Delivery of messenger RNA using poly(ethylene imine)-poly(ethylene glycol)-copolymer blends for polyplex formation: Biophysical characterization and in vitro transfection properties

Journal of Controlled Release

Volumn 148, Issue 3, 2010, Pages 334-343

  Debus, Heiko ^a   Baumhof, Patrick ^b   Probst, Jochen ^b   Kissel, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b CureVac GmbH   (Germany)

Author keywords

Gene delivery; mRNA; Poly(ethylene imine); Polyplex; Transfection

Indexed keywords

GENE DELIVERY; MRNA; POLY(ETHYLENE IMINE); POLYPLEXES; TRANSFECTION;

COPOLYMERIZATION; COPOLYMERS; ETHYLENE; ETHYLENE GLYCOL; GENE THERAPY; GENE TRANSFER; NITROGEN COMPOUNDS; NUCLEIC ACIDS; OLIGONUCLEOTIDES; ORGANIC POLYMERS; POLYETHYLENE OXIDES; RNA;

POLYETHYLENE GLYCOLS;

COPOLYMER; LUCIFERASE; MACROGOL; MESSENGER RNA; NITROGEN; PHOSPHATE; POLYETHYLENEIMINE;

ANIMAL CELL; ARTICLE; COLLOID; COMPLEX FORMATION; CYTOTOXICITY; GENE DELIVERY SYSTEM; HYDRODYNAMICS BASED TRANSFECTION; LIGHT SCATTERING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA STABILITY; ZETA POTENTIAL;

ANIMALS; CELL LINE; CELL SURVIVAL; FIBROBLASTS; IMINES; MICE; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYETHYLENES; RNA, MESSENGER; TRANSFECTION;

EID: 78649761971     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.09.007     Document Type: Article

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