The antimitogenic effect of the cannabinoid receptor agonist WIN55212-2 on human melanoma cells is mediated by the membrane lipid raft

Cancer Letters

Volumn 310, Issue 2, 2011, Pages 240-249

  Scuderi, Mariagrazia Rita ^a   Cantarella, Giuseppina ^a   Scollo, Mimmo ^a   Lempereur, Laurence ^a   Palumbo, Marco ^a   Saccani Jotti, Gloria ^b   Bernardini, Renato ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

Author keywords

Cannabinoid; Cell death; Melanoma; Signal transduction; Therapy

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CASPASE; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; MESSENGER RNA; METHYL BETA CYCLODEXTRIN; MITOGEN ACTIVATED PROTEIN KINASE;

ANTIMITOGENIC EFFECT; ARTICLE; CANCER INHIBITION; CELL DEATH; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID RAFT; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

APOPTOSIS; BENZOXAZINES; CANNABINOIDS; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; MELANOMA; MEMBRANE MICRODOMAINS; MORPHOLINES; NAPHTHALENES; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; SIGNAL TRANSDUCTION;

EID: 80051683765     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.07.008     Document Type: Article

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