The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in scaffold attachment factor B1 deficient mice

Aging

Volumn 3, Issue 3, 2011, Pages 277-290

  Lachapelle, Sophie ^a   Oesterreich, Steffi ^b   Lebel, Michel ^a  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Immortalization; Scaffold attachment factor B1; Senescence; Werner syndrome

Indexed keywords

DNA BINDING PROTEIN; ESTROGEN RECEPTOR; EXODEOXYRIBONUCLEASE; MATRIX ATTACHMENT REGION BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEAR MATRIX PROTEIN; PROTEIN KINASE C DELTA; RECQ HELICASE; RNA BINDING PROTEIN; SAFB PROTEIN, HUMAN; SCAFFOLD ATTACHMENT FACTOR B1, MOUSE; WRN PROTEIN, HUMAN; WRN PROTEIN, MOUSE;

129 MOUSE; ANIMAL; APOPTOSIS; ARTICLE; C57BL MOUSE; CELL PROLIFERATION; CELL STRAIN HEK293; CELL SURVIVAL; DOUBLE STRANDED DNA BREAK; EXPERIMENTAL NEOPLASM; FEMALE; GENETICS; HOMOZYGOTE; HUMAN; LONGEVITY; LUNG; MALE; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; WERNER SYNDROME;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; DNA BREAKS, DOUBLE-STRANDED; DNA-BINDING PROTEINS; EXODEOXYRIBONUCLEASES; FEMALE; HEK293 CELLS; HOMOZYGOTE; HUMANS; LONGEVITY; LUNG; MALE; MATRIX ATTACHMENT REGION BINDING PROTEINS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASMS, EXPERIMENTAL; NUCLEAR MATRIX-ASSOCIATED PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PREGNANCY; PROTEIN KINASE C-DELTA; RECEPTORS, ESTROGEN; RECQ HELICASES; RNA-BINDING PROTEINS; WERNER SYNDROME;

EID: 80051648993     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100300     Document Type: Article

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