Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema

American Journal of Respiratory Cell and Molecular Biology

Volumn 44, Issue 6, 2011, Pages 777-786

  Matsuura, Hiroshi ^a   Hartl, Dominik ^a   Kang, Min Jong ^a   Dela Cruz, Charles S ^a   Koller, Barbara ^a   Chupp, Geoffrey L ^a   Homer, Robert J ^a   Zhou, Yang ^a   Cho, Won Kyung ^a   Elias, Jack A ^a   Lee, Chun Geun ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cigarette smoke; COPD; Emphysema; YKL 40 BRP 39

Indexed keywords

BINDING PROTEIN; BREAST REGRESSION PROTEIN 39; CIGARETTE SMOKE; INTERLEUKIN 18; UNCLASSIFIED DRUG;

ADULT; AGED; AMBIENT AIR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; LUNG ALVEOLUS CELL; LUNG EMPHYSEMA; LUNG LAVAGE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SMOKING; SOFT TISSUE INFLAMMATION;

AGED; ANIMALS; EMPHYSEMA; FEMALE; GLYCOPROTEINS; HUMANS; INFLAMMATION; INTERLEUKIN-18; LECTINS; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIGNAL TRANSDUCTION; SMOKE; SMOKING;

MUS;

EID: 80051559834     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0081OC     Document Type: Article

References (54)

1. Bussink AP, Speijer D, Aerts JM, Boot RG. Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases. Genetics 2007;177:959-970. (Pubitemid 350005647)
2. Homer RJ, Zhu Z, Cohn L, Lee CG, White WI, Chen S, Elias JA. Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation. Am J Physiol Lung Cell Mol Physiol 2006;291:L502-L511. (Pubitemid 44343728)
3. Mizoguchi E. Chitinase 3 - like - 1 exacerbates intestinal inflammation by enhancing bacterial adhesion and invasion in colonic epithelial cells. Gastroenterology 2006;130:398-411. (Pubitemid 43202039)
4. Lee CG, Elias JA. Role of breast regression protein - 39/YKL-40 in asthma and allergic responses. Allergy Asthma Immunol Res 2010;2:20-27.
5. Lee CG, Da Silva CA, Lee JY, Hartl D, Elias JA. Chitin regulation of immune responses: an old molecule with new roles. Curr Opin Immunol 2008;20:684-689.
6. Lee CG. Chitin, chitinases and chitinase-like proteins in allergic inflammation and tissue remodeling. Yonsei Med J 2009;50:22-30.
7. Kawada M, Hachiya Y, Arihiro A, Mizoguchi E. Role of mammalian chitinases in inflammatory conditions. Keio J Med 2007;56:21-27. (Pubitemid 46588469)
8. Letuve S, Kozhich A, Arouche N, Grandsaigne M, Reed J, Dombret MC, Kiener PA, Aubier M, Coyle AJ, Pretolani M. YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages. J Immunol 2008;181:5167-5173.
9. Wang Y, Ripa RS, Johansen JS, Gabrielsen A, Steinbruchel DA, Friis T, Bindslev L, Haack-Sorensen M, Jorgensen E, Kastrup J. YKL-40: a new biomarker in patients with acute coronary syndrome or stable coronary artery disease. Scand Cardiovasc J 2008;42:295-302.
10. Johansen JS, Jensen BV, Roslind A, Nielsen D, Price PA. Serum YKL-40: a new prognostic biomarker in cancer patients? Cancer Epidemiol Biomarkers Prev 2006;15:194-202. (Pubitemid 43342164)
11. Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, et al. A chitinase-like protein in the lung and circulation of patients with severe asthma. N Engl J Med 2007;357:2016-2027. (Pubitemid 350106709)
12. Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, et al. Effect of variation in Chi3l1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med 2008;358:1682-1691. (Pubitemid 351549915)
13. Recklies AD, White C, Ling H. The chitinase 3 - like protein human cartilage glycoprotein 39 (HC-GP39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B - mediated signalling pathways. Biochem J 2002;365:119-126. (Pubitemid 34756146)
14. Ling H, Recklies AD. The chitinase 3 - like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor - alpha. Biochem J 2004;380:651-659. (Pubitemid 38850506)
15. Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 2008;4:435-459.
16. Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645-2653. (Pubitemid 38787999)
17. MacNee W. Pathogenesis of chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005;2:258-266. (Pubitemid 41566933)
18. Churg A, Cosio M, Wright JL. Mechanisms of cigarette smoke - induced COPD: insights from animal models. Am J Physiol Lung Cell Mol Physiol 2008;294:L612-L631. (Pubitemid 351520094)
19. Yokohori N, Aoshiba K, Nagai A. Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema. Chest 2004;125:626-632. (Pubitemid 38223645)
20. Aoshiba K, Yokohori N, Nagai A. Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am J Respir Cell Mol Biol 2003;28:555-562. (Pubitemid 36543402)
21. Tuder RM, Zhen L, Cho CY, Taraseviciene-Stewart L, Kasahara Y, Salvemini D, Voelkel NF, Flores SC. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am J Respir Cell Mol Biol 2003;29:88-97. (Pubitemid 36783320)
22. Demedts IK, Demoor T, Bracke KR, Joos GF, Brusselle GG. Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res 2006;7:53.
23. Lee CG, Hartl D, Lee GR, Koller B, Matsuura H, Da Silva CA, Sohn MH, Cohn L, Homer RJ, Kozhich AA, et al. Role of breast regression protein 39 (BRP-39)/chitinase 3 - like - 1 in Th2 and IL-13 - induced tissue responses and apoptosis. J Exp Med 2009;206:1149-1166.
24. Shapiro SD. Animal models for chronic obstructive pulmonary disease: age of Klotho and Marlboro mice. Am J Respir Cell Mol Biol 2000;22:4-7. (Pubitemid 30342952)
25. Wang J, Homer RJ, Hong L, Cohn L, Lee CG, Jung S, Elias JA. Il-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production. J Immunol 2000;165:2222-2231. (Pubitemid 30643172)
26. Halbower AC, Mason RJ, Abman SH, Tuder RM. Agarose infiltration improves morphology of cryostat sections of lung. Lab Invest 1994;71:149-153. (Pubitemid 24246032)
27. Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, et al. Il-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke - induced pulmonary emphysema and inflammation. J Immunol 2007;178:1948-1959. (Pubitemid 46154668)
28. Zheng T, Zhu Z, Wang Z, Homer RJ, Ma B, Riese RJ Jr, Chapman HA Jr, Shapiro SD, Elias JA. Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J Clin Invest 2000;106:1081-1093.
29. Lee CG, Cho SJ, Kang MJ, Chapoval SP, Lee PJ, Noble PW, Yehualaeshet T, Lu B, Flavell RA, Milbrandt J, et al. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med 2004;200:377-389. (Pubitemid 39031256)
30. Rice WR, Conkright JJ, Na CL, Ikegami M, Shannon JM, Weaver TE. Maintenance of the mouse Type II cell phenotype in vitro. Am J Physiol Lung Cell Mol Physiol 2002;283:L256-L264. (Pubitemid 34803981)
31. Hartl D, He CH, Koller B, Da Silva CA, Homer R, Lee CG, Elias JA. Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells. J Biol Chem 2008;283:33472-33482.
32. Rabe KF, Hurd S, Anzueto A, Barnes PJ, Buist SA, Calverley P, Fukuchi Y, Jenkins C, Rodriguez-Roisin R, van Weel C, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007;176:532-555. (Pubitemid 47403272)
33. Kang MJ, Lee CG, Lee JY, Dela Cruz CS, Chen ZJ, Enelow R, Elias JA. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. J Clin Invest 2008;118:2771-2784.
34. Johansen JS, Olee T, Price PA, Hashimoto S, Ochs RL, Lotz M. Regulation of YKL-40 production by human articular chondrocytes. Arthritis Rheum 2001;44:826-837. (Pubitemid 32319775)
35. Barnes PJ. The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest 2008;118:3546-3556.
36. Churg A, Wang RD, Tai H, Wang X, Xie C, Wright JL. Tumor necrosis factor-alpha drives 70% of cigarette smoke - induced emphysema in the mouse. Am J Respir Crit Care Med 2004;170:492-498. (Pubitemid 39209129)
37. Kitasato Y, Hoshino T, Okamoto M, Kato S, Koda Y, Nagata N, Kinoshita M, Koga H, Yoon DY, Asao H, et al. Enhanced expression of interleukin-18 and its receptor in idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 2004;31:619-625. (Pubitemid 39587491)
38. Recklies AD, Ling H, White C, Bernier SM. Inflammatory cytokines induce production of Chi3l1 by articular chondrocytes. J Biol Chem 2005;280:41213- 41221. (Pubitemid 41832176)
39. Rehli M, Niller HH, Ammon C, Langmann S, Schwarzfischer L, Andreesen R, Krause SW. Transcriptional regulation of Chi3l1, a marker gene for late stages of macrophage differentiation. J Biol Chem 2003;278:44058-44067. (Pubitemid 37377146)
40. Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med 2005;11:491-498. (Pubitemid 40685971)
41. Kasahara Y, Tuder RM, Cool CD, Lynch DA, Flores SC, Voelkel NF. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med 2001;163:737-744. (Pubitemid 32230838)
42. Kasahara Y, Tuder RM, Taraseviciene-Stewart L, Le Cras TD, Abman S, Hirth PK, Waltenberger J, Voelkel NF. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 2000;106:1311-1319.
43. Tang K, Rossiter HB, Wagner PD, Breen EC. Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice. J Appl Physiol 2004;97:1559-1566, discussion 1549.
44. Ma B, Kang MJ, Lee CG, Chapoval S, Liu W, Chen Q, Coyle AJ, Lora JM, Picarella D, Homer RJ, et al. Role of CCR5 in IFN-gamma - induced and cigarette smoke - induced emphysema. J Clin Invest 2005;115:3460-3472. (Pubitemid 43121834)
45. Zheng T, Kang MJ, Crothers K, Zhu Z, Liu W, Lee CG, Rabach LA, Chapman HA, Homer RJ, Aldous D, et al. Role of cathepsin S - dependent epithelial cell apoptosis in IFN-gamma - induced alveolar remodeling and pulmonary emphysema. J Immunol 2005;174:8106-8115. (Pubitemid 40806322)
46. Malinda KM, Ponce L, Kleinman HK, Shackelton LM, Millis AJ. GP38K, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells. Exp Cell Res 1999;250:168-173. (Pubitemid 29391580)
47. Shackelton LM, Mann DM, Millis AJ. Identification of a 38-kDa heparin-binding glycoprotein (GP38K) in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling. J Biol Chem 1995;270:13076-13083.
48. Nishikawa KC, Millis AJ. GP38K (Chi3l1) is a novel adhesion and migration factor for vascular cells. Exp Cell Res 2003;287:79-87. (Pubitemid 36683203)
49. Shao R, Hamel K, Petersen L, Cao QJ, Arenas RB, Bigelow C, Bentley B, Yan W. YKL-40, a secreted glycoprotein, promotes tumor angiogenesis. Oncogene 2009;28:4456-4468.
50. Sohn MH, Kang MJ, Matsuura H, Bhandari V, Lee CG, Elias JA. The chitinase-like proteins breast regression protein - 39 and YKL-40 regulate hyperoxia-induced acute lung injury. Am J Respir Crit Care Med 2010; (In Press).
51. Rathcke CN, Raymond I, Kistorp C, Hildebrandt P, Faber J, Vestergaard H. Low grade inflammation as measured by levels of YKL-40: association with an increased overall and cardiovascular mortality rate in an elderly population. Int J Cardiol 2009;143(1):35-42.
52. Yanbaeva DG, Dentener MA, Creutzberg EC, Wouters EF. Systemic inflammation in COPD: is genetic susceptibility a key factor? COPD 2006;3:51-61. (Pubitemid 43869516)
53. McNicholas WT. Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med 2009;180:692-700.
54. Agapov E, Battaile JT, Tidwell R, Hachem R, Patterson GA, Pierce RA, Atkinson JJ, Holtzman MJ. Macrophage chitinase 1 stratifies chronic obstructive lung disease. Am J Respir Cell Mol Biol 2009;41:379-384.