Developmental changes in the expression of iron regulatory proteins and iron transport proteins in the perinatal rat brain

Journal of Neuroscience Research

Volumn 68, Issue 6, 2002, Pages 761-775

  Siddappa, Asha Jyothi M ^a   Rao, Raghavendra B ^a,b   Wobken, Jane D ^a   Leibold, Elizabeth A ^c   Connor, James R ^d   Georgieff, Michael K ^a,b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Brain; Divalent metal transporter 1; Iron; Regulation; Transferrin receptor

Indexed keywords

BRAIN PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; IRON; IRON REGULATORY FACTOR; IRON TRANSPORT PROTEIN; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN BLOOD VESSEL; CHOROID PLEXUS; CONTROLLED STUDY; NONHUMAN; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM;

ANIMALS; BRAIN; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; IMMUNOHISTOCHEMISTRY; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; IRON-BINDING PROTEINS; IRON-REGULATORY PROTEINS; IRON-SULFUR PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TRANSFERRIN; RNA-BINDING PROTEINS; TIME FACTORS;

EID: 0037097199     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10246     Document Type: Article

References (39)

1. Disorders of iron metabolism
2. Hippocampal development in the rat: Cytogenesis and morphogenesis examined with autoradiography and low-level X-irradiation
3. Iron metabolism: A comprehensive review
4. Brain iron: Location and function
5. Iron transport in the central nervous system
6. Distribution of divalent metal transporter 1 and metal transport protein 1 in normal and Belgrade rat
7. Iron acquisition and expression of iron regulatory proteins in the developing brain: Manipulation by ethanol exposure, iron deprivation and cellular dysfunction
8. Development of transferrin-positive oligodendrocytes in the rat central nervous system
9. Cellular management of iron in the brain
10. Relationship of iron to oligodendrocytes and myelination
11. Perinatal iron deficiency decreases cytochrome c oxidase activity in selected regions of neonatal rat brain
12. Iron regulatory proteins and the molecular control of mammalian iron metabolism
13. Iron regulatory proteins, iron responsive elements and iron homeostasis
14. Brain iron and behavior of rats are not normalized by treatment of iron deficiency anemia during early development
15. Characterization, receptor mapping and blood-brain barrier transcytosi of antibodies to the human transferrin receptor
16. Liver and brain iron deficiency in newborn infants with bilateral renal agenesis (Potter's syndrome)
17. Identification and localization of divalent metal transporter-1 (DMT-1) in term human placenta
18. Transferrin receptors in rat central nervous system. An immunocytochemical study
19. The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes
20. Iron regulates cytoplasmic levels of a novel iron-responsive element-binding protein without aconitase activity
21. Regulation of genes of iron metabolism by the ironresponsive proteins
22. Examination of blood-brain barrier transferrin receptor by confocal fluorescent microscopy of unfixed isolated rat brain capillaries
23. Importance of fetal and neonatal iron: Adequacy for normal development of central nervous system
24. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
25. Immunolocalization of iron regulatory protein expression in the murine central nervous system
26. Perinatal iron deficiency and the developing brain
27. Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy
28. Existing and emerging mechanisms for transport of iron and manganese to the brain
29. Transferrin and transferrin receptor function in brain barrier systems
30. Iron deficiency of liver, heart, and brain in newborn infants of diabetic mothers
31. Placental transferrin receptor in diabetic pregnancies with increased fetal iron demand
32. Variations in dietary iron alter brain iron metabolism in developing rats
33. Perinatal brain iron deficiency increases the vulnerability of rat hippocampus to hypoxic ischemic insult
34. Critical periods of vulnerability for the developing nervous system: Evidence from human and animal models
35. Iron, transferrin, and ferritin in the rat brain during development and aging
36. Storage iron in human foetal organs
37. Evidence for non-transferrin-mediated uptake and release of iron and manganese in glial cell cultures from hypotransferrinemic mice
38. Developmental changes in transferrin and iron uptake by the brain in the rat
39. Regulation and developmental expression of the divalent metal transporter in the rat brain