A biodegradable polymer as a cytokine delivery system for inducing bone formation

Nature Biotechnology

Volumn 19, Issue 4, 2001, Pages 332-335

  Saito, Naoto ^a   Okada, Takao ^b   Horiuchi, Hiroshi ^a   Murakami, Narumichi ^a   Takahashi, Jun ^a   Nawata, Masashi ^a   Ota, Hiroshi ^a   Nozaki, Kazutoshi ^c   Takaoka, Kunio ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Taki Chemical Co Ltd   (Japan)

^c ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADATION; COPOLYMERS; ETHYLENE; GLYCOLS; IMPLANTS (SURGICAL); POLYMERS; PROTEINS;

BONE MORPHOGENETIC PROTEINS (BMP); CYTOKINE DELIVERY SYSTEM;

BONE;

BONE MORPHOGENETIC PROTEIN; CALCIUM; COPOLYMER; MACROGOL; POLYLACTIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; BONE; BONE DEFECT; BONE REMODELING; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; MALE; MOUSE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE AND BONES; BONE DEVELOPMENT; BONE MORPHOGENETIC PROTEINS; CALCIUM; COLLAGEN; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; HUMANS; ILIUM; LACTATES; MALE; MICE; POLYETHYLENE GLYCOLS; POLYMERS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; X-RAYS;

ANIMALIA;

EID: 0035066563     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/86715     Document Type: Article

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