The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte

Rheumatology International

Volumn 31, Issue 1, 2011, Pages 53-60

  He, Ya ^a   Fan, Jinjin ^a   Lin, Haobo ^a   Yang, Xiuyan ^a   Ye, Yujin ^a   Liang, Liuqin ^a   Zhan, Zhongping ^a   Dong, Xiuqing ^a   Sun, Lin ^b   Xu, Hanshi ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Angiogenesis; Artesunate; Fibroblast like synoviocytes; Rheumatoid arthritis; Signal transduction

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTIMALARIAL AGENT; ARTESUNATE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FIBROBLAST; FIBROBLAST LIKE SYNOVIOCYTE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; WESTERN BLOTTING;

ADULT; ANTIMALARIALS; ARTEMISININS; ARTHRITIS, RHEUMATOID; BLOTTING, WESTERN; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FLOW CYTOMETRY; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-8; MIDDLE AGED; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; SYNOVIAL MEMBRANE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 78751582382     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-009-1218-7     Document Type: Article

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