A Src family kinase inhibitor improves survival in experimental acute liver failure associated with elevated cerebral and circulating vascular endothelial growth factor levels

Liver International

Volumn 31, Issue 8, 2011, Pages 1222-1230

  Aspinall, Richard J ^a,b   Weis, Sara M ^b   Barnes, Leo ^b   Lutu Fuga, Kimberly ^b   Bylund, David J ^a   Pockros, Paul J ^a   Cheresh, David A ^b  

^a SCRIPPS CLINIC   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Acute liver failure; Ammonia; Azoxymethane; Bosutinib; Encephalopathy; Src; VEGF

Indexed keywords

AMMONIA; AZOXYMETHANE; BOSUTINIB; GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN; PROTEIN TYROSINE KINASE INHIBITOR; VASCULOTROPIN;

ACUTE LIVER FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BLOOD LEVEL; BRAIN DISEASE; BRAIN LEVEL; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HYPERAMMONEMIA; IMMUNOHISTOCHEMISTRY; LIVER INJURY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SURVIVAL;

AMMONIUM CHLORIDE; ANILINE COMPOUNDS; ANIMALS; APOPTOSIS; ASTROCYTES; AZOXYMETHANE; BRAIN; BRAIN EDEMA; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL GROWTH FACTORS; GREEN FLUORESCENT PROTEINS; HEPATIC ENCEPHALOPATHY; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE, ACUTE; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRILES; PEPTIDES, CYCLIC; PROTEIN KINASE INHIBITORS; QUINOLINES; RECOMBINANT FUSION PROTEINS; SRC-FAMILY KINASES; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79961210349     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02554.x     Document Type: Article

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