Physiologically based pharmacokinetic modeling of fetal and neonatal manganese exposure in humans: Describing manganese homeostasis during development

Toxicological Sciences

Volumn 122, Issue 2, 2011, Pages 297-316

  Yoon, Miyoung ^a   Schroeter, Jeffry D ^a   Nong, Andy ^a   Taylor, Michael D ^b   Dorman, David C ^c   Andersen, Melvin E ^a   Clewell, Harvey J ^a  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b AFTON CHEMICAL CORPORATION   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Environmental exposure to Mn; Fetus; Formula; Manganese; Neonate; Potentially susceptible subpopulation

Indexed keywords

DRINKING WATER; MANGANESE;

ADULT; ALLOMETRY; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL MILK; BRAIN; BREAST MILK; CONTROLLED STUDY; DEVELOPMENT; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; EXPOSURE; FETUS; HOMEOSTASIS; HUMAN; KINETICS; LACTATION; MALE; MILK; MODEL; NEUROTOXICITY; NEWBORN; NONHUMAN; PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL; PLACENTA; PREGNANCY; RAT; TISSUE DISTRIBUTION; UMBILICAL CORD BLOOD;

ADULT; ANIMALS; CHILD, PRESCHOOL; FEMALE; FETUS; HOMEOSTASIS; HUMANS; INFANT; INHALATION EXPOSURE; LACTATION; MALE; MANGANESE; MATERNAL EXPOSURE; MILK, HUMAN; MODELS, BIOLOGICAL; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; TISSUE DISTRIBUTION;

RATTUS; RODENTIA;

EID: 80051700457     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr141     Document Type: Article

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