145-162
    • Bauer, W.1    Aub, J.C.2    Albright, F.3
  • 2
    • 84933876926 scopus 로고
    • On the stimulation of new-bone-formation with parathyroid extract, irradiated ergosterol
    • Selye H 1932 On the stimulation of new-bone-formation with parathyroid extract, irradiated ergosterol. Endocrinology 16:547-558.
    • (1932) Endocrinology , vol.16 , pp. 547-558
    • Selye, H.1
  • 4
    • 0023915687 scopus 로고
    • Human parathyroid hormone (1-34) increases bone mass in ovariectomized and orchidectomized rats
    • Hock JM, Gera I, Fonseca J, Raisz LG 1988 Human parathyroid hormone (1-34) increases bone mass in ovariectomized and orchidectomized rats. Endocrinology 122:2899-2904.
    • (1988) Endocrinology , vol.122 , pp. 2899-2904
    • Hock, J.M.1    Gera, I.2    Fonseca, J.3    Raisz, L.G.4
  • 5
    • 0025896380 scopus 로고
    • The anabolic effects of human parathyroid hormone (hPTH) on rat vertebral body mass are also reflected in the quality of bone, assessed by biomechanical testing: A comparison study between hPTH-(1-34) and hPTH-(1-84)
    • Mosekilde L, Sogaard CH, Danielsen CC, Torring O 1991 The anabolic effects of human parathyroid hormone (hPTH) on rat vertebral body mass are also reflected in the quality of bone, assessed by biomechanical testing: A comparison study between hPTH-(1-34) and hPTH-(1-84). Endocrinology 129:421-428.
    • (1991) Endocrinology , vol.129 , pp. 421-428
    • Mosekilde, L.1    Sogaard, C.H.2    Danielsen, C.C.3    Torring, O.4
  • 6
    • 0026524071 scopus 로고
    • Contrasting effects of parathyroid hormone and insulin-like growth factor I in an aged ovariectomized rat model of postmenopausal osteoporosis
    • Ibbotson KJ, Orcutt CM, D'Souza SM, Paddock CL, Arthur JA, Jankowsky ML, Boyce RW 1992 Contrasting effects of parathyroid hormone and insulin-like growth factor I in an aged ovariectomized rat model of postmenopausal osteoporosis. J Bone Miner Res 7:425-432.
    • (1992) J Bone Miner Res , vol.7 , pp. 425-432
    • Ibbotson, K.J.1    Orcutt, C.M.2    D'Souza, S.M.3    Paddock, C.L.4    Arthur, J.A.5    Jankowsky, M.L.6    Boyce, R.W.7
  • 7
    • 0026584625 scopus 로고
    • Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone
    • Hock JM, Gera I 1992 Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone. J Bone Miner Res 7:65-72.
    • (1992) J Bone Miner Res , vol.7 , pp. 65-72
    • Hock, J.M.1    Gera, I.2
  • 9
    • 0027476140 scopus 로고
    • Parathyroid hormone is more effective than estrogen or bisphosphonates for restoration of lost bone mass in ovariectomized rats
    • Wronski TJ, Yen CF, Qi H, Dann LM 1993 Parathyroid hormone is more effective than estrogen or bisphosphonates for restoration of lost bone mass in ovariectomized rats. Endocrinology 132:823-831.
    • (1993) Endocrinology , vol.132 , pp. 823-831
    • Wronski, T.J.1    Yen, C.F.2    Qi, H.3    Dann, L.M.4
  • 11
    • 0029056618 scopus 로고
    • A comparison of the anabolic effects of parathyroid hormone at skeletal sites with moderate and severe osteopenia in aged ovariectomized rats
    • Qi H, Li M, Wronski TJ 1995 A comparison of the anabolic effects of parathyroid hormone at skeletal sites with moderate and severe osteopenia in aged ovariectomized rats. J Bone Miner Res 10:948-955.
    • (1995) J Bone Miner Res , vol.10 , pp. 948-955
    • Qi, H.1    Li, M.2    Wronski, T.J.3
  • 12
    • 0029144772 scopus 로고
    • Parathyroid hormone monotherapy and cotherapy with antiresorptive agents restore vertebral bone mass and strength in aged ovariectomized rats
    • Li M, Mosekilde L, Sogaard CH, Thomsen JS, Wronski TJ 1995 Parathyroid hormone monotherapy and cotherapy with antiresorptive agents restore vertebral bone mass and strength in aged ovariectomized rats. Bone 16:629-635.
    • (1995) Bone , vol.16 , pp. 629-635
    • Li, M.1    Mosekilde, L.2    Sogaard, C.H.3    Thomsen, J.S.4    Wronski, T.J.5
  • 13
    • 0022479815 scopus 로고
    • Parathyroid hormone stimulates the proliferation of cells derived from human bone
    • MacDonald BR, Gallagher JA, Russell RG 1986 Parathyroid hormone stimulates the proliferation of cells derived from human bone. Endocrinology 118:2445-2449.
    • (1986) Endocrinology , vol.118 , pp. 2445-2449
    • MacDonald, B.R.1    Gallagher, J.A.2    Russell, R.G.3
  • 14
    • 0024532580 scopus 로고
    • Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures
    • Canalis E, Centrella M, Burch W, McCarthy TL 1989 Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures. J Clin Invest 83:60-65.
    • (1989) J Clin Invest , vol.83 , pp. 60-65
    • Canalis, E.1    Centrella, M.2    Burch, W.3    McCarthy, T.L.4
  • 15
    • 0024536688 scopus 로고
    • Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone
    • McCarthy TL, Centrella M, Canalis E 1989 Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone. Endocrinology 124:1247-1253.
    • (1989) Endocrinology , vol.124 , pp. 1247-1253
    • McCarthy, T.L.1    Centrella, M.2    Canalis, E.3
  • 16
    • 0028148489 scopus 로고
    • Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow
    • Nishida S, Yamaguchi A, Tanizawa T, Endo N, Mashiba T, Uchiyama Y, Suda T, Yoshiki S, Takahashi HE 1994 Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow. Bone 15:717-723.
    • (1994) Bone , vol.15 , pp. 717-723
    • Nishida, S.1    Yamaguchi, A.2    Tanizawa, T.3    Endo, N.4    Mashiba, T.5    Uchiyama, Y.6    Suda, T.7    Yoshiki, S.8    Takahashi, H.E.9
  • 17
    • 0028828626 scopus 로고
    • Intermittent parathyroid hormone treatment increases osteoblast number, steady state messenger ribonucleic acid levels for osteocalcin, and bone formation in tibial metaphysis of hypophysectomized female rats
    • Schmidt IU, Dobnig H, Turner RT 1995 Intermittent parathyroid hormone treatment increases osteoblast number, steady state messenger ribonucleic acid levels for osteocalcin, and bone formation in tibial metaphysis of hypophysectomized female rats. Endocrinology 136:5127-5134.
    • (1995) Endocrinology , vol.136 , pp. 5127-5134
    • Schmidt, I.U.1    Dobnig, H.2    Turner, R.T.3
  • 18
    • 0029116964 scopus 로고
    • Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells
    • Dobnig H, Turner RT 1995 Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells. Endocrinology 136:3632-3638.
    • (1995) Endocrinology , vol.136 , pp. 3632-3638
    • Dobnig, H.1    Turner, R.T.2
  • 19
    • 0025047391 scopus 로고
    • Characterization of the major parathyroid hormone target cell in the endosteal metaphysis of rat long bones
    • Rouleau MF, Mitchell J, Goltzman D 1990 Characterization of the major parathyroid hormone target cell in the endosteal metaphysis of rat long bones. J Bone Miner Res 5:1043-1053.
    • (1990) J Bone Miner Res , vol.5 , pp. 1043-1053
    • Rouleau, M.F.1    Mitchell, J.2    Goltzman, D.3
  • 21
    • 0026598246 scopus 로고
    • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium
    • Abou-Samra AB, Jüppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts JT Jr, Kronenberg HM, Segre GV 1992 Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA 89:2732-2736.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2732-2736
    • Abou-Samra, A.B.1    Jüppner, H.2    Force, T.3    Freeman, M.W.4    Kong, X.F.5    Schipani, E.6    Urena, P.7    Richards, J.8    Bonventre, J.V.9    Potts J.T., Jr.10    Kronenberg, H.M.11    Segre, G.V.12
  • 22
    • 0028054803 scopus 로고
    • Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: In situ localization of its receptor and c-fos messenger ribonucleic acids
    • Lee K, Deeds JD, Chiba S, Un-No M, Bond AT, Segre GV 1994 Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: In situ localization of its receptor and c-fos messenger ribonucleic acids. Endocrinology 134:441-450.
    • (1994) Endocrinology , vol.134 , pp. 441-450
    • Lee, K.1    Deeds, J.D.2    Chiba, S.3    Un-No, M.4    Bond, A.T.5    Segre, G.V.6
  • 23
    • 25044438210 scopus 로고    scopus 로고
    • Characterization of alternatively spliced isoforms of the PTH/PTHrP receptor messenger RNA expressed in human kidney and bone cells
    • abstract
    • Jobert AS, Fernandes I, Turner G, Prie D, Friedlander G, Silve C 1996 Characterization of alternatively spliced isoforms of the PTH/PTHrP receptor messenger RNA expressed in human kidney and bone cells. J Bone Miner Res 11 (Suppl 1):S303 (abstract).
    • (1996) J Bone Miner Res , vol.11 , Issue.SUPPL. 1
    • Jobert, A.S.1    Fernandes, I.2    Turner, G.3    Prie, D.4    Friedlander, G.5    Silve, C.6
  • 24
    • 0030951084 scopus 로고    scopus 로고
    • Tissue-specific transcription start sites and alternative splicing of the parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor gene: A new PTH/PTHrP receptor splice variant that lacks the signal peptide
    • Joun H, Lanske B, Karperien M, Qian F. Defize L, Abou-Samra A 1997 Tissue-specific transcription start sites and alternative splicing of the parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor gene: A new PTH/PTHrP receptor splice variant that lacks the signal peptide. Endocrinology 138:1742-1749.
    • (1997) Endocrinology , vol.138 , pp. 1742-1749
    • Joun, H.1    Lanske, B.2    Karperien, M.3    Qian, F.4    Defize, L.5    Abou-Samra, A.6
  • 25
    • 0029759907 scopus 로고    scopus 로고
    • Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages
    • Isogai Y, Akatsu T, Ishizuya T, Yamaguchi A, Hori M, Takahashi N, Suda T 1996 Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages. J Bone Miner Res 11:1384-1393.
    • (1996) J Bone Miner Res , vol.11 , pp. 1384-1393
    • Isogai, Y.1    Akatsu, T.2    Ishizuya, T.3    Yamaguchi, A.4    Hori, M.5    Takahashi, N.6    Suda, T.7
  • 26
    • 0030831889 scopus 로고    scopus 로고
    • Parathyroid hormone enhances early and suppresses late stages of osteogenic and chondrogenic development in a BMP-dependent mesenchymal differentiation system (C3H10T1/2)
    • Hollnagel A, Ahrens M, Gross G 1997 Parathyroid hormone enhances early and suppresses late stages of osteogenic and chondrogenic development in a BMP-dependent mesenchymal differentiation system (C3H10T1/2). J Bone Miner Res 12:1993-2004.
    • (1997) J Bone Miner Res , vol.12 , pp. 1993-2004
    • Hollnagel, A.1    Ahrens, M.2    Gross, G.3
  • 27
    • 0029900046 scopus 로고    scopus 로고
    • PTH/PTHrP receptor is temporally regulated during osteoblast differentiation and is associated with collagen synthesis
    • McCauley LK, Koh AJ, Beecher CA, Cui Y, Rosol TJ, Franceschi RT 1996 PTH/PTHrP receptor is temporally regulated during osteoblast differentiation and is associated with collagen synthesis. J Cell Biochem 61:638-647.
    • (1996) J Cell Biochem , vol.61 , pp. 638-647
    • McCauley, L.K.1    Koh, A.J.2    Beecher, C.A.3    Cui, Y.4    Rosol, T.J.5    Franceschi, R.T.6
  • 28
    • 0030817807 scopus 로고    scopus 로고
    • Temporal changes of mRNA expression of matrix proteins and parathyroid hormone and parathyroid hormone-related protein (PTH/ PTHrP) receptor in bone development
    • Kondo H, Ohyama T, Ohya K, Kasugai S 1997 Temporal changes of mRNA expression of matrix proteins and parathyroid hormone and parathyroid hormone-related protein (PTH/ PTHrP) receptor in bone development. J Bone Miner Res 12:2089-2097.
    • (1997) J Bone Miner Res , vol.12 , pp. 2089-2097
    • Kondo, H.1    Ohyama, T.2    Ohya, K.3    Kasugai, S.4
  • 29
    • 0030045371 scopus 로고    scopus 로고
    • Expression of the parathyroid hormone receptor and correlation with other osteoblastic parameters in fetal rat osteoblasts
    • Bos MP, van der Meer JM, Feyen JH, Herrmann-Erlee MP 1996 Expression of the parathyroid hormone receptor and correlation with other osteoblastic parameters in fetal rat osteoblasts. Calcif Tissue Int 58:95-100.
    • (1996) Calcif Tissue Int , vol.58 , pp. 95-100
    • Bos, M.P.1    Van Der Meer, J.M.2    Feyen, J.H.3    Herrmann-Erlee, M.P.4
  • 30
    • 0030962888 scopus 로고    scopus 로고
    • Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells
    • Ishizuya T, Yokose S, Hori M, Noda T, Suda T, Yoshiki S, Yamaguchi A 1997 Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells. J Clin Invest 99:2961-2970.
    • (1997) J Clin Invest , vol.99 , pp. 2961-2970
    • Ishizuya, T.1    Yokose, S.2    Hori, M.3    Noda, T.4    Suda, T.5    Yoshiki, S.6    Yamaguchi, A.7
  • 31
    • 0001201488 scopus 로고
    • Establishment of a clonal osteogenic cell line from newborn mouse calvaria
    • Kodama H, Amagai Y, Sudo H, Yamamoto S 1981 Establishment of a clonal osteogenic cell line from newborn mouse calvaria. Jpn J Oral Biol 23:899-901.
    • (1981) Jpn J Oral Biol , vol.23 , pp. 899-901
    • Kodama, H.1    Amagai, Y.2    Sudo, H.3    Yamamoto, S.4
  • 32
    • 0026690364 scopus 로고
    • Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: An in vitro model of osteoblast development
    • Quarles LD, Yohay DA, Lever LW, Caton R, Wenstrup RJ 1992 Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: An in vitro model of osteoblast development. J Bone Miner Res 7:683-692.
    • (1992) J Bone Miner Res , vol.7 , pp. 683-692
    • Quarles, L.D.1    Yohay, D.A.2    Lever, L.W.3    Caton, R.4    Wenstrup, R.J.5
  • 33
    • 0026746159 scopus 로고
    • Hormonal regulation of intercellular communication: Parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells
    • Schiller PC, Mehta PP, Roos BA, Howard GA 1992 Hormonal regulation of intercellular communication: Parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells. Mol Endocrinol 6:1433-1440.
    • (1992) Mol Endocrinol , vol.6 , pp. 1433-1440
    • Schiller, P.C.1    Mehta, P.P.2    Roos, B.A.3    Howard, G.A.4
  • 35
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomezynsky P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomezynsky, P.1    Sacchi, N.2
  • 36
    • 0018850985 scopus 로고
    • A simple, rapid, and sensitive DNA assay procedure
    • Labarca C, Paigen K 1980 A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 102:344-352.
    • (1980) Anal Biochem , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 37
    • 0019830747 scopus 로고
    • 3 stimulates the alkaline phosphatase activity of osteoblast-like cells
    • 3 stimulates the alkaline phosphatase activity of osteoblast-like cells. J Biol Chem 256:7115-7117.
    • (1981) J Biol Chem , vol.256 , pp. 7115-7117
    • Manolagas, S.C.1    Burton, D.W.2    Deftos, L.J.3
  • 38
  • 39
    • 0018641554 scopus 로고
    • Identification of hydroxyapatite crystals in synovial fluid
    • Halverson PB, McCarty DJ 1979 Identification of hydroxyapatite crystals in synovial fluid. Arthritis Rheum 22:389-395.
    • (1979) Arthritis Rheum , vol.22 , pp. 389-395
    • Halverson, P.B.1    McCarty, D.J.2
  • 40
    • 0028341473 scopus 로고
    • Signal transduction pathways mediating parathyroid hormone regulation of osteoblastic gene expression
    • Partridge NC, Bloch SR, Pearman AT 1994 Signal transduction pathways mediating parathyroid hormone regulation of osteoblastic gene expression. J Cell Biochem 55:321-327.
    • (1994) J Cell Biochem , vol.55 , pp. 321-327
    • Partridge, N.C.1    Bloch, S.R.2    Pearman, A.T.3
  • 41
    • 0030946570 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of osteoblast-like MC3T3-E1 cells: Changes of bradykinin-induced prostaglandin E2 production during osteoblast maturation
    • Leis HJ, Hulla W, Gruber R, Huber E, Zach D. Gleispach H, Windischhofer W 1997 Phenotypic heterogeneity of osteoblast-like MC3T3-E1 cells: Changes of bradykinin-induced prostaglandin E2 production during osteoblast maturation. J Bone Miner Res 12:541-551.
    • (1997) J Bone Miner Res , vol.12 , pp. 541-551
    • Leis, H.J.1    Hulla, W.2    Gruber, R.3    Huber, E.4    Zach, D.5    Gleispach, H.6    Windischhofer, W.7
  • 45
    • 0028321790 scopus 로고
    • Isolation and characterization of gap junctions in the osteoblastic MC3T3-E1 cell line
    • Yamaguchi DT, Ma D, Lee A, Huang J, Gruber HE 1994 Isolation and characterization of gap junctions in the osteoblastic MC3T3-E1 cell line. J Bone Miner Res 9:791-803.
    • (1994) J Bone Miner Res , vol.9 , pp. 791-803
    • Yamaguchi, D.T.1    Ma, D.2    Lee, A.3    Huang, J.4    Gruber, H.E.5
  • 48
    • 0027968667 scopus 로고
    • Gap junction proteins exhibit early and specific expression during intramembranous bone formation in the developing chick mandible
    • Minkoff R, Rundus VR, Parker SB, Hertzberg EL, Laing JG, Beyer EC 1994 Gap junction proteins exhibit early and specific expression during intramembranous bone formation in the developing chick mandible. Anat Embryol 190:231-241.
    • (1994) Anat Embryol , vol.190 , pp. 231-241
    • Minkoff, R.1    Rundus, V.R.2    Parker, S.B.3    Hertzberg, E.L.4    Laing, J.G.5    Beyer, E.C.6
  • 49
    • 0030833934 scopus 로고    scopus 로고
    • PTH up-regulation of connexin 43 gene expression in osteoblasts depends on cell phenotype
    • Schiller PC, Roos BA, Howard GA 1997 PTH up-regulation of connexin 43 gene expression in osteoblasts depends on cell phenotype. J Bone Miner Res 12:2005-2013.
    • (1997) J Bone Miner Res , vol.12 , pp. 2005-2013
    • Schiller, P.C.1    Roos, B.A.2    Howard, G.A.3
  • 50
    • 15844394777 scopus 로고    scopus 로고
    • Gap junctional communication contributes to hormonal responsiveness in osteoblastic networks
    • Vander Molen MA, Rubin CT, McLeod KJ, McCauley LK, Donahue HJ 1996 Gap junctional communication contributes to hormonal responsiveness in osteoblastic networks. J Biol Chem 271:12165-12171.
    • (1996) J Biol Chem , vol.271 , pp. 12165-12171
    • Vander Molen, M.A.1    Rubin, C.T.2    McLeod, K.J.3    McCauley, L.K.4    Donahue, H.J.5
  • 51
    • 0022005644 scopus 로고
    • Glucocorticoid regulation of alkaline phosphatase in the osteoblastic osteosarcoma cell line ROS 17/2.8
    • Majeska RJ, Nair BC, Rodan GA 1985 Glucocorticoid regulation of alkaline phosphatase in the osteoblastic osteosarcoma cell line ROS 17/2.8. Endocrinology 116:170-179.
    • (1985) Endocrinology , vol.116 , pp. 170-179
    • Majeska, R.J.1    Nair, B.C.2    Rodan, G.A.3
  • 52
    • 0005413478 scopus 로고    scopus 로고
    • Selective stimulation of apoptosis in trabecular osteoblasts and osteocytes of young rats treated with once daily hPTH 1-34 to increase bone mass
    • abstract
    • Yang X, Liang JD, Wolfe J, Cain RL, Onyia JE, Santerre RF, Hock JM 1997 Selective stimulation of apoptosis in trabecular osteoblasts and osteocytes of young rats treated with once daily hPTH 1-34 to increase bone mass. J Bone Miner Res 12 (Suppl 1):S316 (abstract).
    • (1997) J Bone Miner Res , vol.12 , Issue.SUPPL. 1
    • Yang, X.1    Liang, J.D.2    Wolfe, J.3    Cain, R.L.4    Onyia, J.E.5    Santerre, R.F.6    Hock, J.M.7
  • 54
    • 0030024143 scopus 로고    scopus 로고
    • Effects of parathyroid hormone and agonists of the adenylyl cyclase and protein kinase C pathways on bone cell proliferation
    • Sabatini M, Lesur C, Pacherie M, Pastoureau P, Kucharczyk N, Fauchere JL, Bonnet J 1996 Effects of parathyroid hormone and agonists of the adenylyl cyclase and protein kinase C pathways on bone cell proliferation. Bone 18:59-65.
    • (1996) Bone , vol.18 , pp. 59-65
    • Sabatini, M.1    Lesur, C.2    Pacherie, M.3    Pastoureau, P.4    Kucharczyk, N.5    Fauchere, J.L.6    Bonnet, J.7
  • 55
    • 0029855956 scopus 로고    scopus 로고
    • Truncation of the amino terminus of PTH alters its anabolic activity on bone in vivo
    • Hilliker S, Wergedal JE, Gruber HE, Bettica P, Baylink DJ 1996 Truncation of the amino terminus of PTH alters its anabolic activity on bone in vivo. Bone 19:469-477.
    • (1996) Bone , vol.19 , pp. 469-477
    • Hilliker, S.1    Wergedal, J.E.2    Gruber, H.E.3    Bettica, P.4    Baylink, D.J.5


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