Evaluating placental transfer and tissue concentrations of manganese in the pregnant rat and fetuses after inhalation exposures with a PBPK model

Toxicological Sciences

Volumn 112, Issue 1, 2009, Pages 44-58

  Yoon, Miyoung ^a   Nong, Andy ^a   Clewell, Harvey J ^a   Taylor, Michael D ^b   Dorman, David C ^a,c   Andersen, Melvin E ^a  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b AFTON CHEMICAL CORPORATION   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Gestation; Homeostasis during gestation; Inhalation exposure; Manganese; PBPK; Placental transfer

Indexed keywords

MANGANESE;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DIFFUSION; DISEASE MODEL; FEMALE; LACTATION; NEUROTOXICITY; NONHUMAN; PLACENTAL TRANSFER; PREGNANCY; RAT; SIMULATION; TISSUE DISTRIBUTION; TOXIC INHALATION; TOXICOKINETICS;

ANIMALS; FEMALE; FETUS; HOMEOSTASIS; INHALATION EXPOSURE; MANGANESE; MATERNAL-FETAL EXCHANGE; PLACENTA; PREGNANCY; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

RATTUS;

EID: 71049118066     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp198     Document Type: Article

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