RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5971-5974

  Krysko, Andrei A ^a   Samoylenko, Georgiy V ^a   Polishchuk, Pavel G ^a,b   Andronati, Sergei A ^a   Kabanova, Tatyana A ^a   Khristova, Tetiana M ^a,b   Kuz'Min, Victor E ^a   Kabanov, Vladimir M ^a   Krysko, Olga L ^a   Varnek, Alexandre A ^b   Grygorash, Ruslan Ya ^a  

^a A V BOGATSKY PHYSICO CHEMICAL INSTITUTE   (Ukraine)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

IIb 3; Fibrinogen receptor antagonists; Phthalimidine; Platelet aggregation; RGD mimetics

Indexed keywords

ALPHAIIB BETA3 INTEGRIN; ARGININE; ARGINYLGLYCYLASPARTIC ACID; BENZOIC ACID DERIVATIVE; BUTYRIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; FIBRINOGEN RECEPTOR; FLUORESCEIN ISOTHIOCYANATE; INTEGRIN; LIGAND; PHTHALIMIDE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION INHIBITION;

ARGININE; BLOOD PLATELETS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FIBRINOGEN; FLUORESCEIN-5-ISOTHIOCYANATE; HUMANS; ISOQUINOLINES; LIGANDS; OLIGOPEPTIDES; PHTHALIMIDES; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; RECEPTORS, FIBRINOGEN; SOFTWARE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

EID: 80052560135     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.07.063     Document Type: Article

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