Pilot study examining the frequency of several gene polymorphisms involved in morphine pharmacodynamics and pharmacokinetics in a morbidly obese population

Obesity Surgery

Volumn 21, Issue 8, 2011, Pages 1257-1264

  Lloret Linares, Célia ^a,b   Hajj, Aline ^b,c   Poitou, Christine ^a,d   Simoneau, Guy ^b   Clement, Karine ^a,d   Laplanche, Jean Louis ^b,c   Lépine, Jean Pierre ^c   Bergmann, Jean François ^b   Mouly, Stéphane ^b,c   Peoc'h, Katell ^b,c  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b HÔPITAL LARIBOISIÈRE   (France)

^c INSERM   (France)

^d CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

ABCB1; Analgesia; COMT; Morphine; Obesity; OPRM1; Pharmacogenetics

Indexed keywords

MORPHINE;

ABCB1 GENE; ADULT; ANALGESIA; ANESTHESIA; ARTICLE; BODY MASS; CODON; COMT GENE; CONTROLLED STUDY; DISEASE SEVERITY; ETHNICITY; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBID OBESITY; OPRM1 GENE; PHARMACODYNAMICS; PILOT STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ANALGESICS, OPIOID; BODY MASS INDEX; CATECHOL O-METHYLTRANSFERASE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MORPHINE; OBESITY, MORBID; P-GLYCOPROTEIN; PARIS; PHARMACOGENETICS; PILOT PROJECTS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, OPIOID, MU; SEQUENCE ANALYSIS, DNA;

EID: 80052314519     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-010-0143-x     Document Type: Article

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