Adeno-associated virus type 2 infection activates caspase dependent and independent apoptosis in multiple breast cancer lines but not in normal mammary epithelial cells

Molecular Cancer

Volumn 10, Issue , 2011, Pages

  Alam, Samina ^a   Bowser, Brian S ^a   Conway, Michael J ^b   Israr, Mohd ^a   Tandon, Apurva ^c   Meyers, Craig ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

AAV2; Adeno Associated Virus Type 2; Apoptosis; Breast cancer; c Myc; Cell cycle; Pro apoptotic therapeutics; Rep proteins

Indexed keywords

CASPASE 8; CASPASE 9; ENDONUCLEASE; KI 67 ANTIGEN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN REP40; VIRUS PROTEIN REP68; VIRUS PROTEIN REP78; CASPASE; DNA BINDING PROTEIN; REP PROTEINS, ADENO ASSOCIATED VIRUS 2; REP PROTEINS, ADENO-ASSOCIATED VIRUS 2;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 2; ADENO ASSOCIATED VIRUS 2 INFECTION; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENOMICS; HUMAN; HUMAN CELL; HUMAN TISSUE; ONCOGENE C MYC; PARVOVIRUS INFECTION; PROTEIN EXPRESSION; UPREGULATION; BREAST TUMOR; CARCINOMA; CELL CULTURE; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; MAMMARY GLAND; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL LINE; VIROLOGY; VIRUS GENOME; VIRUS REPLICATION;

ADENO-ASSOCIATED VIRUS - 2; HUMAN PAPILLOMAVIRUS;

APOPTOSIS; BREAST NEOPLASMS; CARCINOMA; CASPASES; CELL LINE, TUMOR; CELLS, CULTURED; DEPENDOVIRUS; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HUMANS; MAMMARY GLANDS, HUMAN; PARVOVIRIDAE INFECTIONS; TRANSDUCTION, GENETIC; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 79961131548     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-10-97     Document Type: Article

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