메뉴 건너뛰기




Volumn 118, Issue 1-2, 2003, Pages 60-71

Quantifying mRNA in postmortem human brain: Influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance

Author keywords

Alzheimer's disease; Confounding factors; Human brain; mRNA; Quantification; TaqMan

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA ACTIN; CYCLOPHILIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; NEURON SPECIFIC ENOLASE;

EID: 0141957335     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(03)00337-1     Document Type: Article
Times cited : (173)

References (22)
  • 6
    • 0004236701 scopus 로고
    • Experimental Designs
    • New York: Wiley
    • Cochran W.G., Cox G.M. Experimental Designs. 2nd ed. 1957;Wiley, New York.
    • (1957) 2nd ed.
    • Cochran, W.G.1    Cox, G.M.2
  • 7
    • 0029964835 scopus 로고    scopus 로고
    • A novel method for real time quantitative RT-PCR
    • Gibson U.E., Heid C.A., Williams P.M. A novel method for real time quantitative RT-PCR. Genome Res. 6:1996;995-1001.
    • (1996) Genome Res. , vol.6 , pp. 995-1001
    • Gibson, U.E.1    Heid, C.A.2    Williams, P.M.3
  • 8
    • 0021921539 scopus 로고
    • The patients dying after long terminal phase have acidotic brains; Implications for biochemical measurements on autopsy tissue
    • Hardy J.A., Wester P., Winblad B., Gezelius C., Bring G., Eriksson A. The patients dying after long terminal phase have acidotic brains; implications for biochemical measurements on autopsy tissue. J. Neural Transm. 61:1985;253-264.
    • (1985) J. Neural Transm. , vol.61 , pp. 253-264
    • Hardy, J.A.1    Wester, P.2    Winblad, B.3    Gezelius, C.4    Bring, G.5    Eriksson, A.6
  • 10
    • 0028178079 scopus 로고
    • The effects of Alzheimer's disease, other dementias, and premortem course on beta-amyloid precursor protein messenger RNA in frontal cortex
    • Harrison P.J., Barton A.J., Procter A.W., Bowen D.M., Pearson R.C. The effects of Alzheimer's disease, other dementias, and premortem course on beta-amyloid precursor protein messenger RNA in frontal cortex. J. Neurochem. 62:1994;635-644.
    • (1994) J. Neurochem. , vol.62 , pp. 635-644
    • Harrison, P.J.1    Barton, A.J.2    Procter, A.W.3    Bowen, D.M.4    Pearson, R.C.5
  • 11
    • 0028845078 scopus 로고
    • The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: Selective mRNA vulnerability and comparison with their encoded proteins
    • Harrison P.J., Heath P.R., Eastwood S.L., Burnet P.W., McDonald B., Pearson R.C. The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: selective mRNA vulnerability and comparison with their encoded proteins. Neurosci. Lett. 200:1995;151-154.
    • (1995) Neurosci. Lett. , vol.200 , pp. 151-154
    • Harrison, P.J.1    Heath, P.R.2    Eastwood, S.L.3    Burnet, P.W.4    McDonald, B.5    Pearson, R.C.6
  • 13
    • 0029396761 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease
    • Hulette C., Mirra S., Wilkinson W., Heyman A., Fillenbaum G., Clark C. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease. Neurology. 45:1995;1991-1995.
    • (1995) Neurology , vol.45 , pp. 1991-1995
    • Hulette, C.1    Mirra, S.2    Wilkinson, W.3    Heyman, A.4    Fillenbaum, G.5    Clark, C.6
  • 14
    • 0030668729 scopus 로고    scopus 로고
    • Multivariate analysis of RNA levels from postmortem human brains as measured by three different methods of RT-PCR
    • Johnston N.L., Cervenak J., Shore A.D., Torrey E.F., Yolken R.H., Cerevnak J. Multivariate analysis of RNA levels from postmortem human brains as measured by three different methods of RT-PCR. J. Neurosci. Methods. 77:1997;83-92.
    • (1997) J. Neurosci. Methods , vol.77 , pp. 83-92
    • Johnston, N.L.1    Cervenak, J.2    Shore, A.D.3    Torrey, E.F.4    Yolken, R.H.5    Cerevnak, J.6
  • 16
    • 0031910311 scopus 로고    scopus 로고
    • Advances in quantitative PCR technology: 5′ nuclease assays
    • Lie Y.S., Petropoulos C.J. Advances in quantitative PCR technology: 5′ nuclease assays. Curr. Opin. Biotechnol. 9:1998;43-48.
    • (1998) Curr. Opin. Biotechnol. , vol.9 , pp. 43-48
    • Lie, Y.S.1    Petropoulos, C.J.2
  • 17
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 34:1984;939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 18
    • 0033637841 scopus 로고    scopus 로고
    • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
    • Mirnics K., Middleton F., Marquez A., Lewis D.A., Levitt P. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron. 28:2000;53-67.
    • (2000) Neuron , vol.28 , pp. 53-67
    • Mirnics, K.1    Middleton, F.2    Marquez, A.3    Lewis, D.A.4    Levitt, P.5
  • 19
    • 0020611062 scopus 로고
    • Human brain neurochemistry - Some postmortem problems
    • Perry E.K., Perry R.H. Human brain neurochemistry - some postmortem problems. Life Sci. 33:1983;1733-1743.
    • (1983) Life Sci. , vol.33 , pp. 1733-1743
    • Perry, E.K.1    Perry, R.H.2
  • 20
    • 0026683675 scopus 로고
    • On the stability of messenger RNA and ribosomal RNA in the brains of control human subjects and patients with Alzheimer's disease
    • Ross B.M., Knowler J.T., McCulloch J. On the stability of messenger RNA and ribosomal RNA in the brains of control human subjects and patients with Alzheimer's disease. J. Neurochem. 58:1992;1810-1819.
    • (1992) J. Neurochem. , vol.58 , pp. 1810-1819
    • Ross, B.M.1    Knowler, J.T.2    McCulloch, J.3
  • 21
    • 0027218078 scopus 로고
    • Problems related to the interpretation of autoradiographic data on gene expression using common constitutive transcripts as controls
    • Spanakis E. Problems related to the interpretation of autoradiographic data on gene expression using common constitutive transcripts as controls. Nucleic Acids Res. 21:1993;3809-3819.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 3809-3819
    • Spanakis, E.1
  • 22
    • 0028279284 scopus 로고
    • Evaluation of quantitative variation in gene expression
    • Spanakis E., Brouty-Boye D. Evaluation of quantitative variation in gene expression. Nucleic Acids Res. 22:1994;799-806.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 799-806
    • Spanakis, E.1    Brouty-Boye, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.