Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: Signal amplification via multivalency

Bioconjugate Chemistry

Volumn 22, Issue 8, 2011, Pages 1650-1662

  Singh, Ajay N ^a   Liu, Wei ^a,c   Hao, Guiyang ^a   Kumar, Amit ^a   Gupta, Anjali ^a   Öz, Orhan K ^a   Hsieh, Jer Tsong ^a   Sun, Xiankai ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLIFICATION; BINDING ENERGY; GALLIUM; GALLIUM COMPOUNDS; INFRARED DEVICES; MOLECULAR IMAGING; PEPTIDES; POSITRON EMISSION TOMOGRAPHY; PROBES; SCAFFOLDS; TUMORS;

BI-FUNCTIONAL; IMAGING PROBE; IN-VIVO; INTEGRINS; MULTIVALENCY; MULTIVALENT EFFECT; POST INJECTION; PROBE DESIGN; SIGNAL AMPLIFICATIONS; TRIAZACYCLONONANE;

CHELATION;

1,4,7 TRIAZACYCLONONANE 1,4,7 TRIACETIC ACID GA 68; GALLIUM 68; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; DRUG UPTAKE; GLIOBLASTOMA; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VIVO STUDY; KIDNEY; LIVER; MALE; MOLECULAR IMAGING; MOUSE; MUSCLE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROSTATE CANCER; ROOM TEMPERATURE; TUMOR XENOGRAFT;

MUS;

EID: 80051762411     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200227d     Document Type: Article

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