XPF-dependent DNA breaks and RNA polymerase II arrest induced by antitumor DNA interstrand crosslinking-mimetic alkaloids

Chemistry and Biology

Volumn 18, Issue 8, 2011, Pages 988-999

  Feuerhahn, Sascha ^a   Giraudon, Christophe ^a   Martínez Díez, Marta ^b   Bueren Calabuig, Juan A ^c   Galmarini, Carlos M ^b   Gago, Federico ^c   Egly, Jean Marc ^a,d  

^a INSERM   (France)

^b PHARMAMAR S A   (Spain)

^c UNIVERSITY OF ALCALÁ   (Spain)

^d IRCAD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; ALKYLATING AGENT; ANTINEOPLASTIC AGENT; CROSS LINKING REAGENT; DEOXYRIBONUCLEASE I; DNA; DNA BINDING PROTEIN; ENDONUCLEASE; ERCC1 PROTEIN, HUMAN; RNA POLYMERASE II; TETRAHYDROISOQUINOLINE DERIVATIVE; TRABECTEDIN; TRANSCRIPTION FACTOR SP1; XERODERMA PIGMENTOSUM GROUP F PROTEIN; ZALYPSIS;

ARTICLE; CHEMICAL STRUCTURE; DNA STRAND BREAKAGE; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; TRANSCRIPTION INITIATION;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; CROSS-LINKING REAGENTS; DEOXYRIBONUCLEASE I; DIOXOLES; DNA; DNA BREAKS; DNA-BINDING PROTEINS; ENDONUCLEASES; HUMANS; MODELS, MOLECULAR; RNA POLYMERASE II; SP1 TRANSCRIPTION FACTOR; TETRAHYDROISOQUINOLINES; TRANSCRIPTIONAL ACTIVATION;

EID: 80052167125     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.06.007     Document Type: Article

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