Multiorgan failure is the commonest cause of death in fulminant hepatic failure: A single centre experience [1]

Liver International

Volumn 24, Issue 6, 2004, Pages 702-703

  Boeckx, Nicholas Karel ^a   Haydon, Geoffrey ^a   Rusli, Ferry ^a   Murphy, Nick ^a  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; PARACETAMOL;

ADULT; AGED; AUTOPSY; BRAIN EDEMA; CAUSE OF DEATH; CLINICAL FEATURE; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG OVERDOSE; FEMALE; HEPATIC ENCEPHALOPATHY; HUMAN; INTRACRANIAL HYPERTENSION; KIDNEY FAILURE; LETTER; LIVER FAILURE; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIPLE ORGAN FAILURE; PRACTICE GUIDELINE; RECORDING; RESPIRATORY FAILURE; SEPSIS; TREATMENT OUTCOME; UNITED KINGDOM;

ADULT; AGE DISTRIBUTION; AGED; CAUSE OF DEATH; FEMALE; GREAT BRITAIN; HEPATIC ENCEPHALOPATHY; HOSPITALS, URBAN; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; REGISTRIES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEX DISTRIBUTION;

EID: 11144317782     PISSN: 14783223     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2004.0968.x     Document Type: Letter

References (5)

1. O'Grady J G, Gimson A E, O'Brien C J, Pucknell A, Hughes R D, Williams R. Controlled trials of charcoal hemoperfusion and prognostic factors in fulminant hepatic failure. Gastroenterology 1988; 94: 1186-92.
2. Makin A J, Wendon J, Williams R. A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993). Gastroenterology 1995; 109: 1907-16.
3. Harrison P M, Keays R, Bray G P, Alexander G J M, Williams R. Improved outcome of paracetomol-induced fulminant hepatic failure by late administration of acetylcysteine. Lancet 1990; 335: 1572-3.
4. Keays R, Harrison P M, Wendon J, et al. Intravenous acetylcysteine in paracetomol induced fulminant hepatic failure: a prospective controlled trial. Br Med J 1991; 303: 1026-9.
5. Mutimer D J, Ayres R C S, Neuberger J M, Davies M H, Holguin J, Buckels J A C, Mayer A D, MacMaster P, Elias E. Serious paracetomol poisoning and the results of liver transplantation. Gut 1994; 35: 809-14.