Adeno-associated virus type 2 induces apoptosis in human papillomavirus-infected cell lines but not in normal keratinocytes

Journal of Virology

Volumn 83, Issue 19, 2009, Pages 10286-10292

  Alam, Samina ^a   Meyers, Craig ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA; HELICASE; ONCOLYTIC ADENOVIRUS; PROTEIN E7;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS TYPE 2; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL LINE; CONTROLLED STUDY; GENOME; HUMAN; HUMAN CELL; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; WART VIRUS;

APOPTOSIS; BIOPSY; CASPASE 3; CELL LINE; DEPENDOVIRUS; DNA; FEMALE; FLOW CYTOMETRY; HUMANS; KERATINOCYTES; MODELS, BIOLOGICAL; PAPILLOMAVIRIDAE; PHOSPHORYLATION; RETINOBLASTOMA PROTEIN; UTERINE CERVICAL NEOPLASMS;

ADENO-ASSOCIATED VIRUS - 2; HUMAN PAPILLOMAVIRUS;

EID: 70349267557     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00343-09     Document Type: Article

References (42)

1. Alam, S., E. Sen, H. Brashear, and C. Meyers. 2006. Adeno-associated virus type 2 increases proteosome-dependent degradation of p21WAF1 in a human papillomavirus type 31b-positive cervical carcinoma line. J. Virol. 80:4927-4939.
2. Bantel-Schaal, U. 1995. Growth properties of a human melanoma cell line are altered by adeno-associated parvovirus type 2. Int. J. Cancer 60:269-274.
3. Bantel-Schaal, U., and M. Stohr. 1992. Influence of adeno-associated virus on adherence and growth properties of normal cells. J. Virol. 66:773-779.
4. Batchu, R. B., M. A. Shammas, J. Y. Wang, J. Freeman, N. Rosen, and N. C. Munshi. 2002. Adeno-associated virus protects the retinoblastoma family of proteins from adenoviral-induced functional inactivation. Cancer Res. 62:2982-2985.
5. Batchu, R. B., M. A. Shammas, J. Y. Wang, and N. C. Munshi. 2001. Dual level inhibition of E2F-1 activity by adeno-associated virus Rep78. J. Biol. Chem. 276:24315-24322.
6. Bedell, M. A., J. B. Hudson, T. R. Golub, M. E. Turyk, M. Hosken, G. D. Wilbanks, and L. A. Laimins. 1991. Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation. J. Virol. 65:2254-2260.
7. Bell, L. A., and K. M. Ryan. 2004. Life and death decisions by E2F-1. Cell Death Differ. 11:137-142.
8. Berns, K. I., and C. Giraud. 1996. Biology of adeno-associated virus. Curr. Top. Microbiol. Immunol. 218:1-23.
9. Berthet, C., K. Raj, P. Saudan, and P. Beard. 2005. How adeno-associated virus Rep78 protein arrests cells completely in S phase. Proc. Natl. Acad. Sci. USA 102:13634-13639.
10. Brady, H. J., and G. Gil-Gomez. 1999. The cell cycle and apoptosis. Results Probl. Cell Differ. 23:127-144.
11. Casto, B. C., J. A. Armstrong, R. W. Atchison, and W. M. Hammon. 1967. Studies on the relationship between adeno-associated virus type 1 (AAV-1) and adenoviruses. II. Inhibition of adenovirus plaques by AAV; its nature and specificity. Virology 33:452-458.
12. Chenuet, S., D. Martinet, N. Besuchet-Schmutz, M. Wicht, N. Jaccard, A. C. Bon, M. Derouazi, D. L. Hacker, J. S. Beckmann, and F. M. Wurm. 2008. Calcium phosphate transfection generates mammalian recombinant cell lines with higher specific productivity than polyfection. Biotechnol. Bioeng. 101:937-945.
13. Detjen, K. M., D. Murphy, M. Welzel, K. Farwig, B. Wiedenmann, and S. Rosewicz. 2003. Downregulation of p21(waf/cip-1) mediates apoptosis of human hepatocellular carcinoma cells in response to interferon-gamma. Exp. Cell Res. 282:78-89.
14. Elmore, S. 2007. Apoptosis: a review of programmed cell death. Toxicol. Pathol. 35:495-516.
15. Georg-Fries, B., S. Biederlack, J. Wolf, and H. zur Hausen. 1984. Analysis of proteins, helper dependence, and seroepidemiology of a new human parvovirus. Virology 134:64-71.
16. Gil-Gomez, G., A. Berns, and H. J. Brady. 1998. A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis. EMBO J. 17:7209-7218. (Pubitemid 29002690)
17. Han, L., T. H. Parmley, S. Keith, K. J. Kozlowski, L. J. Smith, and P. L. Hermonat. 1996. High prevalence of adeno-associated virus (AAV) type 2 rep DNA in cervical materials: AAV may be sexually transmitted. Virus Genes 12:47-52. (Pubitemid 26280623)
18. Hermanns, J., A. Schulze, P. Jansen-Dürr, J. A. Kleinschmidt, R. Schmidt, and H. zur Hausen. 1997. Infection of primary cells by adeno-associated virus type 2 results in a modulation of cell cycle-regulating proteins. J. Virol. 71:6020-6027.
19. Hermonat, P. L. 1994. Adeno-associated virus inhibits human papillomavirus type 16: a viral interaction implicated in cervical cancer. Cancer Res. 54:2278-2281.
20. Horer, M., S. Weger, K. Butz, F. Hoppe-Seyler, C. Geisen, and J. A. Kleinschmidt. 1995. Mutational analysis of adeno-associated virus Rep. protein-mediated inhibition of heterologous and homologous promoters. J. Virol. 69:5485-5496.
21. Im, D. S., and N. Muzyczka. 1990. The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity. Cell 61:447-457. (Pubitemid 20168999)
22. Inoue, Y., M. Kitagawa, and Y. Taya. 2007. Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage. EMBO J. 26:2083-2093. (Pubitemid 46625787)
23. Kube, D. M., S. Ponnazhagan, and A. Srivastava. 1997. Encapsidation of adeno-associated virus type 2 Rep proteins in wild-type and recombinant progeny virions: Rep-mediated growth inhibition of primary human cells. J. Virol. 71:7361-7371.
24. Leonard, C. J., and K. I. Berns. 1994. Cloning, expression, and partial purification of Rep78: an adeno-associated virus replication protein. Virology 200:566-573. (Pubitemid 24146532)
25. Li, Y., C. W. Jenkins, M. A. Nichols, and Y. Xiong. 1994. Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21. Oncogene 9:2261-2268. (Pubitemid 24228676)
26. Markham, D., S. Munro, J. Soloway, D. P. O'Connor, and N. B. La Thangue. 2006. DNA-damage-responsive acetylation of pRb regulates binding to E2F-1. EMBO Rep. 7:192-198.
27. Mayor, H. D., S. Drake, J. Stahmann, and D. M. Mumford. 1976. Antibodies to adeno-associated satellite virus and herpes simplex in sera from cancer patients and normal adults. Am. J. Obstet. Gynecol. 126:100-104.
28. McLaughlin-Drubin, M. E., N. D. Christensen, and C. Meyers. 2004. Propagation, infection, and neutralization of authentic HPV16 virus. Virology 322:213-219.
29. Meyers, C., S. Alam, M. Mane, and P. L. Hermonat. 2001. Altered biology of adeno-associated virus type 2 and human papillomavirus during dual infection of natural host tissue. Virology 287:30-39. (Pubitemid 32778236)
30. Munger, K., M. Scheffner, J. M. Huibregtse, and P. M. Howley. 1992. Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products. Cancer Surv. 12:197-217.
31. Nash, K., W. Chen, M. Salganik, and N. Muzyczka. 2009. Identification of cellular proteins that interact with the adeno-associated virus Rep protein. J. Virol. 83:454-469.
32. Ogston, P., K. Raj, and P. Beard. 2000. Productive replication of adenoassociated virus can occur in human papillomavirus type 16 (HPV-16) episome- containing keratinocytes and is augmented by the HPV-16 E2 protein. J. Virol. 74:3494-3504. (Pubitemid 30180291)
33. Pham, P. L., A. Kamen, and Y. Durocher. 2006. Large-scale transfection of mammalian cells for the fast production of recombinant protein. Mol. Biotechnol. 34:225-237.
34. Rader, J. S., T. R. Golub, J. B. Hudson, D. Patel, M. A. Bedell, and L. A. Laimins. 1990. In vitro differentiation of epithelial cells from cervical neoplasias resembles in vivo lesions. Oncogene 5:571-576.
35. Raj, K., P. Ogston, and P. Beard. 2001. Virus-mediated killing of cells that lack p53 activity. Nature 412:914-917. (Pubitemid 32821736)
36. Saudan, P., J. Vlach, and P. Beard. 2000. Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb. EMBO J. 19:4351-4361. (Pubitemid 30623746)
37. Schlehofer, J. R. 1994. The tumor suppressive properties of adeno-associated viruses. Mutat. Res. 305:303-313.
38. Schmidt, M., S. Afione, and R. M. Kotin. 2000. Adeno-associated virus type 2 Rep78 induces apoptosis through caspase activation independently of p53. J. Virol. 74:9441-9450. (Pubitemid 30746793)
39. Suganuma, M., T. Kawabe, H. Hori, T. Funabiki, and T. Okamoto. 1999. Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation. Cancer Res. 59:5887-5891. (Pubitemid 30004945)
40. Timpe, J. M., K. C. Verrill, B. N. Black, H. F. Ding, and J. P. Trempe. 2007. Adeno-associated virus induces apoptosis during coinfection with adenovirus. Virology 358:391-401. (Pubitemid 46138114)
41. Walz, C., A. Deprez, T. Dupressoir, M. Durst, M. Rabreau, and J. R. Schlehofer. 1997. Interaction of human papillomavirus type 16 and adeno-associated virus type 2 co-infecting human cervical epithelium. J. Gen. Virol. 78:1441-1452.
42. Winocour, E., M. F. Callaham, and E. Huberman. 1988. Perturbation of the cell cycle by adeno-associated virus. Virology 167:393-399. (Pubitemid 19037133)