Overexpression of chitinase 3-Like 1/YKL-40 in Lung-Specific IL-18-transgenic mice, smokers and COPD

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Sakazaki, Yuki ^a   Hoshino, Tomoaki ^a   Takei, Satoko ^a   Sawada, Masanori ^a   Oda, Hanako ^a   Takenaka, Shin ichi ^a   Imaoka, Haruki ^a   Matsunaga, Kazuko ^a   Ota, Toshio ^b   Abe, Yuzuru ^b   Miki, Ichiro ^b   Fujimoto, Kiminori ^a   Kawayama, Tomotaka ^a   Kato, Seiya ^c   Aizawa, Hisamichi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

^c UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHITINASE; CHITINASE 3 LIKE 1 PROTEIN; INTERLEUKIN 13; INTERLEUKIN 18; MESSENGER RNA; UNCLASSIFIED DRUG; YKL 40 PROTEIN; ADIPOCYTOKINE; CHI3L1 PROTEIN, HUMAN; CHIA PROTEIN, HUMAN; LECTIN; SCLEROPROTEIN;

ACIDIC MAMMALIAN CHITINASE GENE; ADULT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHITINASE 3 LIKE 1 GENE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; EMPHYSEMA; FEMALE; GENE; GENE CLUSTER; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE OVEREXPRESSION; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; INTERLEUKIN 13 GENE; LUNG FUNCTION TEST; MALE; MARKER GENE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOKING HABIT; TRANSGENIC MOUSE; WILD ANIMAL; YKL 40 GENE; ANIMAL; C57BL MOUSE; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; METABOLISM; MIDDLE AGED; SMOKING;

MAMMALIA; MURINAE; MUS; MUS MUSCULUS;

ADIPOKINES; ANIMALS; CHITINASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HUMANS; INTERLEUKIN-13; INTERLEUKIN-18; LECTINS; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMOKING;

EID: 80052520882     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024177     Document Type: Article

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