Catalytic domain of phosphoinositide-specific phospholipase C (PLC): Mutational analysis of residues within the active site and hydrophobic ridge of PLCδ1

Journal of Biological Chemistry

Volumn 273, Issue 19, 1998, Pages 11650-11659

  Ellis, Moira V ^a   James, Stephen R ^b,c   Perisic, Olga ^d   Downes, C Peter ^b   Williams, Roger L ^d   Katan, Matilda ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c PFIZER INC   (United States)

^d MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; CALCIUM BINDING; CATALYSIS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; MICELLE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

ANIMALIA; EUKARYOTA;

EID: 0032496273     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.19.11650     Document Type: Article

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