Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation

Immunology

Volumn 95, Issue 4, 1998, Pages 625-630

  Ajuebor, M N ^a   Virag L ^b,c   Flower, R J ^a   Perretti, M ^a   Szabo C ^b,d  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d INOTEK CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ARTICLE; ENZYME INDUCTION; IMMUNOREGULATION; INFLAMMATION; LEUKOCYTE MIGRATION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CHEMOKINE CCL2; CHEMOKINES; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; GROWTH INHIBITORS; GROWTH SUBSTANCES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-10; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; MONOKINES; NEUTROPHILS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PERITONITIS; TIME FACTORS; ZYMOSAN;

EID: 0031742316     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1998.00644.x     Document Type: Article

References (47)

1. NATHAN C. (1992) Nitric oxide as a secretory product of mammalian cells. FASEB J 6, 3051.
2. SOUTHAN G.J. & SZABÓ C. (1996) Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. Biochem Pharmacol 51, 383.
3. EVANS C.H. (1995) Nitric oxide: what role does it play in inflammation and tissue destruction? Agents Actions 47, S107.
4. KILBOURN R.G., SZABÓ C. & TRABER D. (1997) Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: lessons learned from experimental and clinical studies. Shock 7, 235.
5. STICHTENOTH D.O. & FROLICH J.C. (1998) Nitric oxide and inflammatory joint diseases. Br J Rheumatol 37, 246.
6. NATHAN C. (1997) Inducible nitric oxide synthase: what difference does it make? J Clin Invest 100, 2417.
7. BRENNER T., BROCKE S., SZAFER F. et al. (1997) Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis. J Immunol 158, 2940.
8. ZINETTI M., FANTUZZI G., DELGADO R., DI SANTO E., GHEZZI P. & FRATELLI M. (1995) Endogenous nitric oxide production by human monocytic cells regulates LPS-induccd TNF production. Eur Cytokine Netw 6, 45.
9. REMICK D.G. & VILLARETE L. (1996) Regulation of cytokine gene expression by reactive oxygen and reactive nitrogen intermediates. J Leukoc Biol 59, 471.
10. MUHL H. & DINARELLO C.A. (1997) Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine. J Immunol 159, 5063.
11. HOGABOAM C.M., STEINHAUSER M.L., SCHOCK H. et al. (1998) Therapeutic effects of nitric oxide inhibition during experimental fecal peritonitis: role of interleukin-10 and monocyte chemoattractant protein 1. Infect Immun 66, 650.
12. HIERHOLZER C., HARBRECHT B., MENEZES J.M. et al. (1998) Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J Exp Med 187, 917.
13. MACMICKING J.D., NATHAN C., HOM G. et al. (1995) Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81, 641.
14. WEI X.Q., CHARLES I.G., SMITH A. et al. (1995) Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 375, 408.
15. LAUBACH V.E., SHESELY E.G., SMITHIES O. & SHERMAN P.A. (1995) Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proc Natl Acad Sci USA, 92, 10688.
16. VAN DE LOO F.A., ARNTZ O.J., VAN ENCKEVORT F.H., VAN LENT P.L. & VAN DEN BERG W.B. (1998) Reduced cartilage proteoglycan loss during zymosan-induced gonarthritis in NOS2-deficient mice and in anti-interleukin-1-treated wild-type mice with unabated joint inflammation. Arthritis Rheum 41, 634.
17. DING M., ZHANG M., WONG J.L., ROGERS N.E., IGNARRO L.J. & VOSKUHL R.R. (1998) Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice. J Immunol 160, 2560.
18. GILKESON G.S., MUDGETT J.S., SELDIN M.F. et al. (1997) Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2. J Exp Med 186, 365.
19. CATTELL V., COOK H.T., EBRAHIM H. et al. (1998) Anti-GBM glomerulonephritis in mice lacking nitric oxide synthase type 2. Kidney Int 53, 932.
20. MCCAFFERTY D.M., MUDGETT J.S., SWAIN M.G. & KUBES P. (1997) Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation. Gastroenterology 112, 1022.
21. FENYK-MELODY J.E., GARRISON A.E., BRUNNERT S.R. et al. (1998) Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene. J Immunol 160, 2940.
22. ZINGARELLI B., VIRÁG L., SZABÓ A., CUZZOCREA S., SALZMAN A.L. & SZABÓ C. (1998) Oxidation, nitration and cytostasis induction in the absence of inducible nitric oxide synthase. Int J Mol Med 1, 787.
23. GETTING S.J., FLOWER R.J. & PERRETTI M. (1997) Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. Br J Pharmacol 120, 1075.
24. HASKÓ G., SZABÓ C., NÉMETH Z.H., SALZMAN A.L. & VIZI E.S. (1998) Suppression of IL-12 production by phosphodiesterase inhibition in murine endotoxemia is IL-10 independent. Eur J Immunol 28, 468.
25. AJUEBOR M.N., FLOWER R.J., HANNON R. et al. (1998) Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model. J Leukuc Biol 63, 108.
26. BOUGHTON-SMITH N.K. & GHELANI A. (1995) Role of induced nitric oxide synthase and increased NO levels in zymosan peritonitis in the rat. Inflamm Res 44, S149.
27. CUZZOCREA S., ZINGARELLI B., SAUTEBIN L. et al. (1997) Multiple organ failure following zymosan-induced peritonitis is mediated by nitric oxide. Shock 8, 268.
28. HICKLEY M.J. & KUBES P. (1997) Role of nitric oxide in regulation of leucocyte endothelial cell interactions. Exp Physiol 82, 339.
29. HICKEY M.J., SHARKEY K.A., SIHOTA E.G. et al. (1997) Inducible nitric oxide synthase-deficient mice have enhanced leukocyte endothelium interactions in endotoxemia. FASEB J 11, 955.
30. SZABÓ C., SOUTHAN G.J. & THIEMERMANN C. (1994) Beneficial effects and improved survival in rodent models of septic shock with S-methyl-isothiourea sulfate, a novel, potent and selective inhibitor of inducible nitric oxide synthase. Proc Natl Acad Sci USA 91, 2472.
31. SOUTHAN G.J., ZINGARELLI B., O'CONNOR M., SALZMAN A.L. & SZABÓ C. (1996) Spontaneous rearrangement of aminoalkylguanidines into mercaptoalkylguanidines a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform. Br J Pharmacol 117, 619.
32. IUVONE T., VAN OSSELAER N., D'ACQUISTO F., CARNUCCIO R. & HERMAN A.G. (1997) Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat. Br J Pharmacol 121, 1637.
33. CUZZOCREA S., ZINGARELLI B., HAKE P., SALZMAN A.L. & SZABÓ C. (1998) Carrageenan-induced local inflammation: effect of mercaptoethylguanidine, a selective inhibitor of the inducible nitric oxide synthase and a scavenger of peroxynitrite. Free Rad Biol Med 24, 450.
34. VILLA L.M., SALAS E., DARLEY-USMAR V.M., RADOMSKI M.W. & MONCADA S. (1994) Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. Proc Natl Acad Sci USA 91, 12383.
35. SZABÓ C., CUZZOCREA S., ZINGARELLI B., O'CONNOR M. & SALZMAN A.L. (1997) Endothelial dysfunction in endotoxic shock: importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite. J Clin Invest 100, 723.
36. HAELENS A., WUYTS A., PROOST P., STRUYF S., OPDENNAKER G. & VAN DAMME J. (1996) Leukocyte migration and activation by murine chemokines. Immunobiology 195, 499.
37. ROLLINS B.J. (1997) Chemokines. Blood 90, 909.
38. LUSTER A.D. (1998) Chemokines chemotactic cytokines that mediate inflammation. N Engl J Med 338, 436.
39. BRAHN E., BANQUERIGO M.L., FIRESTEIN G.S., BOYLE D.L., SALZMAN A.L. & SZABÓ C. (1998) Collagen-induced arthritis: reversal by mercaptoethylguanidine, a novel anti-inflammatory agent with a combined mechanism of action. J Rheumat. 25, 1785.
40. TSAO P.S., WANG B., BUITRAGO R., SHYY J.Y. & COOKE J.P. (1997) Nitric oxide regulates monocyte chemotactic protein-1. Circulation 96, 934.
41. ZEIHER A.M., FISSLTHALER B., SCHRAY-UTZ, B. & BUSSE R. (1995) Nitric oxide modulates the expression of monocyte chemoattractant protein I in cultured human endothelial cells. Circ Res 76, 980.
42. THOMASSEN M.J., BUHROW L.T., CONNORS M.J., KANEKO F.T., ERZURUM S.C. & KAVURU M.S. (1997) Nitric oxide inhibits inflammatory cytokine production by human alveolar macrophages. Am J Respir Cell Mol Biol 17, 279.
43. SETOGUCHI K., TAKEYA M., AKAIKE T. et al. (1996) Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats. Am J Pathol 149, 2005.
44. MOSMANN T.R. (1994) Properties and function of interleukin-10. Adv Immunol 56, 1.
45. CASSATELLA M.A., MEDA L., BONORA S., CESKA M. & CONSTANTIN G. (1993) Interleukin-10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1beta in mediating the production of IL-8 triggered by lipopolysaccharide. J Exp Med 178, 2207.
46. PERRETTI M., SZABÓ C. & THIEMERMANN C. (1995) Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse. Br J Pharmacol 116, 2251.
47. HASKÓ G., VIRÁG L., EGNACZYK G., SALZMAN A.L. & SZABÓ C. (1998) The crucial role of IL-10 in the suppression of the immunological response in mice exposed to staphylococeal enterotoxin B. Eur J Immunol 28, 1417.