DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress

Biology of Reproduction

Volumn 85, Issue 3, 2011, Pages 524-535

  Mu, X F ^a   Jin, X L ^a   Farnham, M M J ^a   Li, Y ^a   O'Neill, C ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Apoptosis; Ataxia telangiectasia and Rad3 related; Ataxia telangiectasia mutated; Cell cycle; Checkpoint; DNA damage; Early development; Embryo; H2AFX; Transformation related protein 53; Tumor suppressor gene

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ATM PROTEIN; ATR PROTEIN; CAFFEINE; CISPLATIN; HISTONE H2A; HISTONE H2AX; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; DNA STRAND BREAKAGE; EMBRYO; EMBRYO DEVELOPMENT; ENZYME INHIBITION; FEMALE; GENETIC VARIABILITY; GENOTOXICITY; HISTONE PHOSPHORYLATION; MALE; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET IRRADIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL CYCLE PROTEINS; CISPLATIN; DNA DAMAGE; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; MICE; MICE, INBRED C57BL; PREGNANCY; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; ULTRAVIOLET RAYS;

ATAXIA TELANGIECTASIA;

EID: 80052521510     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.110.089334     Document Type: Article

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