Energetics of hydrogen bond switch, residue burial and cavity analysis reveals molecular basis of improved heparin binding to antithrombin

Journal of Biomolecular Structure and Dynamics

Volumn 29, Issue 2, 2011, Pages 339-350

  Singh, Poonam ^a   Singh, Khushboo ^b   Jairajpuri, Mohamad Aman ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^b AMITY UNIVERSITY   (India)

Author keywords

Accessible surface area; CASTp; DSSP; Glycosylation; PEARLS; Serine protease inhibitor

Indexed keywords

ALPHA ANTITHROMBIN III; ANTITHROMBIN III; BETA ANTITHROMBIN III; HEPARIN; ISOENZYME; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENERGY TRANSFER; ENZYME SPECIFICITY; HYDROGEN BOND; ISOENZYME ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN INTERACTION; RESIDUE ANALYSIS;

EID: 80052230208     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2011.10507389     Document Type: Article

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