-
1
-
-
12744279513
-
Low-pH-sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery
-
Li W., Huang Z., MacKay J.A., Grube S., and Szoka Jr. F.C. Low-pH-sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery. J. Gene Med. 7 1 (2005) 67-79
-
(2005)
J. Gene Med.
, vol.7
, Issue.1
, pp. 67-79
-
-
Li, W.1
Huang, Z.2
MacKay, J.A.3
Grube, S.4
Szoka Jr., F.C.5
-
2
-
-
57349184166
-
Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery
-
Ko Y.T., Kale A., Hartner W.C., Papahadjopoulos-Sternberg B., and Torchilin V.P. Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery. J. Control. Release 133 2 (2009) 132-138
-
(2009)
J. Control. Release
, vol.133
, Issue.2
, pp. 132-138
-
-
Ko, Y.T.1
Kale, A.2
Hartner, W.C.3
Papahadjopoulos-Sternberg, B.4
Torchilin, V.P.5
-
3
-
-
34249077607
-
Cell and tissue targeting of nucleic acids for cancer gene therapy
-
Russ V., and Wagner E. Cell and tissue targeting of nucleic acids for cancer gene therapy. Pharm. Res. 24 6 (2007) 1047-1057
-
(2007)
Pharm. Res.
, vol.24
, Issue.6
, pp. 1047-1057
-
-
Russ, V.1
Wagner, E.2
-
4
-
-
33847099637
-
Lipid-based nanoparticles for nucleic acid delivery
-
Li W., and Szoka Jr. F.C. Lipid-based nanoparticles for nucleic acid delivery. Pharm. Res. 24 3 (2007) 438-449
-
(2007)
Pharm. Res.
, vol.24
, Issue.3
, pp. 438-449
-
-
Li, W.1
Szoka Jr., F.C.2
-
5
-
-
56949083613
-
Peptide-modified vectors for nucleic acid delivery to neurons
-
Kwon E.J., Bergen J.M., Park I.K., and Pun S.H. Peptide-modified vectors for nucleic acid delivery to neurons. J. Control. Release 132 3 (2008) 230-235
-
(2008)
J. Control. Release
, vol.132
, Issue.3
, pp. 230-235
-
-
Kwon, E.J.1
Bergen, J.M.2
Park, I.K.3
Pun, S.H.4
-
6
-
-
42049109678
-
Conventional and gene therapy strategies for the treatment of brain tumors
-
Benitez J.A., Dominguez-Monzon G., and Segovia J. Conventional and gene therapy strategies for the treatment of brain tumors. Curr. Med. Chem. 15 8 (2008) 729-742
-
(2008)
Curr. Med. Chem.
, vol.15
, Issue.8
, pp. 729-742
-
-
Benitez, J.A.1
Dominguez-Monzon, G.2
Segovia, J.3
-
7
-
-
49049118656
-
An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives
-
Sasaki K., Kogure K., Chaki S., Nakamura Y., Moriguchi R., Hamada H., Danev R., Nagayama K., Futaki S., and Harashima H. An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives. Anal. Bioanal. Chem. 391 8 (2008) 2717-2727
-
(2008)
Anal. Bioanal. Chem.
, vol.391
, Issue.8
, pp. 2717-2727
-
-
Sasaki, K.1
Kogure, K.2
Chaki, S.3
Nakamura, Y.4
Moriguchi, R.5
Hamada, H.6
Danev, R.7
Nagayama, K.8
Futaki, S.9
Harashima, H.10
-
8
-
-
33847234266
-
Evaluation of an LC8-binding peptide for the attachment of artificial cargo to dynein
-
Bergen J.M., and Pun S.H. Evaluation of an LC8-binding peptide for the attachment of artificial cargo to dynein. Mol. Pharm. 4 1 (2007) 119-128
-
(2007)
Mol. Pharm.
, vol.4
, Issue.1
, pp. 119-128
-
-
Bergen, J.M.1
Pun, S.H.2
-
9
-
-
21744434206
-
Molecular motors as drug delivery vehicles
-
Cohen R.N., Rashkin M.J., Wen X., and Szoka J.F.C. Molecular motors as drug delivery vehicles. Drug Discov. Today: Technol. 2 1 (2005) 111-118
-
(2005)
Drug Discov. Today: Technol.
, vol.2
, Issue.1
, pp. 111-118
-
-
Cohen, R.N.1
Rashkin, M.J.2
Wen, X.3
Szoka, J.F.C.4
-
10
-
-
33644878890
-
The nuclear pore complex: the gateway to successful nonviral gene delivery
-
van der Aa M.A., Mastrobattista E., Oosting R.S., Hennink W.E., Koning G.A., and Crommelin D.J. The nuclear pore complex: the gateway to successful nonviral gene delivery. Pharm. Res. 23 3 (2006) 447-459
-
(2006)
Pharm. Res.
, vol.23
, Issue.3
, pp. 447-459
-
-
van der Aa, M.A.1
Mastrobattista, E.2
Oosting, R.S.3
Hennink, W.E.4
Koning, G.A.5
Crommelin, D.J.6
-
11
-
-
14044250982
-
Formation and intracellular trafficking of lipoplexes and polyplexes
-
Elouahabi A., and Ruysschaert J.M. Formation and intracellular trafficking of lipoplexes and polyplexes. Molec. Ther. 11 3 (2005) 336-347
-
(2005)
Molec. Ther.
, vol.11
, Issue.3
, pp. 336-347
-
-
Elouahabi, A.1
Ruysschaert, J.M.2
-
12
-
-
38649099106
-
Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET
-
Chen H.H., Ho Y.P., Jiang X., Mao H.Q., Wang T.H., and Leong K.W. Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET. Molec. Ther. 16 2 (2008) 324-332
-
(2008)
Molec. Ther.
, vol.16
, Issue.2
, pp. 324-332
-
-
Chen, H.H.1
Ho, Y.P.2
Jiang, X.3
Mao, H.Q.4
Wang, T.H.5
Leong, K.W.6
-
13
-
-
0028167731
-
The preparation of subcellular organelles from mouse-liver in self-generated gradients of iodixanol
-
Graham J., Ford T., and Rickwood D. The preparation of subcellular organelles from mouse-liver in self-generated gradients of iodixanol. Anal. Biochem. 220 2 (1994) 367-373
-
(1994)
Anal. Biochem.
, vol.220
, Issue.2
, pp. 367-373
-
-
Graham, J.1
Ford, T.2
Rickwood, D.3
-
14
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method
-
Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(T)(-Delta Delta C) method. Methods 25 4 (2001) 402-408
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
15
-
-
0036110686
-
Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes
-
Tachibana R., Harashima H., Ide N., Ukitsu S., Ohta Y., Suzuki N., Kikuchi H., Shinohara Y., and Kiwada H. Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes. Pharm. Res. 19 4 (2002) 377-381
-
(2002)
Pharm. Res.
, vol.19
, Issue.4
, pp. 377-381
-
-
Tachibana, R.1
Harashima, H.2
Ide, N.3
Ukitsu, S.4
Ohta, Y.5
Suzuki, N.6
Kikuchi, H.7
Shinohara, Y.8
Kiwada, H.9
-
16
-
-
0035287881
-
Ca2+-sensitive cytosolic nucleases prevent efficient delivery to the nucleus of injected plasmids
-
Pollard H., Toumaniantz G., Amos J.L., Avet-Loiseau H., Guihard G., Behr J.P., and Escande D. Ca2+-sensitive cytosolic nucleases prevent efficient delivery to the nucleus of injected plasmids. J. Gene Med. 3 2 (2001) 153-164
-
(2001)
J. Gene Med.
, vol.3
, Issue.2
, pp. 153-164
-
-
Pollard, H.1
Toumaniantz, G.2
Amos, J.L.3
Avet-Loiseau, H.4
Guihard, G.5
Behr, J.P.6
Escande, D.7
-
17
-
-
0032812716
-
Intracellular compartmentalization of DNA fragments in cultured airway epithelial cells mediated by cationic lipids
-
Holmes A.R., Dohrman A.F., Ellison A.R., Goncz K.K., and Gruenert D.C. Intracellular compartmentalization of DNA fragments in cultured airway epithelial cells mediated by cationic lipids. Pharm. Res. 16 7 (1999) 1020-1025
-
(1999)
Pharm. Res.
, vol.16
, Issue.7
, pp. 1020-1025
-
-
Holmes, A.R.1
Dohrman, A.F.2
Ellison, A.R.3
Goncz, K.K.4
Gruenert, D.C.5
-
18
-
-
0034167974
-
Nuclear-associated plasmid, but not cell-associated plasmid, is correlated with transgene expression in cultured mammalian cells
-
James M.B., and Giorgio T.D. Nuclear-associated plasmid, but not cell-associated plasmid, is correlated with transgene expression in cultured mammalian cells. Molec. Ther. 1 4 (2000) 339-346
-
(2000)
Molec. Ther.
, vol.1
, Issue.4
, pp. 339-346
-
-
James, M.B.1
Giorgio, T.D.2
-
19
-
-
0347651889
-
An assessment of relative transcriptional availability from nonviral vectors
-
Tachibana R., Ide N., Shinohara Y., Harashima H., Hunt C.A., and Kiwada H. An assessment of relative transcriptional availability from nonviral vectors. Int. J. Pharm. 270 1-2 (2004) 315-321
-
(2004)
Int. J. Pharm.
, vol.270
, Issue.1-2
, pp. 315-321
-
-
Tachibana, R.1
Ide, N.2
Shinohara, Y.3
Harashima, H.4
Hunt, C.A.5
Kiwada, H.6
-
20
-
-
31544438302
-
Non-linear pharmacodynamics in a non-viral gene delivery system: positive non-linear relationship between dose and transfection efficiency
-
Moriguchi R., Kogure K., Iwasa A., Akita H., and Harashima H. Non-linear pharmacodynamics in a non-viral gene delivery system: positive non-linear relationship between dose and transfection efficiency. J. Control. Release 110 3 (2006) 605-609
-
(2006)
J. Control. Release
, vol.110
, Issue.3
, pp. 605-609
-
-
Moriguchi, R.1
Kogure, K.2
Iwasa, A.3
Akita, H.4
Harashima, H.5
-
21
-
-
34247545030
-
Contamination of nuclear fractions with plasma membrane lipid rafts
-
Say Y.H., and Hooper N.M. Contamination of nuclear fractions with plasma membrane lipid rafts. Proteomics 7 7 (2007) 1059-1064
-
(2007)
Proteomics
, vol.7
, Issue.7
, pp. 1059-1064
-
-
Say, Y.H.1
Hooper, N.M.2
-
22
-
-
33646342766
-
Quantitative real-time polymerase chain reaction for determination of plasmid copy number in bacteria
-
Lee C.L., Ow D.S., and Oh S.K. Quantitative real-time polymerase chain reaction for determination of plasmid copy number in bacteria. J. Microbiol. Methods 65 2 (2006) 258-267
-
(2006)
J. Microbiol. Methods
, vol.65
, Issue.2
, pp. 258-267
-
-
Lee, C.L.1
Ow, D.S.2
Oh, S.K.3
-
23
-
-
31044436017
-
Determination of cytochrome P450 2D6 (CYP2D6) gene copy number by real-time quantitative PCR
-
Bodin L., Beaune P.H., and Loriot M.A. Determination of cytochrome P450 2D6 (CYP2D6) gene copy number by real-time quantitative PCR. J. Biomed. Biotechnol. 2005 3 (2005) 248-253
-
(2005)
J. Biomed. Biotechnol.
, vol.2005
, Issue.3
, pp. 248-253
-
-
Bodin, L.1
Beaune, P.H.2
Loriot, M.A.3
-
24
-
-
34247217272
-
Real-time quantitative PCR as an alternative to Southern blot or fluorescence in situ hybridization for detection of gene copy number changes
-
Hoebeeck J., Speleman F., and Vandesompele J. Real-time quantitative PCR as an alternative to Southern blot or fluorescence in situ hybridization for detection of gene copy number changes. Methods Mol. Biol. 353 (2007) 205-226
-
(2007)
Methods Mol. Biol.
, vol.353
, pp. 205-226
-
-
Hoebeeck, J.1
Speleman, F.2
Vandesompele, J.3
-
25
-
-
34247112229
-
Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex
-
Hama S., Akita H., Iida S., Mizuguchi H., and Harashima H. Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex. Nucleic Acids Res. 35 5 (2007) 1533-1543
-
(2007)
Nucleic Acids Res.
, vol.35
, Issue.5
, pp. 1533-1543
-
-
Hama, S.1
Akita, H.2
Iida, S.3
Mizuguchi, H.4
Harashima, H.5
-
26
-
-
33645528583
-
Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems
-
Hama S., Akita H., Ito R., Mizuguchi H., Hayakawa T., and Harashima H. Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems. Molec. Ther. 13 4 (2006) 786-794
-
(2006)
Molec. Ther.
, vol.13
, Issue.4
, pp. 786-794
-
-
Hama, S.1
Akita, H.2
Ito, R.3
Mizuguchi, H.4
Hayakawa, T.5
Harashima, H.6
-
27
-
-
0034607160
-
Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery
-
Schaffer D.V., Fidelman N.A., Dan N., and Lauffenburger D.A. Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery. Biotechnol. Bioeng. 67 5 (2000) 598-606
-
(2000)
Biotechnol. Bioeng.
, vol.67
, Issue.5
, pp. 598-606
-
-
Schaffer, D.V.1
Fidelman, N.A.2
Dan, N.3
Lauffenburger, D.A.4
-
28
-
-
0033609001
-
Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery
-
Godbey W.T., Wu K.K., and Mikos A.G. Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery. Proc. Natl. Acad. Sci. U. S. A. 96 9 (1999) 5177-5181
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, Issue.9
, pp. 5177-5181
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
29
-
-
33846390694
-
Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA
-
Koynova R., Tarahovsky Y.S., Wang L., and MacDonald R.C. Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim. Biophys. Acta 1768 2 (2007) 375-386
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, Issue.2
, pp. 375-386
-
-
Koynova, R.1
Tarahovsky, Y.S.2
Wang, L.3
MacDonald, R.C.4
-
30
-
-
0029949266
-
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
-
Xu Y., and Szoka Jr. F.C. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35 18 (1996) 5616-5623
-
(1996)
Biochemistry
, vol.35
, Issue.18
, pp. 5616-5623
-
-
Xu, Y.1
Szoka Jr., F.C.2
-
31
-
-
19744372388
-
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
-
Akinc A., Thomas M., Klibanov A.M., and Langer R. Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J. Gene Med. 7 5 (2005) 657-663
-
(2005)
J. Gene Med.
, vol.7
, Issue.5
, pp. 657-663
-
-
Akinc, A.1
Thomas, M.2
Klibanov, A.M.3
Langer, R.4
-
32
-
-
0242414440
-
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
-
Sonawane N.D., Szoka Jr. F.C., and Verkman A.S. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J. Biol. Chem. 278 45 (2003) 44826-44831
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.45
, pp. 44826-44831
-
-
Sonawane, N.D.1
Szoka Jr., F.C.2
Verkman, A.S.3
-
33
-
-
38649138015
-
Cell surface nucleolin serves as receptor for DNA nanoparticles composed of pegylated polylysine and DNA
-
Chen X., Kube D.M., Cooper M.J., and Davis P.B. Cell surface nucleolin serves as receptor for DNA nanoparticles composed of pegylated polylysine and DNA. Molec. Ther. 16 2 (2008) 333-342
-
(2008)
Molec. Ther.
, vol.16
, Issue.2
, pp. 333-342
-
-
Chen, X.1
Kube, D.M.2
Cooper, M.J.3
Davis, P.B.4
-
34
-
-
0036429187
-
Visualization of intracellular trafficking of exogenous DNA delivered by cationic liposomes
-
Kamiya H., Fujimura Y., Matsuoka I., and Harashima H. Visualization of intracellular trafficking of exogenous DNA delivered by cationic liposomes. Biochem. Biophys. Res. Commun. 298 4 (2002) 591-597
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.298
, Issue.4
, pp. 591-597
-
-
Kamiya, H.1
Fujimura, Y.2
Matsuoka, I.3
Harashima, H.4
-
35
-
-
0030761195
-
Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression
-
Tseng W.C., Haselton F.R., and Giorgio T.D. Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression. J. Biol. Chem. 272 41 (1997) 25641-25647
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.41
, pp. 25641-25647
-
-
Tseng, W.C.1
Haselton, F.R.2
Giorgio, T.D.3
-
36
-
-
33846049519
-
Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells
-
Carpentier E., Paris S., Kamen A.A., and Durocher Y. Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells. J. Biotechnol. 128 2 (2007) 268-280
-
(2007)
J. Biotechnol.
, vol.128
, Issue.2
, pp. 268-280
-
-
Carpentier, E.1
Paris, S.2
Kamen, A.A.3
Durocher, Y.4
-
37
-
-
0034059514
-
Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus
-
Brunner S., Sauer T., Carotta S., Cotten M., Saltik M., and Wagner E. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus. Gene Ther. 7 5 (2000) 401-407
-
(2000)
Gene Ther.
, vol.7
, Issue.5
, pp. 401-407
-
-
Brunner, S.1
Sauer, T.2
Carotta, S.3
Cotten, M.4
Saltik, M.5
Wagner, E.6
-
38
-
-
33746238256
-
Which mechanism for nuclear import of plasmid DNA complexed with polyethylenimine derivatives?
-
Grosse S., Thevenot G., Monsigny M., and Fajac I. Which mechanism for nuclear import of plasmid DNA complexed with polyethylenimine derivatives?. J. Gene Med. 8 7 (2006) 845-851
-
(2006)
J. Gene Med.
, vol.8
, Issue.7
, pp. 845-851
-
-
Grosse, S.1
Thevenot, G.2
Monsigny, M.3
Fajac, I.4
-
39
-
-
34347267310
-
Polyplex-mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans
-
Mannisto M., Reinisalo M., Ruponen M., Honkakoski P., Tammi M., and Urtti A. Polyplex-mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans. J. Gene Med. 9 6 (2007) 479-487
-
(2007)
J. Gene Med.
, vol.9
, Issue.6
, pp. 479-487
-
-
Mannisto, M.1
Reinisalo, M.2
Ruponen, M.3
Honkakoski, P.4
Tammi, M.5
Urtti, A.6
-
40
-
-
0033553126
-
Mitosis enhances transgene expression of plasmid delivered by cationic liposomes
-
Tseng W.C., Haselton F.R., and Giorgio T.D. Mitosis enhances transgene expression of plasmid delivered by cationic liposomes. Biochim. Biophys. Acta 1445 1 (1999) 53-64
-
(1999)
Biochim. Biophys. Acta
, vol.1445
, Issue.1
, pp. 53-64
-
-
Tseng, W.C.1
Haselton, F.R.2
Giorgio, T.D.3
-
41
-
-
0019191911
-
High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
-
Capecchi M.R. High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22 2 Pt 2 (1980) 479-488
-
(1980)
Cell
, vol.22
, Issue.2 PART 2
, pp. 479-488
-
-
Capecchi, M.R.1
-
42
-
-
34447633952
-
Transient activation of transgene expression by hydrodynamics-based injection may cause rapid decrease in plasmid DNA expression
-
Ochiai H., Fujimuro M., Yokosawa H., Harashima H., and Kamiya H. Transient activation of transgene expression by hydrodynamics-based injection may cause rapid decrease in plasmid DNA expression. Gene Ther. 14 15 (2007) 1152-1159
-
(2007)
Gene Ther.
, vol.14
, Issue.15
, pp. 1152-1159
-
-
Ochiai, H.1
Fujimuro, M.2
Yokosawa, H.3
Harashima, H.4
Kamiya, H.5
-
43
-
-
56649121906
-
In vivo gene delivery in the mouse lung with lactosylated polyethylenimine, questioning the relevance of in vitro experiments
-
Grosse S., Thevenot G., Aron Y., Duverger E., Abdelkarim M., Roche A.C., Monsigny M., and Fajac I. In vivo gene delivery in the mouse lung with lactosylated polyethylenimine, questioning the relevance of in vitro experiments. J. Control. Release 132 2 (2008) 105-112
-
(2008)
J. Control. Release
, vol.132
, Issue.2
, pp. 105-112
-
-
Grosse, S.1
Thevenot, G.2
Aron, Y.3
Duverger, E.4
Abdelkarim, M.5
Roche, A.C.6
Monsigny, M.7
Fajac, I.8
|