Sulindac induces apoptotic cell death in susceptible human breast cancer cells through, at least in part, inhibition of IKKβ

Apoptosis

Volumn 14, Issue 7, 2009, Pages 913-922

  Seo, A Mi ^a   Hong, Seung Woo ^b,c   Shin, Jae Sik ^c   Park, In Chul ^d   Hong, Nam Joo ^e   Kim, Dae Jin ^f   Lee, Won Keun ^b   Lee, Wang Jae ^c   Jin, Dong Hoon ^c   Lee, Myeong Sok ^a  

^a Sookmyung Women's University   (South Korea)

^b Myong Ji University   (South Korea)

^c Seoul National University   (South Korea)

^d Korea Institute of Radiation and Medical Science   (South Korea)

^e Yeungnam University   (South Korea)

^f Chung Ang University   (South Korea)

Author keywords

Apoptosis; IKK ; JNK1; NSAIDs; P38 MAPK; Sulindac

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CASPASE 9; I KAPPA B KINASE BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; SULINDAC;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; FEMALE; HUMANS; I-KAPPA B KINASE; MITOGEN-ACTIVATED PROTEIN KINASE 8; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, SMALL INTERFERING; SULINDAC;

EID: 67649586668     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0367-1     Document Type: Article

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