-
1
-
-
0025871477
-
Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons
-
Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol. Rev. 43 (1991) 143-201
-
(1991)
Pharmacol. Rev.
, vol.43
, pp. 143-201
-
-
Holzer, P.1
-
2
-
-
38549118896
-
Capsaicin (TRPV1 Agonist) therapy for pain relief: farewell or revival?
-
Knotkova H., Pappagallo M., and Szallasi A. Capsaicin (TRPV1 Agonist) therapy for pain relief: farewell or revival?. Clin. J. Pain 24 (2008) 142-154
-
(2008)
Clin. J. Pain
, vol.24
, pp. 142-154
-
-
Knotkova, H.1
Pappagallo, M.2
Szallasi, A.3
-
3
-
-
39449102203
-
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
-
Gunthorpe M.J., and Szallasi A. Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms. Curr. Pharm. Des. 14 (2008) 32-41
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 32-41
-
-
Gunthorpe, M.J.1
Szallasi, A.2
-
4
-
-
37549071810
-
The emerging role of TRPV1 in diabetes and obesity
-
Suri A., and Szallasi A. The emerging role of TRPV1 in diabetes and obesity. Trends Pharmacol. Sci. 29 (2008) 29-36
-
(2008)
Trends Pharmacol. Sci.
, vol.29
, pp. 29-36
-
-
Suri, A.1
Szallasi, A.2
-
5
-
-
57749192102
-
-
Roufogalis, B.D. and Dedov, V.N. (2000) in: Crubasik S. and Roufogalis, B.D. (Eds.) Herbal Medicinal Products for the Treatment of Pain, Australia, pp. 94-98.
-
Roufogalis, B.D. and Dedov, V.N. (2000) in: Crubasik S. and Roufogalis, B.D. (Eds.) Herbal Medicinal Products for the Treatment of Pain, Australia, pp. 94-98.
-
-
-
-
6
-
-
0032721391
-
Novel natural vanilloid receptor agonists: new therapeutic targets for drug development
-
Sterner O., and Szallasi A. Novel natural vanilloid receptor agonists: new therapeutic targets for drug development. Trends Pharmacol. Sci. 20 (1999) 459-465
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 459-465
-
-
Sterner, O.1
Szallasi, A.2
-
7
-
-
0032813348
-
Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances
-
Surh Y. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat. Res. 428 (1999) 305-327
-
(1999)
Mutat. Res.
, vol.428
, pp. 305-327
-
-
Surh, Y.1
-
8
-
-
26444511606
-
Structure and function of TRPV1
-
Tominaga M., and Tominaga T. Structure and function of TRPV1. Pflug. Arch. 451 (2005) 143-150
-
(2005)
Pflug. Arch.
, vol.451
, pp. 143-150
-
-
Tominaga, M.1
Tominaga, T.2
-
9
-
-
34247898927
-
Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells
-
Kim Y.M., Hwang J.T., Kwak D.W., Lee Y.K., and Park O.J. Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells. Ann. NY Acad. Sci. 1095 (2007) 496-503
-
(2007)
Ann. NY Acad. Sci.
, vol.1095
, pp. 496-503
-
-
Kim, Y.M.1
Hwang, J.T.2
Kwak, D.W.3
Lee, Y.K.4
Park, O.J.5
-
10
-
-
33947304343
-
TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells - mechanisms behind a possible new "hot" cancer treatment
-
Chow J., Norng M., Zhang J., and Chai J. TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells - mechanisms behind a possible new "hot" cancer treatment. Biochim. Biophys. Acta 1773 (2007) 565-576
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 565-576
-
-
Chow, J.1
Norng, M.2
Zhang, J.3
Chai, J.4
-
11
-
-
33749533243
-
Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation
-
Wu C.C., Lin J.P., Yang J.S., Chou S.T., Chen S.C., Lin Y.T., Lin H.L., and Chung J.G. Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma CE 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation. Mutat. Res. 601 (2006) 71-82
-
(2006)
Mutat. Res.
, vol.601
, pp. 71-82
-
-
Wu, C.C.1
Lin, J.P.2
Yang, J.S.3
Chou, S.T.4
Chen, S.C.5
Lin, Y.T.6
Lin, H.L.7
Chung, J.G.8
-
12
-
-
33846281508
-
Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death
-
Athanasiou A., et al. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochem. Biophys. Res. Commun. 354 (2007) 50-55
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.354
, pp. 50-55
-
-
Athanasiou, A.1
-
13
-
-
34047143134
-
Stimulation of sensory neurons by capsaicin increases tissue levels of IGF-I, thereby reducing reperfusion-induced apoptosis in mice
-
Harada N., Okajima K., Kurihara H., and Nakagata N. Stimulation of sensory neurons by capsaicin increases tissue levels of IGF-I, thereby reducing reperfusion-induced apoptosis in mice. Neuropharmacology 52 (2007) 1303-1311
-
(2007)
Neuropharmacology
, vol.52
, pp. 1303-1311
-
-
Harada, N.1
Okajima, K.2
Kurihara, H.3
Nakagata, N.4
-
14
-
-
0025286927
-
Effects of capsaicin on the metabolism of rheumatoid arthritis synoviocytes in vitro
-
Matucci-Cerinic M., Marabini S., Jantsch S., Cagnoni M., and Partsch G. Effects of capsaicin on the metabolism of rheumatoid arthritis synoviocytes in vitro. Ann. Rheum. Dis. 49 (1990) 598-602
-
(1990)
Ann. Rheum. Dis.
, vol.49
, pp. 598-602
-
-
Matucci-Cerinic, M.1
Marabini, S.2
Jantsch, S.3
Cagnoni, M.4
Partsch, G.5
-
15
-
-
36849065338
-
Putative cancer chemopreventive agents of dietary origin-how safe are they?
-
Verschoyle R.D., Steward W.P., and Gescher A.J. Putative cancer chemopreventive agents of dietary origin-how safe are they?. Nutr. Cancer 59 (2007) 152-162
-
(2007)
Nutr. Cancer
, vol.59
, pp. 152-162
-
-
Verschoyle, R.D.1
Steward, W.P.2
Gescher, A.J.3
-
16
-
-
0029928940
-
Capsaicin in hot chili pepper: carcinogen, co-carcinogen or anticarcinogen?
-
Surh Y.J., and Lee S.S. Capsaicin in hot chili pepper: carcinogen, co-carcinogen or anticarcinogen?. Food Chem. Toxicol. 34 (1996) 313-316
-
(1996)
Food Chem. Toxicol.
, vol.34
, pp. 313-316
-
-
Surh, Y.J.1
Lee, S.S.2
-
17
-
-
31444437266
-
Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin
-
Sanchez A.M., Sanchez M.G., Malagarie-Cazenave S., Olea N., and Diaz-Laviada I. Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin. Apoptosis 11 (2006) 89-99
-
(2006)
Apoptosis
, vol.11
, pp. 89-99
-
-
Sanchez, A.M.1
Sanchez, M.G.2
Malagarie-Cazenave, S.3
Olea, N.4
Diaz-Laviada, I.5
-
18
-
-
34848895758
-
Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation
-
Sanchez A.M., Malagarie-Cazenave S., Olea N., Vara D., Chiloeches A., and Diaz-Laviada I. Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation. Apoptosis 12 (2007) 2013-2024
-
(2007)
Apoptosis
, vol.12
, pp. 2013-2024
-
-
Sanchez, A.M.1
Malagarie-Cazenave, S.2
Olea, N.3
Vara, D.4
Chiloeches, A.5
Diaz-Laviada, I.6
-
20
-
-
2442538189
-
Role of FAN in tumor necrosis factor-alpha and lipopolysaccharide-induced interleukin-6 secretion and lethality in d-galactosamine-sensitized mice
-
Malagarie-Cazenave S., et al. Role of FAN in tumor necrosis factor-alpha and lipopolysaccharide-induced interleukin-6 secretion and lethality in d-galactosamine-sensitized mice. J. Biol. Chem. 279 (2004) 18648-18655
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18648-18655
-
-
Malagarie-Cazenave, S.1
-
22
-
-
4544368241
-
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel
-
Chuang H.H., Neuhausser W.M., and Julius D. The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron 43 (2004) 859-869
-
(2004)
Neuron
, vol.43
, pp. 859-869
-
-
Chuang, H.H.1
Neuhausser, W.M.2
Julius, D.3
-
23
-
-
34247523747
-
Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids
-
De Petrocellis L., Starowicz K., Moriello A.S., Vivese M., Orlando P., and Di Marzo V. Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. Exp. Cell Res. 313 (2007) 1911-1920
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 1911-1920
-
-
De Petrocellis, L.1
Starowicz, K.2
Moriello, A.S.3
Vivese, M.4
Orlando, P.5
Di Marzo, V.6
-
24
-
-
20344384533
-
Expression of the transient receptor potential vanilloid 1 (TRPV1) in LNCaP and PC-3 prostate cancer cells and in human prostate tissue
-
Sanchez M.G., Sanchez A.M., Collado B., Malagarie-Cazenave S., Olea N., Carmena M.J., Prieto J.C., and Diaz-Laviada I.I. Expression of the transient receptor potential vanilloid 1 (TRPV1) in LNCaP and PC-3 prostate cancer cells and in human prostate tissue. Eur. J. Pharmacol. 515 (2005) 20-27
-
(2005)
Eur. J. Pharmacol.
, vol.515
, pp. 20-27
-
-
Sanchez, M.G.1
Sanchez, A.M.2
Collado, B.3
Malagarie-Cazenave, S.4
Olea, N.5
Carmena, M.J.6
Prieto, J.C.7
Diaz-Laviada, I.I.8
-
25
-
-
0036695828
-
Ceramide in apoptosis: a revisited role
-
Levade T., Malagarie-Cazenave S., Gouaze V., Segui B., Tardy C., Betito S., Andrieu-Abadie N., and Cuvillier O. Ceramide in apoptosis: a revisited role. Neurochem. Res. 27 (2002) 601-607
-
(2002)
Neurochem. Res.
, vol.27
, pp. 601-607
-
-
Levade, T.1
Malagarie-Cazenave, S.2
Gouaze, V.3
Segui, B.4
Tardy, C.5
Betito, S.6
Andrieu-Abadie, N.7
Cuvillier, O.8
-
26
-
-
45849095200
-
The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca(2+) is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons
-
Tang H.B., and Nakata Y. The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca(2+) is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons. Naunyn Schmiedebergs Arch. Pharmacol. 377 (2008) 325-332
-
(2008)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.377
, pp. 325-332
-
-
Tang, H.B.1
Nakata, Y.2
-
27
-
-
35848954977
-
Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target
-
Joung E.J., Li M.H., Lee H.G., Somparn N., Jung Y.S., Na H.K., Kim S.H., Cha Y.N., and Surh Y.J. Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target. Antioxid. Redox Signal 9 (2007) 2087-2098
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 2087-2098
-
-
Joung, E.J.1
Li, M.H.2
Lee, H.G.3
Somparn, N.4
Jung, Y.S.5
Na, H.K.6
Kim, S.H.7
Cha, Y.N.8
Surh, Y.J.9
-
28
-
-
30444439079
-
Activation of protein kinase B/Akt signaling pathway contributes to mechanical hypersensitivity induced by capsaicin
-
Sun R.Q., Tu Y.J., Yan J.Y., and Willis W.D. Activation of protein kinase B/Akt signaling pathway contributes to mechanical hypersensitivity induced by capsaicin. Pain 120 (2006) 86-96
-
(2006)
Pain
, vol.120
, pp. 86-96
-
-
Sun, R.Q.1
Tu, Y.J.2
Yan, J.Y.3
Willis, W.D.4
-
29
-
-
33751549452
-
Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin in rats
-
Sun R., Yan J., and Willis W.D. Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin in rats. Neuroscience 144 (2007) 286-294
-
(2007)
Neuroscience
, vol.144
, pp. 286-294
-
-
Sun, R.1
Yan, J.2
Willis, W.D.3
-
30
-
-
34447623212
-
Activation of phosphatidylinositol 3-kinase and protein kinase B/Akt in dorsal root ganglia and spinal cord contributes to the neuropathic pain induced by spinal nerve ligation in rats
-
Xu J.T., Tu H.Y., Xin W.J., Liu X.G., Zhang G.H., and Zhai C.H. Activation of phosphatidylinositol 3-kinase and protein kinase B/Akt in dorsal root ganglia and spinal cord contributes to the neuropathic pain induced by spinal nerve ligation in rats. Exp. Neurol. 206 (2007) 269-279
-
(2007)
Exp. Neurol.
, vol.206
, pp. 269-279
-
-
Xu, J.T.1
Tu, H.Y.2
Xin, W.J.3
Liu, X.G.4
Zhang, G.H.5
Zhai, C.H.6
-
31
-
-
34548397326
-
Cross-talk between the androgen receptor and the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer
-
Wang Y., Kreisberg J.I., and Ghosh P.M. Cross-talk between the androgen receptor and the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer. Curr. Cancer Drug Targets 7 (2007) 591-604
-
(2007)
Curr. Cancer Drug Targets
, vol.7
, pp. 591-604
-
-
Wang, Y.1
Kreisberg, J.I.2
Ghosh, P.M.3
-
32
-
-
33645533257
-
Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells
-
Mori A., Lehmann S., O'Kelly J., Kumagai T., Desmond J.C., Pervan M., McBride W.H., Kizaki M., and Koeffler H.P. Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells. Cancer Res. 66 (2006) 3222-3229
-
(2006)
Cancer Res.
, vol.66
, pp. 3222-3229
-
-
Mori, A.1
Lehmann, S.2
O'Kelly, J.3
Kumagai, T.4
Desmond, J.C.5
Pervan, M.6
McBride, W.H.7
Kizaki, M.8
Koeffler, H.P.9
-
33
-
-
0034465259
-
Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation
-
Melck D., De Petrocellis L., Orlando P., Bisogno T., Laezza C., Bifulco M., and Di Marzo V. Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. Endocrinology 141 (2000) 118-126
-
(2000)
Endocrinology
, vol.141
, pp. 118-126
-
-
Melck, D.1
De Petrocellis, L.2
Orlando, P.3
Bisogno, T.4
Laezza, C.5
Bifulco, M.6
Di Marzo, V.7
-
34
-
-
2442660100
-
Molecular architecture of the vanilloid receptor. Insights for drug design
-
Ferrer-Montiel A., Garcia-Martinez C., Morenilla-Palao C., Garcia-Sanz N., Fernandez-Carvajal A., Fernandez-Ballester G., and Planells-Cases R. Molecular architecture of the vanilloid receptor. Insights for drug design. Eur. J. Biochem. 271 (2004) 1820-1826
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 1820-1826
-
-
Ferrer-Montiel, A.1
Garcia-Martinez, C.2
Morenilla-Palao, C.3
Garcia-Sanz, N.4
Fernandez-Carvajal, A.5
Fernandez-Ballester, G.6
Planells-Cases, R.7
-
35
-
-
8544233547
-
Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells
-
Zhang L., and Barritt G.J. Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells. Cancer Res. 64 (2004) 8365-8373
-
(2004)
Cancer Res.
, vol.64
, pp. 8365-8373
-
-
Zhang, L.1
Barritt, G.J.2
-
36
-
-
33847037469
-
Differential role of TRP channels in prostate cancer
-
Prevarskaya N., Flourakis M., Bidaux G., Thebault S., and Skryma R. Differential role of TRP channels in prostate cancer. Biochem. Soc. Trans. 35 (2007) 133-135
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 133-135
-
-
Prevarskaya, N.1
Flourakis, M.2
Bidaux, G.3
Thebault, S.4
Skryma, R.5
-
37
-
-
34547420154
-
TRPs in bladder diseases
-
Birder L.A. TRPs in bladder diseases. Biochim. Biophys. Acta 1772 (2007) 879-884
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 879-884
-
-
Birder, L.A.1
|