Association of a polymorphism of ABCB1 with obesity in Japanese individuals

Genomics

Volumn 91, Issue 6, 2008, Pages 512-516

  Ichihara, Sahoko ^a   Yamada, Yoshiji ^a   Kato, Kimihiko ^b   Hibino, Takeshi ^b   Yokoi, Kiyoshi ^b   Matsuo, Hitoshi ^c   Kojima, Tai ^c   Watanabe, Sachiro ^c   Metoki, Norifumi ^d   Yoshida, Hidemi ^e   Satoh, Kei ^e   Aoyagi, Yukitoshi ^f   Yasunaga, Akitomo ^f   Park, Hyuntae ^f   Tanaka, Masashi ^f   Nozawa, Yoshinori ^g  

^a MIE UNIVERSITY   (Japan)

^b GIFU PREFECTURAL TAJIMI HOSPITAL   (Japan)

^c GIFU PREFECTURAL GIFU HOSPITAL   (Japan)

^d Hirosaki Stroke Center   (Japan)

^e HIROSAKI UNIVERSITY   (Japan)

^f TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^g GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

Author keywords

ABCB1; Body mass index; Genetics; Obesity; Polymorphism

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN 1;

ADULT; AGED; ALLELE; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; OBESITY; PREVALENCE; PRIORITY JOURNAL;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BODY MASS INDEX; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; JAPAN; MALE; MIDDLE AGED; OBESITY; P-GLYCOPROTEIN; POLYMORPHISM, GENETIC; SEX FACTORS;

EID: 44649162377     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2008.03.004     Document Type: Article

References (35)

1. World Health Organization, September 2006. URL: http://www.who.int/mediacentre/factsheets/fs311/en/index.html.
2. Hubert H.B., Feinleib M., McNamara P.M., and Castelli W.P. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 67 (1983) 968-977
3. Shibata R., et al. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat. Med. 10 (2004) 1384-1389
4. Matsuzawa Y. Therapy insight: adipocytokines in metabolic syndrome and related cardiovascular disease. Nat. Clin. Pract. Cardiovasc. Med. 3 (2006) 35-42
5. Hill J.O., and Peters J.C. Environmental contributions to the obesity epidemic. Science 280 (1998) 1371-1374
6. Rankinen T., et al. The human obesity gene map: the 2005 update. Obesity (Silver Spring) 14 (2006) 529-644
7. Hager J., et al. A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10. Nat. Genet. 20 (1998) 304-308
8. Lee J.H., et al. Genome scan for human obesity and linkage to markers in 20q13. Am. J. Hum. Genet. 64 (1999) 196-209
9. Saar K., et al. Genome scan for childhood and adolescent obesity in German families. Pediatrics 111 (2003) 321-327
10. 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. N. Engl. J. Med. 333 (1995) 352-354
11. 3-adrenergic receptor polymorphisms are related to the onset of weight gain and blood pressure elevation over 5 years. Circulation 111 (2005) 3429-3434
12. Ristow M., Müller-Wieland D., Pfeiffer A., Krone W., and Kahn C.R. Obesity associated with a mutation in a genetic regulator of adipocyte differentiation. N. Engl. J. Med. 339 (1998) 953-959
13. Deeb S.S., et al. A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat. Genet. 20 (1998) 284-287
14. Scuteri A., et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 3 (2007) e115
15. Frayling T.M., et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316 (2007) 889-894
16. Dina C., et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat. Genet. 39 (2007) 724-726
17. Ichihara S., and Yamada Y. Genetic factors for human obesity. Cell. Mol. Life Sci. (2007) 10.1007/s00018-007-7453-8
18. Tanabe M., et al. Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J. Pharmacol. Exp. Ther. 297 (2001) 1137-1143
19. Cascorbi I. Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacol. Ther. 112 (2006) 457-473
20. Hoffmeyer S., et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 3473-3478
21. Hüebner C., et al. Triallelic single nucleotide polymorphisms and genotyping error in genetic epidemiology studies: MDR1 (ABCB1) G2677/T/A as an example. Cancer Epidemiol. Biomarkers Prev. 16 (2007) 1185-1192
22. Kimchi-Sarfaty C., et al. Ethnicity-related polymorphisms and haplotypes in the human ABCB1 gene. Pharmacogenomics 8 (2007) 29-39
23. Horinouchi M., et al. Significant genetic linkage of MDR1 polymorphisms at positions 3435 and 2677: functional relevance to pharmacokinetics of digoxin. Pharm. Res. 19 (2002) 1581-1585
24. Saito S., et al. Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population. J. Hum. Genet. 47 (2002) 38-50
25. Brant S.R., et al. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am. J. Hum. Genet. 73 (2003) 1282-1292
26. Eap C.B., et al. CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt. Hypertension 49 (2007) 1007-1014
27. Kim R.B., et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin. Pharmacol. Ther. 70 (2001) 189-199
28. Siegmund W., et al. The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol. Clin. Pharmacol. Ther. 72 (2002) 572-583
29. Heilbronn L.K. Association of - 3826 G variant in uncoupling protein-1 with increased BMI in overweight Australian women. Diabetologia 43 (2000) 242-244
30. 2-adrenoceptor gene polymorphism on obesity in males and in females. J. Intern. Med. 245 (1999) 253-259
31. Katzov H., et al. A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity. Hum. Mol. Genet. 13 (2004) 2647-2657
32. Kanazawa M., et al. Criteria and classification of obesity in Japan and Asia-Oceania. Asia Pac. J. Clin. Nutr. 11 (2002) S732-S737
33. Yamada Y., et al. Genetic factors for obesity. Int. J. Mol. Med. 18 (2006) 843-851
34. Itoh Y., et al. High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population. Immunogenetics 57 (2005) 717-729
35. Nakai K., et al. Highly multiplexed genotyping of coronary artery disease-associated SNPs using MALDI-TOF mass spectrometry. Hum. Mutat. 20 (2002) 133-138