Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 Å and full insertion of the reactive center loop into β-sheet A

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 9, 1999, Pages 4808-4813

  Stratikos, Efstratios ^a   Gettins, Peter G W ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Fluorescence resonance energy transfer; Pittsburgh variant; Serpin covalent complex; 1 proteinase inhibitor

Indexed keywords

CYSTEINE; DANSYL CHLORIDE; PROTEINASE; SERINE PROTEINASE INHIBITOR; TRYPSIN; TRYPTOPHAN;

ARTICLE; CONFORMATION; CONFORMATIONAL TRANSITION; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE; PRIORITY JOURNAL;

ALPHA 1-ANTITRYPSIN; ANIMALS; FLUORESCENCE; PROTEIN BINDING; PROTEIN FOLDING; TRYPSIN;

EID: 0033608984     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.9.4808     Document Type: Article

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