The development of a manufacturing route for the GPIIb/IIIa receptor antagonist SB-214857-A. Part 2: Conversion of the key intermediate SB-235349 to SB-214857-A

Organic Process Research and Development

Volumn 7, Issue 5, 2003, Pages 663-675

  Atkins, Richard J ^a   Banks, Adam ^a   Bellingham, Richard K ^a   Breen, Gary F ^a   Carey, John S ^a   Etridge, Stephen K ^a   Hayes, Jerome F ^a   Hussain, Nigel ^a   Morgan, David O ^a   Oxley, Paul ^a   Passey, Stephen C ^a   Walsgrove, Timothy C ^a   Wells, Andrew S ^a,b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,5 TETRAHYDRO 4 METHYL 3 OXO 1H 1,4 BENZODIAZEPIN 2 ACETIC ACID METHYL ESTER; ACETIC ACID DERIVATIVE; AMPHOLYTE; BENZODIAZEPINE DERIVATIVE; CHARCOAL; CHLORIDE; FIBRINOGEN RECEPTOR ANTAGONIST; LOTRAFIBAN; PALLADIUM; PIPERIDINE DERIVATIVE; PYRIDINE DERIVATIVE; SB 235349; SODIUM DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HYDROGENATION; IODINATION;

EID: 0141924726     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op034023k     Document Type: Article

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