메뉴 건너뛰기




Volumn 6, Issue 8, 2011, Pages

The mitochondrial genome is a "genetic sanctuary" during the oncogenic process

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

EID: 80051752056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023327     Document Type: Article
Times cited : (23)

References (44)
  • 1
    • 33745274726 scopus 로고    scopus 로고
    • Mitochondria: Dynamic organelles in disease, aging, and development
    • Chan DC, (2006) Mitochondria: Dynamic organelles in disease, aging, and development. Cell 125: 1241-1252.
    • (2006) Cell , vol.125 , pp. 1241-1252
    • Chan, D.C.1
  • 2
    • 33746016268 scopus 로고    scopus 로고
    • Mitochondria: More than just a powerhouse
    • McBride HM, Neuspiel M, Wasiak S, (2006) Mitochondria: More than just a powerhouse. Curr Biol 16: R551-R560.
    • (2006) Curr Biol , vol.16
    • McBride, H.M.1    Neuspiel, M.2    Wasiak, S.3
  • 3
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO, (2000) The biochemistry of apoptosis. Nature 407: 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 4
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • Lowe SW, Cepero E, Evan G, (2004) Intrinsic tumour suppression. Nature 432: 307-315.
    • (2004) Nature , vol.432 , pp. 307-315
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 6
    • 37449034854 scopus 로고    scopus 로고
    • Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
    • DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, et al. (2007) Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci U S A 104: 19345-19350.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19345-19350
    • DeBerardinis, R.J.1    Mancuso, A.2    Daikhin, E.3    Nissim, I.4    Yudkoff, M.5
  • 7
    • 77953500851 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases and cancer
    • de Moura MB, dos Santos LS, Van Houten B, (2010) Mitochondrial dysfunction in neurodegenerative diseases and cancer. Environ Mol Mutagen 51: 391-405.
    • (2010) Environ Mol Mutagen , vol.51 , pp. 391-405
    • de Moura, M.B.1    dos Santos, L.S.2    Van Houten, B.3
  • 8
    • 1442303118 scopus 로고    scopus 로고
    • mtDNA mutations in tumors of the central nervous system reflect the neutral evolution of mtDNA in populations
    • Vega A, Salas A, Gamborino E, Sobrido MJ, Macaulay V, et al. (2004) mtDNA mutations in tumors of the central nervous system reflect the neutral evolution of mtDNA in populations. Oncogene 23: 1314-1320.
    • (2004) Oncogene , vol.23 , pp. 1314-1320
    • Vega, A.1    Salas, A.2    Gamborino, E.3    Sobrido, M.J.4    Macaulay, V.5
  • 9
    • 38849175587 scopus 로고    scopus 로고
    • Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer
    • Dasgupta S, Hoque MO, Upadhyay S, Sidransky D, (2008) Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer. Cancer Res 68: 700-706.
    • (2008) Cancer Res , vol.68 , pp. 700-706
    • Dasgupta, S.1    Hoque, M.O.2    Upadhyay, S.3    Sidransky, D.4
  • 10
    • 43549098260 scopus 로고    scopus 로고
    • The oncogene c-myc coordinates regulation of metabolic networks to enable rapid cell cycle entry
    • Morrish F, Neretti N, Sedivy JM, Hockenbery DM, (2008) The oncogene c-myc coordinates regulation of metabolic networks to enable rapid cell cycle entry. Cell Cycle 7: 1054-1066.
    • (2008) Cell Cycle , vol.7 , pp. 1054-1066
    • Morrish, F.1    Neretti, N.2    Sedivy, J.M.3    Hockenbery, D.M.4
  • 11
    • 57749088701 scopus 로고    scopus 로고
    • Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
    • Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, et al. (2008) Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc Natl Acad Sci U S A 105: 18782-18787.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 18782-18787
    • Wise, D.R.1    DeBerardinis, R.J.2    Mancuso, A.3    Sayed, N.4    Zhang, X.Y.5
  • 12
    • 77957907225 scopus 로고    scopus 로고
    • Phospholipase D-mTOR requirement for the warburg effect in human cancer cells
    • Toschi A, Lee E, Thompson S, Gadir N, Yellen P, et al. (2010) Phospholipase D-mTOR requirement for the warburg effect in human cancer cells. Cancer Lett 299: 72-79.
    • (2010) Cancer Lett , vol.299 , pp. 72-79
    • Toschi, A.1    Lee, E.2    Thompson, S.3    Gadir, N.4    Yellen, P.5
  • 14
    • 43249112094 scopus 로고    scopus 로고
    • ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
    • Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, et al. (2008) ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science 320: 661-664.
    • (2008) Science , vol.320 , pp. 661-664
    • Ishikawa, K.1    Takenaga, K.2    Akimoto, M.3    Koshikawa, N.4    Yamaguchi, A.5
  • 15
    • 2642527955 scopus 로고    scopus 로고
    • Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation
    • Woo RA, Poon RY, (2004) Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation. Genes Dev 18: 1317-1330.
    • (2004) Genes Dev , vol.18 , pp. 1317-1330
    • Woo, R.A.1    Poon, R.Y.2
  • 16
    • 2442693092 scopus 로고    scopus 로고
    • The superoxide-generating oxidase Nox1 is functionally required for ras oncogene transformation
    • Mitsushita J, Lambeth JD, Kamata T, (2004) The superoxide-generating oxidase Nox1 is functionally required for ras oncogene transformation. Cancer Res 64: 3580-3585.
    • (2004) Cancer Res , vol.64 , pp. 3580-3585
    • Mitsushita, J.1    Lambeth, J.D.2    Kamata, T.3
  • 17
    • 33744465025 scopus 로고    scopus 로고
    • Mitochondria damage checkpoint, aging, and cancer
    • Singh KK, (2006) Mitochondria damage checkpoint, aging, and cancer. Ann N Y Acad Sci 1067: 182-190.
    • (2006) Ann N Y Acad Sci , vol.1067 , pp. 182-190
    • Singh, K.K.1
  • 18
    • 0033583242 scopus 로고    scopus 로고
    • Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
    • Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, et al. (1999) Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem 274: 7936-7940.
    • (1999) J Biol Chem , vol.274 , pp. 7936-7940
    • Lee, A.C.1    Fenster, B.E.2    Ito, H.3    Takeda, K.4    Bae, N.S.5
  • 19
    • 35348931672 scopus 로고    scopus 로고
    • H-ras mutation modulates the expression of major cell cycle regulatory proteins and disease prognosis in oral carcinoma
    • Sathyan KM, Nalinakumari KR, Kannan S, (2007) H-ras mutation modulates the expression of major cell cycle regulatory proteins and disease prognosis in oral carcinoma. Mod Pathol 20: 1141-1148.
    • (2007) Mod Pathol , vol.20 , pp. 1141-1148
    • Sathyan, K.M.1    Nalinakumari, K.R.2    Kannan, S.3
  • 20
    • 28444447123 scopus 로고    scopus 로고
    • A critical reassessment of the role of mitochondria in tumorigenesis
    • Salas A, Yao YG, Macaulay V, Vega A, Carracedo A, et al. (2005) A critical reassessment of the role of mitochondria in tumorigenesis. PLoS Med 2: e296.
    • (2005) PLoS Med , vol.2
    • Salas, A.1    Yao, Y.G.2    Macaulay, V.3    Vega, A.4    Carracedo, A.5
  • 21
    • 65649095622 scopus 로고    scopus 로고
    • Contamination and sample mix-up can best explain some patterns of mtDNA instabilities in buccal cells and oral squamous cell carcinoma
    • Bandelt H-J, Salas A, (2009) Contamination and sample mix-up can best explain some patterns of mtDNA instabilities in buccal cells and oral squamous cell carcinoma. BMC Cancer 9: 113.
    • (2009) BMC Cancer , vol.9 , pp. 113
    • Bandelt, H.-J.1    Salas, A.2
  • 23
    • 56649117372 scopus 로고    scopus 로고
    • Retinoblastoma loss modulates DNA damage response favoring tumor progression
    • Seoane M, Iglesias P, Gonzalez T, Dominguez F, Fraga M, et al. (2008) Retinoblastoma loss modulates DNA damage response favoring tumor progression. PLoS One 3: e3632.
    • (2008) PLoS One , vol.3
    • Seoane, M.1    Iglesias, P.2    Gonzalez, T.3    Dominguez, F.4    Fraga, M.5
  • 24
    • 0034656212 scopus 로고    scopus 로고
    • Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of rb in the external granular layer cells of the cerebellum
    • Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A, (2000) Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of rb in the external granular layer cells of the cerebellum. Genes Dev 14: 994-1004.
    • (2000) Genes Dev , vol.14 , pp. 994-1004
    • Marino, S.1    Vooijs, M.2    van Der Gulden, H.3    Jonkers, J.4    Berns, A.5
  • 25
    • 0030980641 scopus 로고    scopus 로고
    • Mitogenic signaling mediated by oxidants in ras-transformed fibroblasts
    • Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, et al. (1997) Mitogenic signaling mediated by oxidants in ras-transformed fibroblasts. Science 275: 1649-1652.
    • (1997) Science , vol.275 , pp. 1649-1652
    • Irani, K.1    Xia, Y.2    Zweier, J.L.3    Sollott, S.J.4    Der, C.J.5
  • 26
    • 0028338927 scopus 로고
    • The human ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle
    • Denko NC, Giaccia AJ, Stringer JR, Stambrook PJ, (1994) The human ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. Proc Natl Acad Sci U S A 91: 5124-5128.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5124-5128
    • Denko, N.C.1    Giaccia, A.J.2    Stringer, J.R.3    Stambrook, P.J.4
  • 27
    • 0028338927 scopus 로고
    • The human ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle
    • Denko NC, Giaccia AJ, Stringer JR, Stambrook PJ, (1994) The human ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. Proc Natl Acad Sci U S A 91: 5124-5128.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5124-5128
    • Denko, N.C.1    Giaccia, A.J.2    Stringer, J.R.3    Stambrook, P.J.4
  • 28
    • 0000220411 scopus 로고    scopus 로고
    • The retinoblastoma protein is linked to the activation of ras
    • Lee KY, Ladha MH, McMahon C, Ewen ME, (1999) The retinoblastoma protein is linked to the activation of ras. Mol Cell Biol 19: 7724-7732.
    • (1999) Mol Cell Biol , vol.19 , pp. 7724-7732
    • Lee, K.Y.1    Ladha, M.H.2    McMahon, C.3    Ewen, M.E.4
  • 29
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
    • Aruoma OI, Halliwell B, Hoey BM, Butler J, (1989) The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic Biol Med 6: 593-597.
    • (1989) Free Radic Biol Med , vol.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 30
    • 0024512008 scopus 로고
    • Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration
    • Burgunder JM, Varriale A, Lauterburg BH, (1989) Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration. Eur J Clin Pharmacol 36: 127-131.
    • (1989) Eur J Clin Pharmacol , vol.36 , pp. 127-131
    • Burgunder, J.M.1    Varriale, A.2    Lauterburg, B.H.3
  • 31
    • 33847694330 scopus 로고    scopus 로고
    • mtDNA phylogeny and evolution of laboratory mouse strains
    • Goios A, Pereira L, Bogue M, Macaulay V, Amorim A, (2007) mtDNA phylogeny and evolution of laboratory mouse strains. Genome Res 17: 293-298.
    • (2007) Genome Res , vol.17 , pp. 293-298
    • Goios, A.1    Pereira, L.2    Bogue, M.3    Macaulay, V.4    Amorim, A.5
  • 32
    • 34147095602 scopus 로고    scopus 로고
    • Phylogeographic investigations: The role of trees in forensic genetics
    • Salas A, Bandelt H-J, Macaulay V, Richards MB, (2007) Phylogeographic investigations: The role of trees in forensic genetics. Forensic Sci Int 168: 1-13.
    • (2007) Forensic Sci Int , vol.168 , pp. 1-13
    • Salas, A.1    Bandelt, H.-J.2    Macaulay, V.3    Richards, M.B.4
  • 33
    • 64049089255 scopus 로고    scopus 로고
    • Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
    • van Oven M, Kayser M, (2009) Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 30: E386-94.
    • (2009) Hum Mutat , vol.30
    • van Oven, M.1    Kayser, M.2
  • 34
    • 64549148932 scopus 로고    scopus 로고
    • New population and phylogenetic features of the internal variation within mitochondrial DNA macro-haplogroup R0
    • Alvarez-Iglesias V, Mosquera-Miguel A, Cerezo M, Quintans B, Zarrabeitia MT, et al. (2009) New population and phylogenetic features of the internal variation within mitochondrial DNA macro-haplogroup R0. PLoS One 4: e5112.
    • (2009) PLoS One , vol.4
    • Alvarez-Iglesias, V.1    Mosquera-Miguel, A.2    Cerezo, M.3    Quintans, B.4    Zarrabeitia, M.T.5
  • 35
    • 50949130722 scopus 로고    scopus 로고
    • Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast
    • Zuin A, Gabrielli N, Calvo IA, Garcia-Santamarina S, Hoe KL, et al. (2008) Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast. PLoS One 3: e2842.
    • (2008) PLoS One , vol.3
    • Zuin, A.1    Gabrielli, N.2    Calvo, I.A.3    Garcia-Santamarina, S.4    Hoe, K.L.5
  • 36
    • 0026658124 scopus 로고
    • Mitochondrial DNA damage by anticancer agents
    • Singh G, Sharkey SM, Moorehead R, (1992) Mitochondrial DNA damage by anticancer agents. Pharmacol Ther 54: 217-230.
    • (1992) Pharmacol Ther , vol.54 , pp. 217-230
    • Singh, G.1    Sharkey, S.M.2    Moorehead, R.3
  • 37
    • 41149105722 scopus 로고    scopus 로고
    • Mitochondria in cancer cells: What is so special about them?
    • Gogvadze V, Orrenius S, Zhivotovsky B, (2008) Mitochondria in cancer cells: What is so special about them? Trends Cell Biol 18 (4): 165-173.
    • (2008) Trends Cell Biol , vol.18 , Issue.4 , pp. 165-173
    • Gogvadze, V.1    Orrenius, S.2    Zhivotovsky, B.3
  • 38
    • 23944434487 scopus 로고    scopus 로고
    • A practical guide to mitochondrial DNA error prevention in clinical, forensic, and population genetics
    • Salas A, Carracedo Á, Macaulay V, Richards M, Bandelt H-J, (2005) A practical guide to mitochondrial DNA error prevention in clinical, forensic, and population genetics. Biochem Biophys Res Commun 335: 891-899.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 891-899
    • Salas, A.1    Carracedo, A.2    Macaulay, V.3    Richards, M.4    Bandelt, H.-J.5
  • 40
    • 0032868141 scopus 로고    scopus 로고
    • Reanalysis and revision of the cambridge reference sequence for human mitochondrial DNA
    • Andrews RM, Kubacka I, Chinnery PF, Lightowlers RN, Turnbull DM, et al. (1999) Reanalysis and revision of the cambridge reference sequence for human mitochondrial DNA. Nat Genet 23: 147.
    • (1999) Nat Genet , vol.23 , pp. 147
    • Andrews, R.M.1    Kubacka, I.2    Chinnery, P.F.3    Lightowlers, R.N.4    Turnbull, D.M.5
  • 41
    • 29744438489 scopus 로고    scopus 로고
    • The absence of mitochondrial DNA diversity among common laboratory inbred mouse strains
    • Dai JG, Min JX, Xiao YB, Lei X, Shen WH, et al. (2005) The absence of mitochondrial DNA diversity among common laboratory inbred mouse strains. J Exp Biol 208 (Pt 23): 4445-4450.
    • (2005) J Exp Biol , vol.208 , Issue.PART 23 , pp. 4445-4450
    • Dai, J.G.1    Min, J.X.2    Xiao, Y.B.3    Lei, X.4    Shen, W.H.5
  • 42
    • 0035205417 scopus 로고    scopus 로고
    • Do the four clades of the mtDNA haplogroup L2 evolve at different rates?
    • Torroni A, Rengo C, Guida V, Cruciani F, Sellitto D, et al. (2001) Do the four clades of the mtDNA haplogroup L2 evolve at different rates? Am J Hum Genet 69 (6): 1348-1356.
    • (2001) Am J Hum Genet , vol.69 , Issue.6 , pp. 1348-1356
    • Torroni, A.1    Rengo, C.2    Guida, V.3    Cruciani, F.4    Sellitto, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.