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Volumn 126, Issue 24, 2004, Pages 7422-7423

New poly(D-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; NANOPARTICLE; NUCLEIC ACID; POLY(DEXTRO GLUCARAMIDOAMINE); UNCLASSIFIED DRUG;

EID: 2942635107     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja049831l     Document Type: Article
Times cited : (128)

References (33)
  • 25
    • 2942666493 scopus 로고    scopus 로고
    • note
    • n respectively: 1, 3.0 kDa, 2.0; 2, 3.4 kDa, 1.4; 3, 3.9 kDa, 1.4; 4, 4.9 kDa, 1.6.
  • 26
    • 2942638321 scopus 로고    scopus 로고
    • note
    • α) indicate randomly coiled linear polymers.
  • 28
    • 2942670886 scopus 로고    scopus 로고
    • note
    • The amide nitrogens are not counted in this ratio since they will not display a positive charge within the physiological pH range (7.4-5.0).
  • 29
    • 2942673081 scopus 로고    scopus 로고
    • note
    • Polyplex sizes were determined with a Zetapals dynamic light scattering instrument (Brookhaven) at λ = 662 nm. Polyplexes were formed by combining each polymer (1-4) at an N/P ratio of 30 with 3μg of pDNA in 300 μL of DNAse free water. After 1 h, each solution was diluted with DNase free water to 0.7 mL. The results are reported as an average of 10 measurements: 256 nm (1), 441 nm (2), 140 nm (3), and 175 nm (4). TEM experimental details are given in the Supporting Information.
  • 30
    • 2942666494 scopus 로고    scopus 로고
    • note
    • 2. Media was replaced after 4 and 24 h following initial transfection (see Supporting Information).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.