Macrocyclic chelator assembled RGD multimers for tumor targeting

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 11, 2011, Pages 3423-3426

  Zhang, Xiaofen ^a,b   Liu, Hongguang ^a   Miao, Zheng ^a   Kimura, Richard ^a   Fan, Feiyue ^b   Cheng, Zhen ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

Integrin; Molecular imaging; Multivalency; PET; RGD peptide

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; ANTINEOPLASTIC METAL COMPLEX; ARGINYLGLYCYLASPARTIC ACID; CHELATING AGENT; COPPER 64; COPPER 64 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID ARGINYLGLYCYLASPARTIC ACID PEPTIDE; EUROPIUM; GADOLINIUM; GALLIUM 68; HOLMIUM; HOLMIUM 166; INDIUM 111; LUTETIUM 177; TERBIUM; UNCLASSIFIED DRUG; YTTERBIUM; YTTRIUM 86; YTTRIUM 90;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG TARGETING; DRUG UPTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IC 50; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR IMAGING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; ONE POT SYNTHESIS; POSITRON EMISSION TOMOGRAPHY;

ANIMALS; CHELATING AGENTS; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEMS; HETEROCYCLIC COMPOUNDS, 1-RING; MACROCYCLIC COMPOUNDS; MICE; MOLECULAR STRUCTURE; NEOPLASMS; OLIGOPEPTIDES;

EID: 79956092631     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.03.110     Document Type: Article

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