Cobalt-catalyzed alkenylation of thiazoles with alkynes via C-H bond functionalization

Synthesis

Volumn , Issue 16, 2011, Pages 2561-2566

  Ding, Zhenhua ^a   Yoshikai, Naohiko ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

alkynes; C H activation; cobalt; heterocycles; hydroarylation

Indexed keywords

ALKYNES; C-H ACTIVATION; C-H BOND; FUNCTIONALIZATIONS; HETEROCYCLES; HYDROARYLATION; INTERNAL ALKYNES; SYN-ADDITION;

ACETYLENE; ACTIVATION ANALYSIS;

COBALT;

2 (DEC 5 EN 5 YL) 4,5 DIMETHYLTHIAZOLE; 2 (OCT 4 EN 4 YL) 5 (4 TOLYL)THIAZOLE; 2 (OCT 4 EN 4 YL) 5 [2 (TRIFLUOROMETHYL)PHENYL]THIAZOLE; 2 (OCT 4 EN 4 YL) 5 [4 (THIAZOL 5 YL)PHENYL]OXAZOLE; 2 (OCT 4 EN 4 YL) 5 PHENYLTHIAZOLE; 4 [2 (1,2 DIPHENYLVINYL) 4 METHYLTHIAZOL 5 YL]BENZONITRILE; 4 [2 (HEX 2 EN 2 YL) 4 METHYLTHIAZOL 5 YL]BENZONITRILE; 4 [2 (HEX 2 EN 3 YL) 4 METHYLTHIAZOL 5 YL]BENZONITRILE; 4 [4 METHYL 2 (1 PHENYLPROP 1 EN 2 YL)THIAZOL 5 YL]BENZONITRILE; 4 [4 METHYL 2 (OCT 4 EN 4 YL)THIAZOL 5 YL]BENZONITRILE; 4,5 DIMETHYL 2 (4 METHYLPENT 2 EN 2 YL)THIAZOLE; 4,5 DIMETHYL 2 (OCT 4 EN 4 YL)THIAZOLE; 5 (2 FLUOROPHENYL) 2 (OCT 4 EN 4 YL)THIAZOLE; 5 (2 FLUOROPHENYL)THIAZOLE; 5 (4 METHOXYPHENYL) 2 (OCT 4 EN 4 YL)THIAZOLE; 5 [2 (BENZYLOXY)ETHYL] 4 METHYL 2 (OCT 4 EN 4 YL)THIAZOLE; 5 [2 (TRIFLUOROMETHYL)PHENYL]THIAZOLE; 5 [4 (THIAZOL 5 YL)PHENYL]OXAZOLE; 5 [4 [2 (OCT 4 EN 4 YL)THIAZOL 5 YL]PHENYL]OXAZOLE; ALKYNE; COBALT; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; HIGH RESOLUTION MELTING ANALYSIS; HYDROGEN BOND; MELTING POINT; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS;

EID: 80051552692     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260077     Document Type: Article

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