Imparting multivalency to a bifunctional chelator: A scaffold design for targeted PET imaging probes

Angewandte Chemie - International Edition

Volumn 48, Issue 40, 2009, Pages 7346-7349

  Liu, Wei ^a   Hao, Guiyang ^a   Long, Michael A ^a   Anthony, Tiffani ^a   Hsieh, Jer Tsong ^b   Sun, Xiankai ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Chelates; Imaging agents; Multivalent effect; Radiochemistry

Indexed keywords

BIFUNCTIONAL; CHELATES; IMAGING AGENTS; IN-VIVO; MULTIVALENCY; MULTIVALENT EFFECT; NEUTRAL COMPLEXES; PET IMAGING; RADIOCHEMISTRY; TARGETING MOLECULES;

CHELATION; FUNCTIONAL GROUPS; PROBES;

SCAFFOLDS;

ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; CHELATING AGENT; CYCLOPEPTIDE; OLIGOPEPTIDE; VITRONECTIN RECEPTOR;

ANIMAL; ARTICLE; CHEMISTRY; DRUG DESIGN; HUMAN; METABOLISM; MOUSE; NEOPLASM; POSITRON EMISSION TOMOGRAPHY; SYNTHESIS; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CHELATING AGENTS; DRUG DESIGN; HUMANS; INTEGRIN ALPHAVBETA3; MICE; NEOPLASMS; OLIGOPEPTIDES; PEPTIDES, CYCLIC; POSITRON-EMISSION TOMOGRAPHY; TRANSPLANTATION, HETEROLOGOUS;

EID: 70349922812     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200903556     Document Type: Article

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