Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: Potential regulation by ligand-dependent degradation and HIF-1α

Biochemical and Biophysical Research Communications

Volumn 346, Issue 1, 2006, Pages 252-258

  Shim, Hyunsuk ^a   Lau, Stephen K ^a   Devi, Sarojini ^a   Yoon, Younghyoun ^a   Cho, Heidi T ^a   Liang, Zhongxing ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; CXCR4; HIF 1 ; Lymph node metastasis; SDF 1

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; HYPOXIA INDUCIBLE FACTOR 1ALPHA; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INVASION; CELL MEMBRANE; CONTROLLED STUDY; DATA ANALYSIS; HUMAN; HUMAN CELL; HYPOTHESIS; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LYMPH NODE METASTASIS; LYSOSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BREAST NEOPLASMS; CELL LINE, TUMOR; CHEMOKINES, CXC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LYMPHATIC METASTASIS; RECEPTORS, CXCR4;

EID: 33744994778     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.05.110     Document Type: Article

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