메뉴 건너뛰기




Volumn 108, Issue 4, 2011, Pages 599-606

The link between erectile and cardiovascular health: The canary in the coal mine

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; ARGININE; ASCORBIC ACID; CALCIUM; CITRULLINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FOLIC ACID; GINSENG EXTRACT; INSULIN; IRBESARTAN; LOSARTAN; NITRIC OXIDE; OMEGA 3 FATTY ACID; PLACEBO; PYCNOGENOL; SILDENAFIL; TADALAFIL; TESTOSTERONE; VALSARTAN;

EID: 79960930303     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2011.03.093     Document Type: Review
Times cited : (71)

References (92)
  • 1
    • 0026353632 scopus 로고
    • Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission
    • Rajfer J, Aronson WJ, Bush PA, Dorey FJ, Ignarro LJ. Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission. N Engl J Med 1992; 326:90-94.
    • (1992) N Engl J Med , vol.326 , pp. 90-94
    • Rajfer, J.1    Aronson, W.J.2    Bush, P.A.3    Dorey, F.J.4    Ignarro, L.J.5
  • 2
    • 69949111623 scopus 로고    scopus 로고
    • Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases
    • Napoli C, Ignarro LJ. Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases. Arch Pharm Res 2009;32:1103-1108.
    • (2009) Arch Pharm Res , vol.32 , pp. 1103-1108
    • Napoli, C.1    Ignarro, L.J.2
  • 3
    • 1942516957 scopus 로고    scopus 로고
    • Heart disease risk factors predict erectile dysfunction 25 years later: The Rancho Bernardo Study
    • DOI 10.1016/j.jacc.2003.11.041, PII S0735109704001871
    • Fung MM, Bettencourt R, Barrett-Connor E. Heart disease risk factors predict erectile dysfunction 25 years later: the Rancho Bernardo Study. J Am Coll Cardiol 2004;43:1405-1411. (Pubitemid 38496346)
    • (2004) Journal of the American College of Cardiology , vol.43 , Issue.8 , pp. 1405-1411
    • Fung, M.M.1    Bettencourt, R.2    Barrett-Connor, E.3
  • 7
    • 33847399655 scopus 로고    scopus 로고
    • A retrospective study of the relationship between biomarkers of atherosclerosis and erectile dysfunction in 988 men
    • DOI 10.1038/sj.ijir.3901519, PII 3901519
    • Eaton CB, Liu YL, Mittleman MA, Miner M, Glasser DB, Rimm EB. A retrospective study of the relationship of biomarkers of atherosclerosis and erectile dysfunction in 988 men. Int J Impot Res 2007;19:218-225. (Pubitemid 46340843)
    • (2007) International Journal of Impotence Research , vol.19 , Issue.2 , pp. 218-225
    • Eaton, C.B.1    Liu, Y.L.2    Mittleman, M.A.3    Miner, M.4    Glasser, D.B.5    Rimm, E.B.6
  • 8
    • 10744225276 scopus 로고    scopus 로고
    • Erectile dysfunction prevalence, time of onset and association with risk factors in 300 consecutive patients with acute chest pain and angiographically documented coronary artery disease
    • Montorsi F, Briganti A, Salonia A, Rigatti P, Margonato A, Macchi A, Galli S, Ravagnani PM, Montorsi P. Erectile dysfunction prevalence, time of onset and association with risk factors in 300 consecutive patients with acute chest pain and angiographically documented coronary artery disease. Eur Urol 2003;44:360-364.
    • (2003) Eur Urol , vol.44 , pp. 360-364
    • Montorsi, F.1    Briganti, A.2    Salonia, A.3    Rigatti, P.4    Margonato, A.5    Macchi, A.6    Galli, S.7    Ravagnani, P.M.8    Montorsi, P.9
  • 9
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study
    • Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994;151:54-61. (Pubitemid 24046934)
    • (1994) Journal of Urology , vol.151 , Issue.1 , pp. 54-61
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3    Krane, R.J.4    McKinlay, J.B.5
  • 11
    • 0026032652 scopus 로고
    • Shear stress-induced release of nitric oxide from endothelial cells grown on beads
    • Buga GM, Gold ME, Fukuto JM, Ignarro LJ. Shear stress-induced release of nitric oxide from endothelial cells grown on beads. Hypertension 1991;17:187-193.
    • (1991) Hypertension , vol.17 , pp. 187-193
    • Buga, G.M.1    Gold, M.E.2    Fukuto, J.M.3    Ignarro, L.J.4
  • 14
    • 0038755650 scopus 로고    scopus 로고
    • Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase
    • DOI 10.1161/01.CIR.0000074229.93804.5C
    • Hambrecht R, Adams V, Erbs S, Linke A, Krankel N, Shu Y, Baither Y, Gielen S, Thiele H, Gummert JF, Mohr FW, Schuler G. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 2003;107:3152-3158. (Pubitemid 36793084)
    • (2003) Circulation , vol.107 , Issue.25 , pp. 3152-3158
    • Hambrecht, R.1    Adams, V.2    Erbs, S.3    Linke, A.4    Krankel, N.5    Shu, Y.6    Baither, Y.7    Gielen, S.8    Thiele, H.9    Gummert, J.F.10    Mohr, F.W.11    Schuler, G.12
  • 16
    • 33749538569 scopus 로고    scopus 로고
    • Exercise training improves insulin-induced and insulin-like growth factor-1-induced vasorelaxation in rat aortas
    • Yang AL, Su CT, Lin KL, Chao JI, You HP, Lee SD. Exercise training improves insulin-induced and insulin-like growth factor-1-induced vasorelaxation in rat aortas. Life Sci 2006;79:2017-2021.
    • (2006) Life Sci , vol.79 , pp. 2017-2021
    • Yang, A.L.1    Su, C.T.2    Lin, K.L.3    Chao, J.I.4    You, H.P.5    Lee, S.D.6
  • 17
    • 0041700224 scopus 로고    scopus 로고
    • Sexual function in men older than 50 years of age: Results from the health professionals follow-up study
    • Bacon CG, Mittleman MA, Kawachi I, Giovannucci E, Glasser DB, Rimm EB. Sexual function in men older than 50 years of age: results from the health professionals follow-up study. Ann Int Med 2003;139: 161-168.
    • (2003) Ann Int Med , vol.139 , pp. 161-168
    • Bacon, C.G.1    Mittleman, M.A.2    Kawachi, I.3    Giovannucci, E.4    Glasser, D.B.5    Rimm, E.B.6
  • 18
    • 33846578156 scopus 로고    scopus 로고
    • Prevalence and Risk Factors for Erectile Dysfunction in the US
    • DOI 10.1016/j.amjmed.2006.06.010, PII S0002934306006899
    • Selvin E, Burnett AL, Platz EA. Prevalence and risk factors for erectile dysfunction in the US. Am J Med 2007;120:151-157. (Pubitemid 46175775)
    • (2007) American Journal of Medicine , vol.120 , Issue.2 , pp. 151-157
    • Selvin, E.1    Burnett, A.L.2    Platz, E.A.3
  • 19
    • 0036522513 scopus 로고    scopus 로고
    • Prevalence and correlates of erectile dysfunction in Turkey: A population-based study
    • DOI 10.1016/S0302-2838(02)00027-1, PII S0302283802000271
    • Akkus E, Kadioglu A, Esen A, Doran S, Ergen A, Anafarta K, Hattat H; Turkish Erectile Dysfunction Prevalence Study Group. Prevalence and correlates of erectile dysfunction in Turkey: a population-based study. Eur Urol 2002;41:298-304. (Pubitemid 35303429)
    • (2002) European Urology , vol.41 , Issue.3 , pp. 298-304
    • Akkus, E.1    Kadioglu, A.2    Esen, A.3    Doran, S.4    Ergen, A.5    Anafarta, K.6    Hattat, H.7
  • 20
    • 0033941058 scopus 로고    scopus 로고
    • Modifiable risk factors and erectile dysfunction: Can lifestyle changes modify risk?
    • DOI 10.1016/S0090-4295(00)00614-2, PII S0090429500006142
    • Derby CA, Mohr BA, Goldstein I, Feldman HA, Johannes CB, McKinlay JB. Modifiable risk factors and erectile dysfunction: can lifestyle changes modify risk? Urology 2000;56:302-306. (Pubitemid 30495587)
    • (2000) Urology , vol.56 , Issue.2 , pp. 302-306
    • Derby, C.A.1    Mohr, B.A.2    Goldstein, I.3    Feldman, H.A.4    Johannes, C.B.5    McKinlay, J.B.6
  • 23
    • 43749101797 scopus 로고    scopus 로고
    • Erectile Dysfunction as a Predictor of Cardiovascular Events and Death in Diabetic Patients With Angiographically Proven Asymptomatic Coronary Artery Disease. A Potential Protective Role for Statins and 5-Phosphodiesterase Inhibitors
    • DOI 10.1016/j.jacc.2007.10.069, PII S0735109708009480
    • Gazzaruso C, Solerte SB, Pujia A, Coppola A, Vezzoli M, Salvucci F, Valenti, C, Giustina A, Garzaniti A. Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease. A potential role for statins and 5-phosphodiesterase inhibitors. J Am Coll Cardiol 2008;51:2040-2044. (Pubitemid 351689055)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.21 , pp. 2040-2044
    • Gazzaruso, C.1    Solerte, S.B.2    Pujia, A.3    Coppola, A.4    Vezzoli, M.5    Salvucci, F.6    Valenti, C.7    Giustina, A.8    Garzaniti, A.9
  • 26
    • 0037069363 scopus 로고    scopus 로고
    • Effect of diet and exercise intervention on blood pressure, insulin, oxidative stress, and nitric oxide availability
    • DOI 10.1161/01.CIR.0000040584.91836.0D
    • Roberts CK, Nosratola D, Vaziri MD, Barnard J. Effect of diet and exercise intervention on blood pressure, insulin, oxidative stress, and nitric oxide availability. Circulation 2002;106:2530-2532. (Pubitemid 35340686)
    • (2002) Circulation , vol.106 , Issue.20 , pp. 2530-2532
    • Roberts, C.K.1    Vaziri, N.D.2    Barnard, R.J.3
  • 28
    • 77950197562 scopus 로고    scopus 로고
    • Erectile dysfunction predicts cardiovascular events in high-risk patients receiving telmisartan, ramipril, or both: The Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE Intolerant Subjects with Cardiovascular Disease (ONTARGET/TRANSCEND) trials
    • Bohm M, Baumhakel M, Teo K, Sleight P, Probstfield J, Gao P. Erectile dysfunction predicts cardiovascular events in high-risk patients receiving telmisartan, ramipril, or both: The Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE Intolerant Subjects With Cardiovascular Disease (ONTARGET/TRANSCEND) trials. Circulation 2010;121:1439-1446.
    • (2010) Circulation , vol.121 , pp. 1439-1446
    • Bohm, M.1    Baumhakel, M.2    Teo, K.3    Sleight, P.4    Probstfield, J.5    Gao, P.6
  • 29
    • 0035142782 scopus 로고    scopus 로고
    • Sexual activity in hypertensive men treated with valsartan or carvedilol: A crossover study
    • DOI 10.1016/S0895-7061(00)01214-0, PII S0895706100012140
    • Fogari R, Zoppi A, Poletti L, Marasi G, Mugellini A, Corradi L. Sexual activity in hypertensive men treated with valsartan or carvedilol: a crossover study. Am J Hypertens 2001; 14:27-31. (Pubitemid 32105914)
    • (2001) American Journal of Hypertension , vol.14 , Issue.1 , pp. 27-31
    • Fogari, R.1    Zoppi, A.2    Poletti, L.3    Marasi, G.4    Mugellini, A.5    Corradi, L.6
  • 30
    • 51949092574 scopus 로고    scopus 로고
    • Effect of Irbesartan on erectile function in patients with hypertension and metabolic syndrome
    • DO-IT Investigators
    • Baumhakel M, Schlimmer N, Bohm M; DO-IT Investigators. Effect of Irbesartan on erectile function in patients with hypertension and metabolic syndrome. Int J Impot Res 2008;20:493-500.
    • (2008) Int J Impot Res , vol.20 , pp. 493-500
    • Baumhakel, M.1    Schlimmer, N.2    Bohm, M.3
  • 32
    • 0037137299 scopus 로고    scopus 로고
    • Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease
    • DOI 10.1161/01.CIR.0000038493.65177.94
    • Kris-Etherton PM, Harris WS, Appel LJ; American Heart Association Nutrition Committee. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-2757. (Pubitemid 35364932)
    • (2002) Circulation , vol.106 , Issue.21 , pp. 2747-2757
    • Kris-Etherton, P.M.1    Harris, W.S.2    Appel, L.J.3
  • 35
    • 33746795022 scopus 로고    scopus 로고
    • Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide
    • DOI 10.1016/j.niox.2006.03.001, PII S1089860306000371
    • Ignarro LJ, Byrns RE, Sumi D, de Nigris F, Napoli C. Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biologic actions of nitric oxide. Nitric Oxide 2006;15:93-102. (Pubitemid 44175887)
    • (2006) Nitric Oxide - Biology and Chemistry , vol.15 , Issue.2 , pp. 93-102
    • Ignarro, L.J.1    Byrns, R.E.2    Sumi, D.3    De Nigris, F.4    Napoli, C.5
  • 36
    • 1442274617 scopus 로고    scopus 로고
    • Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans
    • DOI 10.1097/00004872-200312000-00016
    • Fisher ND, Hughes M, Gerhard-Herman M, Hollenberg NK. Flavanolrich cocoa induces nitric-oxide-dependent vasodilation in healthy humans. J Hypertens 2003;21:2281-2286. (Pubitemid 38293567)
    • (2003) Journal of Hypertension , vol.21 , Issue.12 , pp. 2281-2286
    • Fisher, N.D.L.1    Hughes, M.2    Gerhard-Herman, M.3    Hollenberg, N.K.4
  • 37
    • 64949105864 scopus 로고    scopus 로고
    • Vascular reactivity is affected by dietary consumption of wild blueberries in the Sprague-Dawley rat
    • Kalea AZ, Clark K, Schuschke DA, Klimis-Zacas DJ. Vascular reactivity is affected by dietary consumption of wild blueberries in the Sprague-Dawley rat. J Med Food 2009;12:21-28.
    • (2009) J Med Food , vol.12 , pp. 21-28
    • Kalea, A.Z.1    Clark, K.2    Schuschke, D.A.3    Klimis-Zacas, D.J.4
  • 38
    • 33747061585 scopus 로고    scopus 로고
    • Tea flavanols inhibit angiotensin-converting enzyme activity and increase nitric oxide production in human endothelial cells
    • DOI 10.1211/jpp.58.8.0016
    • Persson IA, Josefsson M, Persson K, Andersson RG. Tea flavanols inhibit angiotensin-converting enzyme activity and increase nitric oxide production in human endothelial cells. J Pharm Pharmacol 2006; 58:1139-1144. (Pubitemid 44213648)
    • (2006) Journal of Pharmacy and Pharmacology , vol.58 , Issue.8 , pp. 1139-1144
    • Persson, I.A.-L.1    Josefsson, M.2    Persson, K.3    Andersson, R.G.G.4
  • 39
    • 0037419818 scopus 로고    scopus 로고
    • Red wine increases the expression of human endothelial nitric oxide synthase: A mechanism that may contribute to its beneficial cardiovascular effects
    • DOI 10.1016/S0735-1097(02)02826-7
    • Wallerath T, Poleo D, Li H, Forstermann U. Red wine increases the expression of human endothelial nitric oxide synthase: a mechanism that may contribute to its beneficial cardiovascular effects. J Am Coll Cardiol 2003;41:471-478. (Pubitemid 36164505)
    • (2003) Journal of the American College of Cardiology , vol.41 , Issue.3 , pp. 471-478
    • Wallerath, T.1    Poleo, D.2    Li, H.3    Forstermann, U.4
  • 40
    • 68949083483 scopus 로고    scopus 로고
    • Chocolate consumption and mortality following a first acute myocardial infarction: The Stockholm Heart Epidemiology Program
    • Janszky I, Mukamal KJ, Ljung R, Ahnve S, Ahlbom A, Hallkvist J. Chocolate consumption and mortality following a first acute myocardial infarction: the Stockholm Heart Epidemiology Program. J Intern Med 2009;266:248-257.
    • (2009) J Intern Med , vol.266 , pp. 248-257
    • Janszky, I.1    Mukamal, K.J.2    Ljung, R.3    Ahnve, S.4    Ahlbom, A.5    Hallkvist, J.6
  • 41
    • 0037188559 scopus 로고    scopus 로고
    • Tea consumption and mortality after acute myocardial infarction
    • DOI 10.1161/01.CIR.0000017201.88994.F7
    • Mukamal KJ, Maclure M, Muller JE, Sherwood JB, Mittleman MA. Tea consumption and mortality after acute myocardial infarction. Circulation 2002;105:2476-2481. (Pubitemid 34568967)
    • (2002) Circulation , vol.105 , Issue.21 , pp. 2476-2481
    • Mukamal, K.J.1    Maclure, M.2    Muller, J.E.3    Sherwood, J.B.4    Mittleman, M.A.5
  • 42
    • 47249091864 scopus 로고    scopus 로고
    • Acute dark chocolate and cocoa ingestion and endothelial function: A randomized controlled crossover trial
    • Faridi Z, Njike VY, Dutta S, Ali A, Katz DL. Acute dark chocolate and cocoa ingestion and endothelial function: a randomized controlled crossover trial. Am J Clin Nutr 2008;88:58-63. (Pubitemid 351988683)
    • (2008) American Journal of Clinical Nutrition , vol.88 , Issue.1 , pp. 58-63
    • Faridi, Z.1    Njike, V.Y.2    Dutta, S.3    Ali, A.4    Katz, D.L.5
  • 43
    • 78650211599 scopus 로고    scopus 로고
    • A multifaceted approach to maximize erectile function and vascular health
    • Meldrum DR, Gambone JC, Morris MA, Ignarro LJ. A multifaceted approach to maximize erectile function and vascular health. Fertil Steril 2010;94:2514-2520.
    • (2010) Fertil Steril , vol.94 , pp. 2514-2520
    • Meldrum, D.R.1    Gambone, J.C.2    Morris, M.A.3    Ignarro, L.J.4
  • 45
    • 77950409922 scopus 로고    scopus 로고
    • Folate intake and bowel cancer risk
    • Mathers JC. Folate intake and bowel cancer risk. Genes Nutr 2009;4: 173-178.
    • (2009) Genes Nutr , vol.4 , pp. 173-178
    • Mathers, J.C.1
  • 46
    • 0025172694 scopus 로고
    • 2+ concentrations in the production of endothelial nitric oxide and the control of vascular tone
    • Lopez-Jaramillo P, Gonzalez MC, Palmer RMJ, Moncada S. The crucial role of physiologic Ca2+ concentrations in the production of endothelial nitric oxide and the control of vascular tone. Br J Pharmacol 1990;101:489-493. (Pubitemid 20292911)
    • (1990) British Journal of Pharmacology , vol.101 , Issue.2 , pp. 489-493
    • Lopez-Jaramillo, P.1    Gonzalez, M.C.2    Palmer, R.M.J.3    Moncada, S.4
  • 48
    • 34547736129 scopus 로고    scopus 로고
    • Risk factors for prostate cancer incidence and progression in the health professionals follow-up study
    • DOI 10.1002/ijc.22788
    • Giovannucci E, Liu Y, Platz EA, Stampfer MJ, Willett WC. Risk factors for prostatic cancer incidence and progression in the health professionals follow-up study. Int J Cancer 2007;121:1571-1578. (Pubitemid 47328718)
    • (2007) International Journal of Cancer , vol.121 , Issue.7 , pp. 1571-1578
    • Giovannucci, E.1    Liu, Y.2    Platz, E.A.3    Stampfer, M.J.4    Willett, W.C.5
  • 49
    • 77955402131 scopus 로고    scopus 로고
    • Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: Meta-analysis
    • Bolland MJ, Avenell A, Baron JA, Grey A, Maclennan GS, Gamble GD. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ 2010;341:c3691.
    • (2010) BMJ , vol.341
    • Bolland, M.J.1    Avenell, A.2    Baron, J.A.3    Grey, A.4    Maclennan, G.S.5    Gamble, G.D.6
  • 50
    • 0034682912 scopus 로고    scopus 로고
    • Antioxidants and the bioactivity of endothelium-derived nitric oxide
    • DOI 10.1016/S0008-6363(00)00103-6, PII S0008636300001036
    • Tomasian D, Keaney JF, Vita JA. Antioxidants and the bioactivity of endothelium-derived nitric oxide. Cardiovasc Res 2000;47:426-435. (Pubitemid 30646065)
    • (2000) Cardiovascular Research , vol.47 , Issue.3 , pp. 426-435
    • Tomasian, D.1    Keaney Jr., J.F.2    Vita, J.A.3
  • 55
    • 0023446425 scopus 로고
    • The anti-aggregating properties of vascular endothelium: Interactions between prostacycline and nitric oxide
    • Radomski MW, Palmer RMJ, Moncada S. The anti-aggregating properties of vascular endothelium: interactions between prostacycline and nitric oxide. Br J Pharmacol 1987;92:639-646.
    • (1987) Br J Pharmacol , vol.92 , pp. 639-646
    • Radomski, M.W.1    Palmer, R.M.J.2    Moncada, S.3
  • 56
  • 57
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RMJ, Ferrige AG, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988;333:664-666.
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 58
    • 0025018196 scopus 로고
    • The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: Cultured endothelial cells recycle Lcitrulline to L-arginine
    • Hecker M, Sessa WC, Harris J, Anggard EE, Vane JR. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: Cultured endothelial cells recycle Lcitrulline to L-arginine. Proc Natl Acad Sci U S A 1990;87:8612-8616.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 8612-8616
    • Hecker, M.1    Sessa, W.C.2    Harris, J.3    Anggard, E.E.4    Vane, J.R.5
  • 60
    • 0342980238 scopus 로고    scopus 로고
    • Effectiveness of oral L-arginine in first-line treatment of erectile dysfunction in a controlled crossover study
    • Klotz T, Mathers MJ, Braun M, Bloch W, Engelmann U. Effectiveness of oral L-arginine in first-line treatment of erectile dysfunction in a controlled crossover study. Urol Int 1999;63:220-223. (Pubitemid 30072009)
    • (1999) Urologia Internationalis , vol.63 , Issue.4 , pp. 220-223
    • Klotz, T.1    Mathers, M.J.2    Braun, M.3    Bloch, W.4    Engelmann, U.5
  • 61
    • 0033035004 scopus 로고    scopus 로고
    • Effect of oral administration of high-dose nitric oxide donor L-arginine in men with organic erectile dysfunction: Results of a double-blind, randomized, placebo-controlled study
    • DOI 10.1046/j.1464-410X.1999.00906.x
    • Chen J, Wollman Y, Chernichovsky T, Iaina A, Sofer M, Matzkin H. Effect of oral administration of high-dose nitric oxide donor L-arginine in men with organic erectile dysfunction: results of a double-blind, randomized, placebo-controlled study. BJU Int 1999;83:269-273. (Pubitemid 29151525)
    • (1999) BJU International , vol.83 , Issue.3 , pp. 269-273
    • Chen, J.1    Wollman, Y.2    Chernichovsky, T.3    Iaina, A.4    Sofer, M.5    Matzkin, H.6
  • 62
    • 0028386686 scopus 로고
    • Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction
    • Zorgniotti AW, Lizza EF. Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction. Int J Impot Res 1994; 6:33-35.
    • (1994) Int J Impot Res , vol.6 , pp. 33-35
    • Zorgniotti, A.W.1    Lizza, E.F.2
  • 64
    • 34247093334 scopus 로고    scopus 로고
    • Nitric oxide and the vascular endothelium
    • Moncada S, Higgs EA. Nitric oxide and the vascular endothelium. Handb Exp Pharmacol 2006;176:213-254.
    • (2006) Handb Exp Pharmacol , vol.176 , pp. 213-254
    • Moncada, S.1    Higgs, E.A.2
  • 66
    • 42449111660 scopus 로고    scopus 로고
    • Testosterone for the aging male; current evidence and recommended practice
    • Stanworth RD, Jones TH. Testosterone for the aging male: current evidence and recommended practice. Clin Interv Aging 2008;3:25-44. (Pubitemid 351559801)
    • (2008) Clinical Interventions in Aging , vol.3 , Issue.1 , pp. 25-44
    • Stanworth, R.D.1    Jones, T.H.2
  • 67
    • 37849004379 scopus 로고    scopus 로고
    • Low testosterone level is an independent determinant of endothelial dysfunction in men
    • Akishita M, Hashimoto M, Ohike Y, Ogawa S, Iijima K, Eto M, Ouchi Y. Low testosterone level is an independent determinant of endothelial dysfunction in men. Hypertens Res 2007;30:1029-1034.
    • (2007) Hypertens Res , vol.30 , pp. 1029-1034
    • Akishita, M.1    Hashimoto, M.2    Ohike, Y.3    Ogawa, S.4    Iijima, K.5    Eto, M.6    Ouchi, Y.7
  • 68
    • 0034040591 scopus 로고    scopus 로고
    • Erectile dysfunction and coronary risk factors: Prospective results from the Massachusetts Male Aging Study
    • DOI 10.1006/pmed.2000.0643
    • Feldman HA, Johannes CB, Derby CA, Kleinman KP, Mohr BA, Araujo AB, McKinlay JB. Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study. Prev Med 2000;30:328-338. (Pubitemid 30211093)
    • (2000) Preventive Medicine , vol.30 , Issue.4 , pp. 328-338
    • Feldman, H.A.1    Johannes, C.B.2    Derby, C.A.3    Kleinman, K.P.4    Mohr, B.A.5    Araujo, A.B.6    McKinlay, J.B.7
  • 69
    • 66949153972 scopus 로고    scopus 로고
    • Superoxide-mediated inactivation of nitric oxide and peroxinitrite formation by tobacco smoke in vascular endothelium: Studies in cultured cells and smokers
    • Peluffo G, Calcerrada P, Piacenza L, Pizzano N, Radi F. Superoxide-mediated inactivation of nitric oxide and peroxinitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers. Am J Physiol Heart Circ Physiol 2009;96:H1781-H1792.
    • (2009) Am J Physiol Heart Circ Physiol , vol.96
    • Peluffo, G.1    Calcerrada, P.2    Piacenza, L.3    Pizzano, N.4    Radi, F.5
  • 70
    • 34347385066 scopus 로고    scopus 로고
    • Alcohol consumption and erectile dysfunction: Meta-analysis of population-based studies
    • DOI 10.1038/sj.ijir.3901556, PII 3901556
    • Cheng JYW, Ng EML, Chen RL, Ko JSN. Alcohol consumption and erectile dysfunction: meta-analysis of population-based studies. Int J Impot Res 2007;19:343-352. (Pubitemid 47026091)
    • (2007) International Journal of Impotence Research , vol.19 , Issue.4 , pp. 343-352
    • Cheng, J.Y.W.1    Ng, E.M.L.2    Chen, R.Y.L.3    Ko, J.S.N.4
  • 72
    • 57849153948 scopus 로고    scopus 로고
    • Effects of ethanol treatment on the neurogenic and endothelium-dependent relaxation of corpus cavernosum smooth muscle in the mouse
    • Aydinoglu F, Yilmaz SN, Coskun B, Daglioglu N. Ogulener N. Effects of ethanol treatment on the neurogenic and endothelium-dependent relaxation of corpus cavernosum smooth muscle in the mouse. Pharmacol Rep 2008;60:725-734.
    • (2008) Pharmacol Rep , vol.60 , pp. 725-734
    • Aydinoglu, F.1    Yilmaz, S.N.2    Coskun, B.3    Daglioglu, N.4    Ogulener, N.5
  • 73
    • 45849140499 scopus 로고    scopus 로고
    • Regular intercourse protects against erectile dysfunction: Tampere Aging Male Urologic Study
    • Koskimaki J, Shiri R, Tammela T, Hakkinen J, Hakama M, Auvinen A. Regular intercourse protects against erectile dysfunction: Tampere Aging Male Urologic Study. Am J Med 2008;121:592-596.
    • (2008) Am J Med , vol.121 , pp. 592-596
    • Koskimaki, J.1    Shiri, R.2    Tammela, T.3    Hakkinen, J.4    Hakama, M.5    Auvinen, A.6
  • 74
    • 33750689471 scopus 로고    scopus 로고
    • Nitric oxide and cyclic GMP in cell signaling and drug development
    • DOI 10.1056/NEJMsa063904
    • Murad F. Shattuck Lecture: nitric oxide and cyclic GMP in cell signaling and drug development. N Engl J Med 2006;395:2003-2011. (Pubitemid 44708019)
    • (2006) New England Journal of Medicine , vol.355 , Issue.19 , pp. 2003-2011
    • Murad, F.1
  • 75
    • 77949656033 scopus 로고    scopus 로고
    • Assessment of the acute effects of tadalafil on the cardiovascular system based on examination of serum oxidative status and paraoxonase activity in men with erectile dysfunction: A preliminary study
    • Verit A, Savas M, Ciftci H, Aksoy N, Taskin A, Topal U. Assessment of the acute effects of tadalafil on the cardiovascular system based on examination of serum oxidative status and paraoxonase activity in men with erectile dysfunction: a preliminary study. Int J Impot Res 2010; 22:115-119.
    • (2010) Int J Impot Res , vol.22 , pp. 115-119
    • Verit, A.1    Savas, M.2    Ciftci, H.3    Aksoy, N.4    Taskin, A.5    Topal, U.6
  • 78
    • 12344288164 scopus 로고    scopus 로고
    • Chronic treatment with Tadalafil improves endothelial function in men with increased cardiovascular risk
    • DOI 10.1016/j.eururo.2004.10.002, PII S0302283804005093
    • Rosano GMC, Aversa A, Vitale C, Fabbri A, Fini M, Spera G. Chronic treatment with tadalafil improves endothelial function in men with increased cardiovascular risk. Eur Urol 2005;47:214-222. (Pubitemid 40126979)
    • (2005) European Urology , vol.47 , Issue.2 , pp. 214-222
    • Rosano, G.M.C.1    Aversa, A.2    Vitale, C.3    Fabbri, A.4    Fini, M.5    Spera, G.6
  • 79
    • 0025100874 scopus 로고
    • Release of endothelin from the porcine aorta. Inhibition of endothelium-derived nitric oxide
    • Boulanger C, Luscher TF. Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. J Clin Invest 1990;85:587-590. (Pubitemid 20070070)
    • (1990) Journal of Clinical Investigation , vol.85 , Issue.2 , pp. 587-590
    • Boulanger, C.1    Luscher, T.F.2
  • 81
    • 33750579081 scopus 로고    scopus 로고
    • Effect of regular phosphodiesterase type 5 inhibition in hypertension
    • DOI 10.1161/01.HYP.0000239816.13007.c9, PII 0000426820061000000021
    • Oliver JJ, Melville VP, Webb DJ. Effect of regular phosphodiesterase type 5 inhibition in hypertension. Hypertension 2006;48:622-627. (Pubitemid 44843865)
    • (2006) Hypertension , vol.48 , Issue.4 , pp. 622-627
    • Oliver, J.J.1    Melville, V.P.2    Webb, D.J.3
  • 83
    • 33847083496 scopus 로고    scopus 로고
    • Effect of exercise on blood pressure control in hypertensive patients
    • Fagard RH, Cornelissen VA. Effect of exercise on blood pressure control in hypertensive patients. Eur J Cardiovasc Prev Rehabil 2007; 14:12-17.
    • (2007) Eur J Cardiovasc Prev Rehabil , vol.14 , pp. 12-17
    • Fagard, R.H.1    Cornelissen, V.A.2
  • 84
    • 67651218924 scopus 로고    scopus 로고
    • Diet and lifestyle factors associated with incident hypertension in women
    • Forman JP, Stampfer MJ, Curhan GC. Diet and lifestyle factors associated with incident hypertension in women. JAMA 2009;302:401-411.
    • (2009) JAMA , vol.302 , pp. 401-411
    • Forman, J.P.1    Stampfer, M.J.2    Curhan, G.C.3
  • 87
    • 80052749004 scopus 로고    scopus 로고
    • Effect of the Mediterranean diet with and without weight loss on cardiovascular risk factors in men with the metabolic syndrome
    • In press
    • Richard C, Couture P, Desroches S, Charest A, Lamarche B. Effect of the Mediterranean diet with and without weight loss on cardiovascular risk factors in men with the metabolic syndrome. Nutr Metab Cardiovasc Dis. In press.
    • Nutr Metab Cardiovasc Dis
    • Richard, C.1    Couture, P.2    Desroches, S.3    Charest, A.4    Lamarche, B.5
  • 88
    • 0025308724 scopus 로고
    • Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension
    • Bonaa KH, Bjerve KS, Straume B, Gram IT, Thelle D. Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. N Engl J Med 1990;322:795-801.
    • (1990) N Engl J Med , vol.322 , pp. 795-801
    • Bonaa, K.H.1    Bjerve, K.S.2    Straume, B.3    Gram, I.T.4    Thelle, D.5
  • 90
    • 33644599022 scopus 로고    scopus 로고
    • Cocoa intake, blood pressure, and cardiac mortality. The Zutphen Elderly Study
    • Buijsse B, Feskens EJM, Kok FJ, Kromhout D. Cocoa intake, blood pressure, and cardiac mortality. The Zutphen Elderly Study. Arch Intern Med 2006;166:411-417.
    • (2006) Arch Intern Med , vol.166 , pp. 411-417
    • Buijsse, B.1    Feskens, E.J.M.2    Kok, F.J.3    Kromhout, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.