The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities

International Journal of Cancer

Volumn 121, Issue 8, 2007, Pages 1839-1846

  Zhu, Jia Y ^a   Lavrik, Inna N ^a   Mahlknecht, Ulrich ^b   Giaisi, Marco ^a   Proksch, Peter ^c   Krammer, Peter H ^a   Li Weber, Min ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Apoptosis; Bid; ERK; JNK; Leukemia; p38

Indexed keywords

CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; CHINESE DRUG; FAS ASSOCIATED DEATH DOMAIN PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN BID; ROCAGLAMIDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

AGLAIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CHINESE HERB; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL;

ACUTE DISEASE; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOFURANS; CELL LINE, TUMOR; DRUGS, CHINESE HERBAL; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEUKEMIA; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOID; LEUKEMIA, MYELOID, CHRONIC; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TUBULIN;

EID: 34548676362     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22883     Document Type: Article

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