Nuclear co-localization and functional interaction of COX-2 and HIF-1α characterize bone metastasis of human breast carcinoma

Breast Cancer Research and Treatment

Volumn 129, Issue 2, 2011, Pages 433-450

  Maroni, Paola ^a   Matteucci, Emanuela ^b   Luzzati, Alessandro ^a   Perrucchini, Giuseppe ^a   Bendinelli, Paola ^b   Desiderio, Maria Alfonsina ^b  

^a IRCCS ISTITUTO ORTOPEDICO GALEAZZI   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Bone metastasis; Bone microenvironment; Breast cancer; COX 2; HIF 1

Indexed keywords

CYCLOOXYGENASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; AUTOREGULATION; BONE MARROW; BONE METASTASIS; BREAST CARCINOMA; CANCER CELL CULTURE; CELL ACTIVATION; CELL NUCLEUS; CONTROLLED STUDY; ENGRAFTMENT; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; METASTASIS POTENTIAL; NUCLEAR IMPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; BONE NEOPLASMS; BREAST NEOPLASMS; CARCINOMA; CELL HYPOXIA; CELL LINE, TUMOR; CELL NUCLEUS; CYCLOOXYGENASE 2; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE GROWTH FACTOR; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; MICE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MICROENVIRONMENT;

EID: 80051792139     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1240-1     Document Type: Article

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