Structural effects of carbohydrate-containing polycations on gene delivery. 3. Cyclodextrin type and functionalization

Bioconjugate Chemistry

Volumn 14, Issue 3, 2003, Pages 672-678

  Popielarski, Stephen R ^a   Mishra, Swaroop ^a   Davis, Mark E ^a  

^a California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOMOLECULES; CYCLODEXTRINS; DNA; GENE TRANSFER; GENES; HYDROPHILICITY; TOXICITY;

CATIONIC Β-CYCLODEXTRIN; DIMETHYL SUBERIMIDATE; FUNCTIONALIZATIONS; GENE DELIVERY; PLASMID DNA; POLYCATIONS; POLYPLEXES; PRIMARY AMINES; STRUCTURAL EFFECT; Γ-CD;

MONOMERS;

3A,3B DIDEOXY 3A,3B DIAMINO BETA CYCLODEXTRIN; 3A,3B DIDEOXY 3A,3B DIAMINO GAMMA CYCLODEXTRIN; 6A,6D DIDEOXY 6A,6D DIAMINO BETA CYCLODEXTRIN; CARBOHYDRATE; CYCLODEXTRIN; DIAMINE; GAMMA CYCLODEXTRIN; PLASMID DNA; POLYCATION; POLYMER; SUBERIMIDIC ACID DIMETHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN BHK; GENE TARGETING; HYDROPHILICITY; MOLECULAR WEIGHT; NONHUMAN; POLYMERIZATION;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0037570835     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc034010b     Document Type: Article

References (20)

1. Jeong, J. H., Song, S. H., Lim, D. W., Lee, H., and Park, T. G. (2001) DNA transfection using linear poly(ethylenimine) prepared by controlled acid hydrolysis of poly(2-ethyl-2-oxazoline). J. Controlled Release 73, 391-399.
2. Godbey, W. T., Wu, K. K., and Mikos, A. G. (1999) Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J. Biomed. Mater. Res. 45, 268-275.
3. Remy, J.-S., Abdallah, P., Zanta, M. A., Boussif, O., Behr, J.-P., and Demeneix, B. (1998) Gene transfer with lipospermines and polyethylenimines. Adv. Drug Deliv. Rev. 30, 85-95.
4. Fischer, D., von Harpe, A., Kunath, K., Petersen, H., Li, Y., and Kissel, T. (2002) Copolymers of ethylene imine and N-(2- hydroxyethyl)-ethylene imine as tools to study effects of polymer structure on physicochemical and biological properties of DNA complexes. Bioconjugate Chem. 13, 1124-1133.
5. Petersen, H., Fechner, P. M., Martin, A. L., Kunath, K., Stolnik, S., Roberts, C. J., Fischer, D., Davies, M. C., and Kissel, T. (2002) Polyethylenimine-graft-poly(ethylene glycol) copolymers: Influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. Bioconjugate Chem. 13, 845-854.
6. Kircheis, R., Wightman, L., and Wagner E. (2001) Design and gene delivery activity of modified polyethylenimines. Adv. Drug Deliv. Rev. 53, 341-358.
7. Zelikin, A. N., and Izumrudov, V. A. (2002) Polyelectrolyte complexes formed by calf thymus DNA and aliphatic ionenes: Unexpected change in stability upon variation of chain length of ionenes of different charge density. Macromol. Biosci. 2, 78-81.
8. Zelikin, A. N., Putnam, D., Shastri, P., Langer, R., and Izumrudov, V. A. (2002) Aliphatic ionenes as gene delivery agents: Elucidation of structure-function relationship through modification of charge density and polymer length. Bioconjugate Chem. 13, 548-553.
9. Köping-Höggård, M., Tubulekas, I., Guan, H., Edwards, K., Nilsson, M., Vårum, K. M., and Artursson, P. (2001) Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. Gene Therapy 8, 1108-1121.
10. Ohsaki, M., Okuda, T., Wada, A., Hirayama, T., Niidome, T., and Aoyagi, H. (2002) In vitro gene transfection using dendritic poly(L-lysine). Bioconjugate Chem. 13, 510-517.
11. Jones, N. A., Hill, I. R. C., Stolnik, S., Bignotti, F., Davis, S. S., and Garnett, M. C. (2000) Polymer chemical structure is a key determinant of physicochemical and colloidal properties of polymer-DNA complexes for gene delivery. BBA - Gene Struct. Expr. 1517, 1-18.
12. Azzam, T., Eliyahu, H., Shapira, L., Linial, M., Barenholz, Y., and Domb, A. J. (2002) Polysaccharide-oligoamine based conjugates for gene delivery. J. Med. Chem. 45, 1817-1824.
13. Gonzalez, H., Hwang, S. J., and Davis, M. E. (1999) New class of polymers for the delivery of macromolecular therapeutics. Bioconjugate Chem. 10, 1068-1074.
14. Hwang, S. J., Bellocq, N. C., and Davis, M. E. (2001) Effects of structure of β-cyclodextrin-containing polymers on gene delivery. Bioconjugate Chem. 12, 280-290.
15. Reineke, T. M., and Davis, M. E. (2003) Structural effects of carbohydrate-containing polycations on gene delivery. 1. Carbohydrate size and its distance from charge centers. Bioconjugate Chem. 14, 247-254.
16. Reineke, T. M., and Davis, M. E. (2003) Structural effects of carbohydrate-containing polycations on gene delivery. 2. Charge center type. Bioconjugate Chem. 14, 255-261.
17. Teranishi, K. (2000) Practicable regiospecific bifunctionalization on the secondary face of α and β-cyclodextrins. Chem. Commun. 14, 1255-1256.
18. B-disulfonated γ-cyclodextrin. Tetrahedron Lett. 41, 933-936.
19. Szejtli, J., Ed. (1988) Cyclodextrin Technology, Kluwer Academic Publishers, Dordrecht.
20. Pun, S. H., and Davis, M. E. (2002) Development of a nonviral gene delivery vehicle for systemic application. Bioconjugate Chem. 13, 630-639.