mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mt DNA in Saccharomyces cerevisiae

Human Molecular Genetics

Volumn 19, Issue 11, 2010, Pages 2123-2133

  Stumpf, Jeffrey D ^a   Bailey, Christopher M ^b   Spell, Diana ^a   Stillwagon, Matthew ^a   Anderson, Karen S ^b   Copeland, William C ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA; PROTEIN MIP1; RIBONUCLEOTIDE REDUCTASE; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE BETA; HISTIDINE; MIP1 PROTEIN, S CEREVISIAE; PRIMER DNA; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME INHIBITION; GENETIC ASSOCIATION; GENETIC MODEL; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL DNA REPLICATION; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; ONSET AGE; ORTHOLOGY; POINT MUTATION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; AGE; CHEMICAL STRUCTURE; CHEMISTRY; DNA REPLICATION; GENETICS; HUMAN; MUTATION; PHENOTYPE; PLASMID;

SACCHAROMYCES CEREVISIAE;

AGE FACTORS; DNA POLYMERASE I; DNA PRIMERS; DNA REPLICATION; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; HISTIDINE; HUMANS; MITOCHONDRIAL DISEASES; MODELS, MOLECULAR; MUTATION; PHENOTYPE; PLASMIDS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 77953499335     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq089     Document Type: Article

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