Structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1L

Journal of Biological Chemistry

Volumn 286, Issue 35, 2011, Pages 30748-30758

  Yu, Eric ^a,b   Zhai, Dayong ^a   Jin, Chaofang ^a   Gerlic, Motti ^a   Reed, John C ^a   Liddington, Robert ^a  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; APOPTOSOMES; ATOMIC MODELS; BCL-2 FAMILY PROTEINS; CASPASE ACTIVATION; CASPASES; CELL-DEATH PATHWAYS; CYTOCHROME C; CYTOSOLS; HOST CELLS; HOST DEFENSE; INFECTED CELLS; MOLECULAR BASIS; MULTICELLULAR ORGANISMS; N-TERMINALS; PROGRAMMED CELL DEATHS; REVERSE ORIENTATION; STRUCTURAL DETERMINANTS; SUBSTRATE PEPTIDES; VACCINIA VIRUS; VIRAL INFECTIONS;

CELL DEATH; MITOCHONDRIA; OLIGOMERS; VIRUSES;

PROTEINS;

APOPTOSOME; CASPASE 3; CASPASE 7; CASPASE 9; PROTEIN F1L; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTALLIZATION; DIMERIZATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN METABOLISM; PROTEIN MOTIF; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; VACCINIA VIRUS;

AMINO ACID SEQUENCE; APOPTOSIS; CASPASE 9; CELL DEATH; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PEPTIDES; PLASMIDS; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; VACCINIA VIRUS; VIRAL PROTEINS;

VACCINIA VIRUS;

EID: 80052216444     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.280149     Document Type: Article

References (52)

1. Benedict, C. A., Norris, P. S., and Ware, C. F. (2002) Nat. Immunol. 3, 1013-1018
2. Cuconati, A., and White, E. (2002) Genes Dev. 16, 2465-2478
3. Galluzzi, L., Brenner, C., Morselli, E., Touat, Z., and Kroemer, G. (2008) PLoS Pathog. 4, e1000018
4. Creagh, E. M., Conroy, H., and Martin, S. J. (2003) Immunol. Rev. 193, 10-21
5. Youle, R. J., and Strasser, A. (2008) Nat. Rev. Mol. Cell Biol. 9, 47-59
6. Kroemer, G., Galluzzi, L., and Brenner, C. (2007) Physiol. Rev. 87, 99-163
7. Bratton, S. B., Walker, G., Srinivasula, S. M., Sun, X. M., Butterworth, M., Alnemri, E. S., and Cohen, G. M. (2001) EMBO J. 20, 998-1009
8. Yuan, S., Yu, X., Topf, M., Ludtke, S. J., Wang, X., and Akey, C. W. (2010) Structure 18, 571-583
9. Renatus, M., Stennicke, H. R., Scott, F. L., Liddington, R. C., and Salvesen, G. S. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 14250-14255
10. Pop, C., Timmer, J., Sperandio, S., and Salvesen, G. S. (2006) Mol. Cell 22, 269-275
11. Liu, X., Kim, C. N., Yang, J., Jemmerson, R., and Wang, X. (1996) Cell 86, 147-157
12. Zou, H., Henzel, W. J., Liu, X., Lutschg, A., and Wang, X. (1997) Cell 90, 405-413
13. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cell 91, 479-489
14. Du, C., Fang, M., Li, Y., Li, L., and Wang, X. (2000) Cell 102, 33-42
15. Verhagen, A. M., Ekert, P. G., Pakusch, M., Silke, J., Connolly, L. M., Reid, G. E., Moritz, R. L., Simpson, R. J., and Vaux, D. L. (2000) Cell 102, 43-53
16. Malladi, S., Challa-Malladi, M., Fearnhead, H. O., and Bratton, S. B. (2009) EMBO J. 28, 1916-1925
17. Postigo, A., and Ferrer, P. E. (2009) Microbes Infect. 11, 1071-1078
18. Kvansakul, M., Yang, H., Fairlie, W. D., Czabotar, P. E., Fischer, S. F., Perugini, M. A., Huang, D. C., and Colman, P. M. (2008) Cell Death Differ. 15, 1564-1571
19. Kvansakul, M., van Delft, M. F., Lee, E. F., Gulbis, J. M., Fairlie, W. D., Huang, D. C., and Colman, P. M. (2007) Mol. Cell 25, 933-942
20. Aoyagi, M., Zhai, D., Jin, C., Aleshin, A. E., Stec, B., Reed, J. C., and Liddington, R. C. (2007) Protein Sci. 16, 118-124
21. Douglas, A. E., Corbett, K. D., Berger, J. M., McFadden, G., and Handel, T. M. (2007) Protein Sci. 16, 695-703
22. Cooray, S., Bahar, M. W., Abrescia, N. G., McVey, C. E., Bartlett, N. W., Chen, R. A., Stuart, D. I., Grimes, J. M., and Smith, G. L. (2007) J. Gen. Virol. 88, 1656-1666
23. Huang, Q., Petros, A. M., Virgin, H. W., Fesik, S. W., and Olejniczak, E. T. (2003) J. Mol. Biol. 332, 1123-1130
24. Huang, Q., Petros, A. M., Virgin, H. W., Fesik, S. W., and Olejniczak, E. T. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 3428-3433
25. Best, S. M. (2008) Annu. Rev. Microbiol. 62, 171-192
26. Wasilenko, S. T., Stewart, T. L., Meyers, A. F., and Barry, M. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 14345-14350
27. Stewart, T. L., Wasilenko, S. T., and Barry, M. (2005) J. Virol. 79, 1084-1098
28. Wasilenko, S. T., Banadyga, L., Bond, D., and Barry, M. (2005) J. Virol. 79, 14031-14043
29. Taylor, J. M., Quilty, D., Banadyga, L., and Barry, M. (2006) J. Biol. Chem. 281, 39728-39739
30. Campbell, S., Hazes, B., Kvansakul, M., Colman, P., and Barry, M. (2010) J. Biol. Chem. 285, 4695-4708
31. Postigo, A., Cross, J. R., Downward, J., and Way, M. (2006) Cell Death Differ. 13, 1651-1662
32. Zhai, D., Yu, E., Jin, C., Welsh, K., Shiau, C. W., Chen, L., Salvesen, G. S., Liddington, R., and Reed, J. C. (2010) J. Biol. Chem. 285, 5569-5580
33. Kim, H. E., Du, F., Fang, M., and Wang, X. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 17545-17550
34. Riedl, S. J., Renatus, M., Snipas, S. J., and Salvesen, G. S. (2001) Biochemistry 40, 13274-13280
35. Shiozaki, E. N., Chai, J., Rigotti, D. J., Riedl, S. J., Li, P., Srinivasula, S. M., Alnemri, E. S., Fairman, R., and Shi, Y. (2003) Mol. Cell 11, 519-527
36. Chao, Y., Shiozaki, E. N., Srinivasula, S. M., Rigotti, D. J., Fairman, R., and Shi, Y. (2005) PLoS Biol. 3, e183
37. Faustin, B., Chen, Y., Zhai, D., Le Negrate, G., Lartigue, L., Satterthwait, A., and Reed, J. C. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 3935-3940
38. Tovchigrechko, A., and Vakser, I. A. (2006) Nucleic Acids Res. 34, W310-W314
39. Wiehe, K., Pierce, B., Tong, W. W., Hwang, H., Mintseris, J., and Weng, Z. (2007) Proteins 69, 719-725
40. Riedl, S. J., Renatus, M., Schwarzenbacher, R., Zhou, Q., Sun, C., Fesik, S. W., Liddington, R. C., and Salvesen, G. S. (2001) Cell 104, 791-800
41. Mashiach, E., Schneidman-Duhovny, D., Andrusier, N., Nussinov, R., and Wolfson, H. J. (2008) Nucleic Acids Res. 36, W229-W232
42. Rost, B. (1996) Methods Enzymol. 266, 525-539
43. Komiyama, T., Ray, C. A., Pickup, D. J., Howard, A. D., Thornberry, N. A., Peterson, E. P., and Salvesen, G. (1994) J. Biol. Chem. 269, 19331-19337
44. dela Cruz, W. P., Friesen, P. D., and Fisher, A. J. (2001) J. Biol. Chem. 276, 32933-32939
45. Fisher, A. J., Cruz, W., Zoog, S. J., Schneider, C. L., and Friesen, P. D. (1999) EMBO J. 18, 2031-2039
46. Xu, G., Cirilli, M., Huang, Y., Rich, R. L., Myszka, D. G., and Wu, H. (2001) Nature 410, 494-497
47. Deveraux, Q. L., Leo, E., Stennicke, H. R., Welsh, K., Salvesen, G. S., and Reed, J. C. (1999) EMBO J. 18, 5242-5251
48. Scott, F. L., Denault, J. B., Riedl, S. J., Shin, H., Renatus, M., and Salvesen, G. S. (2005) EMBO J. 24, 645-655
49. Chai, J., Shiozaki, E., Srinivasula, S. M., Wu, Q., Datta, P., Alnemri, E. S., Shi, Y., and Dataa, P. (2001) Cell 104, 769-780
50. Huang, Y., Park, Y. C., Rich, R. L., Segal, D., Myszka, D. G., and Wu, H. (2001) Cell 104, 781-790
51. Sun, C., Cai, M., Gunasekera, A. H., Meadows, R. P., Wang, H., Chen, J., Zhang, H., Wu, W., Xu, N., Ng, S. C., and Fesik, S. W. (1999) Nature 401, 818-822
52. Pop, C., and Salvesen, G. S. (2009) J. Biol. Chem. 284, 21777-21781