The influence of chemotherapy on taste perception and food hedonics: A systematic review

Cancer Treatment Reviews

Volumn 38, Issue 2, 2012, Pages 152-163

  Boltong, Anna ^a   Keast, Russell ^b  

^a THE UNIVERSITY OF MELBOURNE   (Australia)

^b DEAKIN UNIVERSITY   (Australia)

Author keywords

Appetite; Cancer; Chemotherapy; Flavor; Hedonics; Liking; Taste changes

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CAPECITABINE; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUDARABINE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; MELPHALAN; METHOTREXATE; NAVELBINE; PACLITAXEL; PEMETREXED; PREDNISOLONE; TAMOXIFEN; TENIPOSIDE; VINCRISTINE; VINDESINE;

APPETITE; BITTER TASTE; BREAST CANCER; CANCER CHEMOTHERAPY; CHRONIC LYMPHATIC LEUKEMIA; COLON CANCER; DECREASED APPETITE; DIET; DRUG EFFICACY; FOOD AVERSION; FOOD INTAKE; FOOD PREFERENCE; GLIOMA; HODGKIN DISEASE; HUMAN; LUNG CANCER; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MELANOMA; MESOTHELIOMA; NAUSEA; NONHODGKIN LYMPHOMA; NUTRITIONAL ASSESSMENT; OVARY CANCER; PROSTATE CANCER; REVIEW; STOMACH CANCER; SWEETNESS; SYSTEMATIC REVIEW; TASTE; TASTE ACUITY; TASTE PREFERENCE; VISUAL ANALOG SCALE;

ANTINEOPLASTIC AGENTS; APPETITE; FOOD HABITS; HUMANS; TASTE PERCEPTION;

EID: 80051842062     PISSN: 03057372     EISSN: 15321967     Source Type: Journal    
DOI: 10.1016/j.ctrv.2011.04.008     Document Type: Review

References (91)

1. Keast R. Flavor interactions at the sensory level. Flavour perception 2004, 228-254. Blackwell Publishing, United Kingdom. A.J. Taylor, D.D. Roberts (Eds.).
2. Green B.G. Studying taste as a cutaneous sense. Food Qual Pref 2003, 14(2):99-109.
3. Breslin P.A., Spector A.C. Mammalian taste perception. Curr Biol 2008, 18(4):R148-R155.
4. Duffy V., Fast K., Lucchina L., Bartoshuk L. Oral sensation and cancer. Principles and practice of palliative care and Supportive Oncology 2002, 78-193. Lippincott Williams & Wilkins, Philadelphia. 2nd ed. A. Berger, R. Portenoy, D. Weissman (Eds.).
5. Hong J.H., Omur-Ozbek P., Stanek B.T., Dietrich A.M., Duncan S.E., Lee Y.W., et al. Taste and odor abnormalities in cancer patients. J Support Oncol 2009, 7(2):58-65.
6. Epstein J., Hong C., Logan R., Barasch A., Gordon S., Oberlee-Edwards L., et al. A systematic review of orofacial pain in patients receiving cancer therapy. Support Care Cancer 2010, 18(8):1023-1031.
7. Ruo Redda M.G., Allis S. Radiotherapy-induced taste impairment. Cancer Treat Rev 2006, 32:541-547.
8. Comeau T.B., Epstein J.B., Migas C. Taste and smell dysfunction in patients receiving chemotherapy: a review of current knowledge. Support Care Cancer 2001, 9(8):575-580.
9. Peregrin T. Improving taste sensation in patients who have undergone chemotherapy or radiation therapy. J Am Diet Assoc 2006, 106(10):1536-1540.
10. Strasser F., Demmer R., Bohme C., Schmitz S.-F.H., Thuerlimann B., Cerny T., et al. Prevention of docetaxel- or paclitaxel-associated taste alterations in cancer patients with oral glutamine: a randomized, placebo-controlled, double-blind study. Oncologist 2008, 13(3):337-346.
11. Doty R.L., Shah M., Bromley S.M. Drug-induced taste disorders. Drug Saf 2008, 31(3):199-215.
12. Schiffman S.S. Critical illness and changes in sensory perception. Proc Nutr Soc 2007, 66(3):331-345.
13. Bernhardson B.M., Tishelman C., Rutqvist L.E. Self-reported taste and smell changes during cancer chemotherapy. Support Care Cancer 2008, 16(3):275-283.
14. Bernhardson B. 5 themes described the experiences of patients with chemotherapy induced oral mucositis. Evid Based Nurs 2003, 6(2):62.
15. Bernhardson B.M., Tishelman C., Rutqvist L.E. Chemosensory changes experienced by patients undergoing cancer chemotherapy: a qualitative interview study. J Pain Symptom Manage 2007, 34(4):403-412.
16. Schiffman S.S., Sattely-Miller E.A., Taylor E.L., Graham B.G., Landerman L.R., Zervakis J., et al. Combination of flavor enhancement and chemosensory education improves nutritional status in older cancer patients. J Nutr Health Aging 2007, 11(5):439-454.
17. Wickham R.S., Rehwaldt M., Kefer C., Shott S., Abbas K., Glynn-Tucker E., et al. Taste changes experienced by patients receiving chemotherapy. Oncol Nurs Forum 1999, 26(4):697-706.
18. Chandrashekar J., Hoon M.A., Ryba N.J.P., Zuker C.S. The receptors and cells for mammalian taste. Nature 2006, 444(7117):288-294.
19. Beebe-Center J.G. The psychology of pleasantness and unpleasantness 1932, Von Nostrand, New Jersey.
20. Kahneman D., Diener E., Shwarz N. Well-Being: The foundations of hedonic psychology 2003, Russell Sage Foundation, New York.
21. Mela D.J. Eating for pleasure or just wanting to eat? Reconsidering sensory hedonic responses as a driver of obesity. Appetite 2006, 47(1):10-17.
22. Bernstein I.L., Webster M.M., Bernstein I.D. Food aversions in children receiving chemotherapy for cancer. Cancer 1982, 50(12):2961-2963.
23. Berridge K.C., Robinson T.E., Aldridge J.W. Dissecting components of reward: 'liking', 'wanting', and learning. Curr Opin Pharmacol 2009, 9(1):65-73.
24. Bernstein I.L. Learned taste aversions in children receiving chemotherapy. Science 1978, 200(4347):1302-1303.
25. Garb J.L., Stunkard A.J. Taste aversions in man. Am J Psychiatry 1974, 131(11):1204-1207.
26. Blundell J.E. Hunger, appetite and satiety-constructs in search of identities. Nutrition and lifestyles 1979, Applied Science Publishers, London. M. Turner (Ed.).
27. Lawless H.T., Heymann H. Sensory evaluation of food: principles and practices 1998, Chapman & Hall, New York.
28. Ng K., Woo J., Kwan M., Sea M., Wang A., Lo R., et al. Effect of age and disease on taste perception. J Pain Symptom Manage 2004, 28(1):28-34.
29. Hayes J.E., Bartoshuk L.M., Kidd J.R., Duffy V.B. Supertasting and PROP bitterness depends on more than the TAS2R38 gene. Chem Senses 2008, 33(3):255-265.
30. Schiffman S.S. Perception of taste and smell in elderly persons. Crit Rev Food Sci Nutr 1993, 33(1):17-26.
31. Ogama N., Suzuki S., Umeshita K., Kobayashi T., Kaneko S., Kato S., et al. Appetite and adverse effects associated with radiation therapy in patients with head and neck cancer. Eur J Oncol Nurs 2010, 14(1):3-10.
32. Chen Q.-Y., Alarcon S., Tharp A., Ahmed O.M., Estrella N.L., Greene T.A., et al. Perceptual variation in umami taste and polymorphisms in TAS1R taste receptor genes. Am J Clin Nutr 2009, 90(3):770S-779S.
33. Fushan A.A., Simons C.T., Slack J.P., Manichaikul A., Drayna D. Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose. Curr Biol 2009, 19(15):1288-1293.
34. Hayes J.E., Wallace M.R., Knopik V.S., Herbstman D.M., Bartoshuk L.M., Duffy V.B. Allelic variation in TAS2R bitter receptor genes associates with variation in sensations from and ingestive behaviors toward common bitter beverages in adults. Chem Senses 2011, 36(3):311-319.
35. Keast R.S., Bournazel M.M., Breslin P.A. A psychophysical investigation of binary bitter-compound interactions. Chem Senses 2003, 28(4):301-313.
36. Lucas L., Riddell L., Liem G., Whitelock S., Keast R. The influence of sodium on liking and consumption of salty food. J Food Sci 2011, 76(1):S72-S76.
37. Keast R.S., Roper J. A complex relationship among chemical concentration, detection threshold, and suprathreshold intensity of bitter compounds. Chem Senses 2007, 32(3):245-253.
38. Bartoshuk L.M., Fast K., Snyder D.J. Differences in our sensory worlds. Curr DirPsychol Sci 2005, 122-125.
39. Bartoshuk L.M., Duffy V.B., Chapo A.K., Fast K., Yiee J.H., Hoffman H.J., et al. From psychophysics to the clinic: missteps and advances. Food Qual Pref 2004, 15(7-8):617-632.
40. Gibson J.J. The senses considered as perceptual systems 1966, Houghton Mifflin, Boston.
41. Rozin P. " Taste-smell confusions" and the duality of the olfactory sense. Percept Psychophys 1982, 31(4):397-401.
42. Clark C.C., Lawless H.T. Limiting response alternatives in time-intensity scaling: an examination of the halo-dumping effect. Chem Senses 1994, 19(6):583-594.
43. Lawless H.T., Sinopoli D., Chapman K.W. A comparison of the labelled affective magnitude scale and the 9-point hedonic scale and examination of categorical behaviour. J Sens Stud 2010, 25:54-66.
44. Peryam GRG, Girardot NF. Advanced taste-test method. Food Engineering 1952;24(7).
45. Aaronson N.K., Ahmedzai S., Bergman B., Bullinger M., Cull A., Duez N.J., et al. The European Organization for Research and Treatment of Cancer QLQ-C30 - a quality of life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993, 85(5):365-376.
46. Cleeland C.S., Mendoza T.R., Wang X.S., Chou C., Harle M.T., Morrissey M., et al. Assessing symptom distress in cancer patients. Cancer 2000, 89(7):1634-1646.
47. DeHaes J.C.M.J., Vanknippenberg F.C.E., Neijt J.P. Measuring psychological and physical distress in caner patients - structure and application of the Rotterdam Symptom Checklist. Br J Cancer 1990, 62(6):1034-1038.
48. Green B., Lawless H. The psychophysics of somatosensory chemoreception in the nose and mouth. Smell and taste in health and disease 1991, 235-253. Raven Press, New York. T. Getchall, R. Doty, L. Bartoshuk, J. Snow (Eds.).
49. Hovan A., Williams P., Stevenson-Moore P., Wahlin Y., Ohrn K., Elting L., et al. A systematic review of dysgeusia induced by cancer therapies. Supp Care Cancer 2010, 18(8):1081-1087.
50. Boltong A., Keast R., Aranda S. A matter of taste: making the distinction between taste and flavor is essential for improving management of dysgeusia. Supp Care Cancer 2011, 19(4):441-442.
51. Maes A., Huygh I., Weltens C., Vandevelde G., Delaere P., Evers G., et al. De Gustibus: time scale of loss and recovery of tastes caused by radiotherapy. Radiother Oncol 2002, 63(2):195-201.
52. Rosenthal D.I., Mendoza T.R., Chambers M.S., Asper J.A., Gning I., Kies M.S., et al. Measuring head and neck cancer symptom burden: the development and validation of the M.D. Anderson symptom inventory, head and neck module. Head Neck 2007, 29(10):923-931.
53. Sandow P.L. Taste loss and recovery following radiation therapy. J Dent Res 2006, 85(7):608.
54. Skolin I., Hernell O., Wahlin Y.B. Energy and nutrient intake and nutritional status of children with malignant disease during chemotherapy after the introduction of new mealtime routines. Scand J Caring Sci 2001, 15(1):82-91.
55. PHRU. Critical Appraisal Skills Programme. Oxford: UK National Health Service 2007:Downloadable tools series. Downloadable tools series. [cited 2009 December 1, 2009]. http://www.phru.nhs.uk/pages/phd/resources.htm.
56. Fayers PM AN, Bjordal K, Groenvold M, Curran D, Bottomley A. The EORTC QLQ-C30 Scoring Manual, 3rd ed. Brussells: European Organisation for Research and Treatment of Cancer; 2001.
57. Steinbach S., Hummel T., Bohner C., Berktold S., Hundt W., Kriner M., et al. Qualitative and quantitative assessment of taste and smell changes in patients undergoing chemotherapy for breast cancer or gynecologic malignancies. J Clin Oncol 2009, 27(11):1899-1905.
58. Eichhorst B.F., Busch R., Obwandner T., Kuhn-Hallek I., Herschbach P., Hallek M. Health-related quality of life in younger patients with chronic lymphocytic leukemia treated with fludarabine plus cyclophosphamide or fludarabine alone for first-line therapy: a study by the German CLL Study Group. J Clin Oncol 2007, 25(13):1722-1731.
59. Grindel CMG. The effects of chemotherapy and disease on the nutritional patterns of breast cancer women during the first six months of treatment. Unpublished PhD thesis. University of Maryland, Baltimore; 1988.
60. Hurny C., Bernhard J., Coates A.S., Castiglione-Gertsch M., Peterson H.F., Gelber R.D., et al. Impact of adjuvant therapy on quality of life in women with node-positive operable breast cancer [corrected] [published erratum appears in Lancet 1997 Jul 26; 350(9073): 298]. Lancet 1996, 347(9011):1279-1284.
61. Park S.H., Lee W.K., Chung M., Bang S.M., Cho E.K., Lee J.H., et al. Quality of life in patients with advanced gastric cancer treated with second-line chemotherapy. Cancer Chemother Pharmacol 2006, 57(3):289-294.
62. Carson J.A., Gormican A. Taste acuity and food attitudes of selected patients with cancer. J Am Diet Assoc 1977, 70(4):361-365.
63. Ovesen L., Hannibal J., Sorensen M. Taste thresholds in patients with small-cell lung cancer. J Cancer Res Clin Oncol 1991, 117(1):70-72.
64. Bruera E., Carraro S., Roca E., Cedaro L., Chacon R. Association between malnutrition and caloric intake, emesis, psychological depression, glucose taste, and tumor mass. Cancer Treat Rep 1984, 68(6):873-876.
65. Andrykowski M.A., Otis M.L. Development of learned food aversions in humans: Investigation in a 'natural laboratory' of cancer chemotherapy. Appetite 1990, 14(2):145-158.
66. Jacobsen P.B., Bovbjerg D.H., Schwartz M.D., Andrykowski M.A. Formation of food aversions in cancer patients receiving repeated infusions of chemotherapy. Behav Res Ther 1993, 31(8):739-748.
67. Mattes R.D., Arnold C., Boraas M. Learned food aversions among cancer chemotherapy patients. Incidence, nature, and clinical implications. Cancer 1987, 60(10):2576-2580.
68. Mattes R.D., Curran W.J., Alavi J., Powlis W., Whittington R. Clinical implications of learned food aversions in patients with cancer treated with chemotherapy or radiation therapy. Cancer 1992, 70(1):192-200.
69. Boakes R.A., Tarrier N., Barnes B.W., Tattersall M.H. Prevalence of anticipatory nausea and other side-effects in cancer patients receiving chemotherapy. Eur J Cancer 1993, 29A(6):866-870.
70. Holmes S. Food avoidance in patients undergoing cancer chemotherapy. Support Care Cancer 1993, 1(6):326-330.
71. Andresen G.V. Conditioned food aversions in cancer chemotherapy 1990, ProQuest Information & Learning, US.
72. Bernstein I.L., Webster M.M. Learned taste aversions in humans. Physiol Behav 1980, 25(3):363-366.
73. Mattes R.D., Arnold C., Boraas M. Management of learned food aversions in cancer patients receiving chemotherapy. Cancer Treat Rep 1987, 71(11):1071-1078.
74. Schwartz M.D., Jacobsen P.B., Bovbjerg D.H. Role of nausea in the development of aversions to a beverage paired with chemotherapy treatment in cancer patients. Physiol Behav 1996, 59(4-5):659-663.
75. Trant A.S., Serin J., Douglass H.O. Is taste related to anorexia in cancer patients?. Am J Clin Nutr 1982, 36(1):45-58.
76. Gebbia V., Gridelli C., Verusio C., Frontini L., Aitini E., Daniele B., et al. Weekly docetaxel vs. docetaxel-based combination chemotherapy as second-line treatment of advanced non-small-cell lung cancer patients. The DISTAL-2 randomized trial. Lung Cancer 2009, 63(2):251-258.
77. Giaccone G., Splinter T.A., Debruyne C., Kho G.S., Lianes P., van Zandwijk N., et al. Randomized study of paclitaxel-cisplatin versus cisplatin-teniposide in patients with advanced non-small-cell lung cancer. The European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group. J Clin Oncol 1998, 16(6):2133-2141.
78. Greimel E.R., Bjelic-Radisic V., Pfisterer J., Hilpert F., Daghofer F., du Bois A. Randomized study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group comparing quality of life in patients with ovarian cancer treated with cisplatin/paclitaxel versus carboplatin/paclitaxel. J Clin Oncol 2006, 24(4):579-586.
79. Gridelli C., Gallo C., Shepherd F.A., Illiano A., Piantedosi F., Robbiati S.F., et al. Gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer: a phase III trial of the Italian GEMVIN Investigators and the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2003, 21(16):3025-3034.
80. Helbekkmo N., Strom H.H., Sundstrom S.H., Aasebo U., Von Plessen C., Bremnes R.M. Chemotherapy and quality of life in NSCLC PS 2 patients. Acta Oncol 2009, 48(7):1019-1025.
81. ten Bokkel Huinink W.W., Bergman B., Chemaissani A., Dornoff W., Drings P., Kellokumpu-Lehtinen P.L., et al. Single-agent gemcitabine: an active and better tolerated alternative to standard cisplatin-based chemotherapy in locally advanced or metastatic non-small cell lung cancer. Lung Cancer 1999, 26(2):85-94.
82. Coates A., Gebski V., Bishop J.F., Jeal P.N., Woods R.L., Snyder R., et al. Improving the quality of life during chemotherapy for advanced breast cancer. A comparison of intermittent and continuous treatment strategies. N Engl J Med 1987, 317(24):1490-1495.
83. Smith J.L., Malinauskas B.M., Garner K.J., Barber-Heidal K. Factors contributing to weight loss, nutrition-related concerns and advice received by adults undergoing cancer treatment. Adv Med Sci 2008, 53(2):198-204.
84. Glimelius B., Birgegard G., Hoffman K., Hagnebo C., Hogman G., Kvale G., et al. Improved care of patients with small cell lung cancer. Nutritional and quality of life aspects. Acta Oncol 1992, 31(8):823-831.
85. Greimel E.R., Winter R., Kapp K.S., Haas J. Quality of life and sexual functioning after cervical cancer treatment: a long-term follow-up study. Psycho-Oncology 2009, 18(5):476-482.
86. Sanchez-Lara K., Sosa-Sanchez R., Green-Renner D., Rodriguez C., Laviano A., Motola-Kuba D., et al. Influence of taste disorders on dietary behaviors in cancer patients under chemotherapy. Nutr J 2010, 9:15.
87. Bauer JC, S. Intensive nutrition intervention improves outcomes in patients with cancer cachexia receiving chemotherapy - a pilot study. Support Care Cancer 2005;13:270-74.
88. Bartoshuk L.M. Chemosensory alterations and cancer therapies. NCI Monogr 1990, (9):179-184.
89. Nielsen S.S., Theologides A., Vickers Z.M. Influence of food odors on food aversions and preferences in patients with cancer. Am J Clin Nutr 1980, 33(11):2253-2261.
90. Mulder N.H., Smit J.M., Kreumer W.M.I., Bouman J., Sleijfer D.T., Veeger W., et al. Effect of chemotherapy on taste sensation in patients with disseminated malignant melanoma. Oncology 1983, 40:36-38.
91. Hollen P.J., Gralla R.J., Liepa A.M., Symanowski J.T., Rusthoven J.J. Adapting the lung cancer symptom scale (LCSS) to mesothelioma. Cancer 2004, 101:587-595.