Ribonucleotide discrimination and reverse transcription by the human mitochondrial DNA polymerase

Journal of Biological Chemistry

Volumn 286, Issue 36, 2011, Pages 31490-31500

  Kasiviswanathan, Rajesh ^a   Copeland, William C ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; DNA POLYMERASE; DNA SYNTHESISS; HUMAN MITOCHONDRIAL DNA POLYMERASE; HYDROXYL GROUPS; MUTANT ENZYMES; REVERSE TRANSCRIPTASES; REVERSE TRANSCRIPTION; RIBONUCLEOTIDES; RNA PRIMERS; SIDE CHAIN RESIDUES; TRIPHOSPHATE;

AMINO ACIDS; DEFECTS; ENZYMES; MITOCHONDRIA; NUCLEOTIDES; POLYMERS; RNA; TRANSCRIPTION;

DNA;

DEOXYRIBONUCLEOSIDE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE GAMMA; PRIMER DNA; PRIMER RNA; RIBONUCLEOTIDE; RNA DIRECTED DNA POLYMERASE;

ARTICLE; DNA BASE COMPOSITION; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME BINDING; MITOCHONDRION; MUTANT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; RIBONUCLEOTIDE DISCRIMINATION;

DEOXYRIBONUCLEOTIDES; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; HUMANS; MUTATION, MISSENSE; REVERSE TRANSCRIPTION; RIBONUCLEOTIDES; SUBSTRATE SPECIFICITY;

EID: 80052407884     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.252460     Document Type: Article

References (44)

1. Nick McElhinny, S. A., Kumar, D., Clark, A. B., Watt, D. L., Watts, B. E., Lundström, E. B., Johansson, E., Chabes, A., and Kunkel, T. A. (2010) Nat. Chem. Biol. 6, 774-781
2. Nick McElhinny, S. A., Watts, B. E., Kumar, D., Watt, D. L., Lundström, E. B., Burgers, P. M., Johansson, E., Chabes, A., and Kunkel, T. A. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 4949-4954
3. Cavanaugh, N. A., Beard, W. A., and Wilson, S. H. (2010) J. Biol. Chem. 285, 24457-24465
4. Nick McElhinny, S. A., and Ramsden, D. A. (2003) Mol. Cell Biol. 23, 2309-2315
5. Brown, J. A., Fiala, K. A., Fowler, J. D., Sherrer, S. M., Newmister, S. A., Duym, W. W., and Suo, Z. (2010) J. Mol. Biol. 395, 282-290
6. Graziewicz, M. A., Longley, M. J., and Copeland, W. C. (2006) Chem. Rev. 106, 383-405
7. Kaguni, L. S. (2004) Annu. Rev. Biochem. 73, 293-320
8. Yakubovskaya, E., Chen, Z., Carrodeguas, J. A., Kisker, C., and Bogenhagen, D. F. (2006) J. Biol. Chem. 281, 374-382
9. Lim, S. E., Longley, M. J., and Copeland, W. C. (1999) J. Biol. Chem. 274, 38197-38203
10. Brown, T. A., Cecconi, C., Tkachuk, A. N., Bustamante, C., and Clayton, D. A. (2005) Genes Dev. 19, 2466-2476
11. Shadel, G. S., and Clayton, D. A. (1997) Annu. Rev. Biochem. 66, 409-435
12. Bowmaker, M., Yang, M. Y., Yasukawa, T., Reyes, A., Jacobs, H. T., Huberman, J. A., and Holt, I. J. (2003) J. Biol. Chem. 278, 50961-50969
13. Cerritelli, S. M., Frolova, E. G., Feng, C., Grinberg, A., Love, P. E., and Crouch, R. J. (2003) Mol. Cell 11, 807-815
14. Gao, G., Orlova, M., Georgiadis, M. M., Hendrickson, W. A., and Goff, S. P. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 407-411
15. Astatke, M., Ng, K., Grindley, N. D., and Joyce, C. M. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 3402-3407
16. Yang, G., Franklin, M., Li, J., Lin, T. C., and Konigsberg, W. (2002) Biochemistry 41, 10256-10261
17. Bonnin, A., Lázaro, J. M., Blanco, L., and Salas, M. (1999) J. Mol. Biol. 290, 241-251
18. Boyer, P. L., Sarafianos, S. G., Arnold, E., and Hughes, S. H. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 3056-3061
19. Doublié, S., Tabor, S., Long, A. M., Richardson, C. C., and Ellenberger, T. (1998) Nature 391, 251-258
20. Lim, S. E., Ponamarev, M. V., Longley, M. J., and Copeland, W. C. (2003) J. Mol. Biol. 329, 45-57
21. Lee, Y. S., Kennedy, W. D., and Yin, Y. W. (2009) Cell 139, 312-324
22. Murakami, E., Feng, J. Y., Lee, H., Hanes, J., Johnson, K. A., and Anderson, K. S. (2003) J. Biol. Chem. 278, 36403-36409
23. Lee, H. R., and Johnson, K. A. (2007) J. Biol. Chem. 282, 31982-31989
24. Longley, M. J., Ropp, P. A., Lim, S. E., and Copeland, W. C. (1998) Biochemistry 37, 10529-10539
25. Kasiviswanathan, R., Longley, M. J., Young, M. J., and Copeland, W. C. (2010) Methods 51, 379-384
26. Longley, M. J., Clark, S., Yu Wai Man, C., Hudson, G., Durham, S. E., Taylor, R. W., Nightingale, S., Turnbull, D. M., Copeland, W. C., and Chinnery, P. F. (2006) Am. J. Hum. Genet. 78, 1026-1034
27. Yang, M. Y., Bowmaker, M., Reyes, A., Vergani, L., Angeli, P., Gringeri, E., Jacobs, H. T., and Holt, I. J. (2002) Cell 111, 495-505
28. Gallo, R. C., Yang, S. S., and Ting, R. C. (1970) Nature 228, 927-929
29. Mosbaugh, D. W. (1988) Nucleic Acids Res. 16, 5645-5659
30. Kornberg, A., and Baker, T. A. (1992) DNA Replication, 2nd Ed., p. 54, W.H. Freeman and Co., New York
31. Wheeler, L. J., and Mathews, C. K. (2011) J. Biol. Chem. 286, 16992-16996
32. Bourdon, A., Minai, L., Serre, V., Jais, J. P., Sarzi, E., Aubert, S., Chrétien, D., De Lonlay, P., Paquis-Flucklinger, V., Arakawa, H., Nakamura, Y., Munnich, A., and Rötig, A. (2007) Nat. Genet. 39, 776-780
33. Copeland, W. C. (2008) Annu. Rev. Med. 59, 131-146
34. Stumpf, J. D., Bailey, C. M., Spell, D., Stillwagon, M., Anderson, K. S., and Copeland, W. C. (2010) Hum. Mol. Genet. 19, 2123-2133
35. Clayton, D. A. (1982) Cell 28, 693-705
36. Wanrooij, S., Fusté, J. M., Farge, G., Shi, Y., Gustafsson, C. M., and Falkenberg, M. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 11122-11127
37. Fusté, J. M., Wanrooij, S., Jemt, E., Granycome, C. E., Cluett, T. J., Shi, Y., Atanassova, N., Holt, I. J., Gustafsson, C. M., and Falkenberg, M. (2010) Mol. Cell 37, 67-78
38. Astatke, M., Grindley, N. D., and Joyce, C. M. (1998) J. Mol. Biol. 278, 147-165
39. Polesky, A. H., Dahlberg, M. E., Benkovic, S. J., Grindley, N. D., and Joyce, C. M. (1992) J. Biol. Chem. 267, 8417-8428
40. Minnick, D. T., Bebenek, K., Osheroff, W. P., Turner, R. M., Jr., Astatke, M., Liu, L., Kunkel, T. A., and Joyce, C. M. (1999) J. Biol. Chem. 274, 3067-3075
41. Stumpf, J. D., and Copeland, W. C. (2011) Cell Mol. Life Sci. 68, 219-233
42. Wong, L. J., Naviaux, R. K., Brunetti-Pierri, N., Zhang, Q., Schmitt, E. S., Truong, C., Milone, M., Cohen, B. H., Wical, B., Ganesh, J., Basinger, A. A., Burton, B. K., Swoboda, K., Gilbert, D. L., Vanderver, A., Saneto, R. P., Maranda, B., Arnold, G., Abdenur, J. E., Waters, P. J., and Copeland, W. C. (2008) Hum. Mutat. 29, E150-E172
43. Spinazzola, A., Invernizzi, F., Carrara, F., Lamantea, E., Donati, A., Dirocco, M., Giordano, I., Meznaric-Petrusa, M., Baruffini, E., Ferrero, I., and Zeviani, M. (2009) J. Inherit. Metab. Dis. 32, 143-158
44. Copeland, W. C., Lam, N. K., and Wang, T. S. (1993) J. Biol. Chem. 268, 11041-11049