Roles of N-Terminal Region Residues Lys11, Arg13, and Arg24 of Antithrombin in Heparin Recognition and in Promotion and Stabilization of the Heparin-Induced Conformational Change

Biochemistry

Volumn 43, Issue 3, 2004, Pages 675-683

  Schedin Weiss, Sophia ^a   Desai, Umesh R ^b,c   Bock, Susan C ^d   Olson, Steven T ^b   Björk, Ingemar ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; COAGULATION; CONFORMATIONS; PLASMAS; POLYSACCHARIDES; SUBSTITUTION REACTIONS; X RAY ANALYSIS;

MUTATIONS; X RAY STRUCTURES;

BIOCHEMISTRY;

AMINO ACID; ANTITHROMBIN; HEPARIN; PENTASACCHARIDE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CRYSTAL STRUCTURE; ENERGY TRANSFER; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; X RAY ANALYSIS;

ALANINE; AMINO ACID SUBSTITUTION; ANTITHROMBINS; ARGININE; ASPARTIC ACID; GLUTAMIC ACID; HEPARIN; HUMANS; IONS; KINETICS; LYSINE; OLIGOSACCHARIDES; PEPTIDE FRAGMENTS; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 1642453874     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi030173b     Document Type: Article

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