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Volumn 83, Issue 3, 1999, Pages 269-273

Effect of oral administration of high-dose nitric oxide donor L-arginine in men with organic erectile dysfunction: Results of a double-blind, randomized, placebo-controlled study

Author keywords

Erectile dysfunction; L arginine; Nitric oxide donor; Oral treatment

Indexed keywords

ARGININE; NITRATE; NITRIC OXIDE DONOR; NITRITE;

EID: 0033035004     PISSN: 14644096     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-410X.1999.00906.x     Document Type: Article
Times cited : (148)

References (22)
  • 1
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • 1 Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333: 664-6
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.J.1    Ashton, D.S.2    Moncada, S.3
  • 3
    • 0026353632 scopus 로고
    • Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission
    • 3 Rajfer J, Aronson WJ, Bush PA, Dorey FJ, Ignarro LJ. Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission. N Engl J Med 1992; 326: 90-4
    • (1992) N Engl J Med , vol.326 , pp. 90-94
    • Rajfer, J.1    Aronson, W.J.2    Bush, P.A.3    Dorey, F.J.4    Ignarro, L.J.5
  • 4
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • 4 Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524-6
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 5
    • 0027366315 scopus 로고
    • Nitric oxide synthase: A new diagnostic tool for neurogenic impotence
    • 5 Brock G, Nunes L, Padma-Nathan H, Boyd S, Lue T. Nitric oxide synthase: a new diagnostic tool for neurogenic impotence. Urology 1993; 42: 412-7
    • (1993) Urology , vol.42 , pp. 412-417
    • Brock, G.1    Nunes, L.2    Padma-Nathan, H.3    Boyd, S.4    Lue, T.5
  • 6
    • 0031060411 scopus 로고    scopus 로고
    • Nitric oxide in the penis: Physiology and pathology
    • 6 Burnett AL. Nitric oxide in the penis: physiology and pathology. J Urol 1997; 157: 320-4
    • (1997) J Urol , vol.157 , pp. 320-324
    • Burnett, A.L.1
  • 7
    • 0024559857 scopus 로고
    • Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence
    • 7 Saez de Tejada I, Goldstein I, Azadzoi K, Krane RJ, Cohen RA. Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. N Engl J Med 1989; 320: 1025-30
    • (1989) N Engl J Med , vol.320 , pp. 1025-1030
    • Saez De Tejada, I.1    Goldstein, I.2    Azadzoi, K.3    Krane, R.J.4    Cohen, R.A.5
  • 8
    • 0025733506 scopus 로고
    • A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle
    • 8 Kim N, Azadzoi KM, Goldstein I, Saenz de Tejada I. A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle. J Clin Invest 1991; 88: 112-8
    • (1991) J Clin Invest , vol.88 , pp. 112-118
    • Kim, N.1    Azadzoi, K.M.2    Goldstein, I.3    Saenz De Tejada, I.4
  • 9
    • 0027197417 scopus 로고
    • Intracavernous application of SIN-1 in rabbit and man: Functional and toxicological results
    • 9 Meyer MF, Tahar A, Krah H et al. Intracavernous application of SIN-1 in rabbit and man: functional and toxicological results. Ann Urol 1993; 27: 179-82
    • (1993) Ann Urol , vol.27 , pp. 179-182
    • Meyer, M.F.1    Tahar, A.2    Krah, H.3
  • 10
    • 0028598574 scopus 로고
    • Role of the nitric oxide donor linsidomine chlorohydrate (SIN-1) in the diagnosis and treatment of erectile dysfunction
    • 10 Truss MC, Becker AJ, Djamilian MH, Stief CG, Jonas U. Role of the nitric oxide donor linsidomine chlorohydrate (SIN-1) in the diagnosis and treatment of erectile dysfunction. Urology 1994; 44: 553-6
    • (1994) Urology , vol.44 , pp. 553-556
    • Truss, M.C.1    Becker, A.J.2    Djamilian, M.H.3    Stief, C.G.4    Jonas, U.5
  • 11
    • 0026595406 scopus 로고
    • Preliminary results with the nitric oxide donor linsidomine chlorohydrate in the treatment of human erectile dysfunction
    • 11 Stief CG, Holmquist F, Djamilian M, Krah H, Andersson KE, Jonas U. Preliminary results with the nitric oxide donor linsidomine chlorohydrate in the treatment of human erectile dysfunction. J Urol 1992; 148: 1437-40
    • (1992) J Urol , vol.148 , pp. 1437-1440
    • Stief, C.G.1    Holmquist, F.2    Djamilian, M.3    Krah, H.4    Andersson, K.E.5    Jonas, U.6
  • 12
    • 0027488635 scopus 로고
    • Effect of nitric oxide-donor, linsidomine chlorohydrate, the treatment of human erectile dysfunction caused by venous leakage
    • 12 Wegner HEH, Knispel HH. Effect of nitric oxide-donor, linsidomine chlorohydrate, the treatment of human erectile dysfunction caused by venous leakage. Urology 1993; 42: 409-11
    • (1993) Urology , vol.42 , pp. 409-411
    • Wegner, H.E.H.1    Knispel, H.H.2
  • 13
    • 0030742021 scopus 로고    scopus 로고
    • Effects of long-term oral administration of l-arginine on the rat erectile response
    • 13 Moody JA, Vernet D, Laidlaw S, Rajfer J, Gonzalez-Cadavid NF. Effects of long-term oral administration of l-arginine on the rat erectile response. J Urol 1997; 158: 942-7
    • (1997) J Urol , vol.158 , pp. 942-947
    • Moody, J.A.1    Vernet, D.2    Laidlaw, S.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 14
    • 0028386686 scopus 로고
    • Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction
    • 14 Zorgniotti AW, Lizza EF. Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction. Int J Impot Res 1994; 6: 33-5
    • (1994) Int J Impot Res , vol.6 , pp. 33-35
    • Zorgniotti, A.W.1    Lizza, E.F.2
  • 15
    • 0028838399 scopus 로고
    • A brief male sexual function inventory for urology
    • 15 O'Leary ME, Fowler FJ and Lenderking WR et al. A brief male sexual function inventory for urology. Urology 1995; 46: 697-706
    • (1995) Urology , vol.46 , pp. 697-706
    • O'Leary, M.E.1    Fowler, F.J.2    Lenderking, W.R.3
  • 16
    • 0028846538 scopus 로고
    • Improvement of cardiac performance by intravenous infusion of l-arginine in patients with moderate congestive heart failure
    • 16 Koifman B, Wollman Y, Bogomolny N et al. Improvement of cardiac performance by intravenous infusion of l-arginine in patients with moderate congestive heart failure. J Am Coll Cardiol 1995; 26: 1251-6
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1251-1256
    • Koifman, B.1    Wollman, Y.2    Bogomolny, N.3
  • 18
    • 0343581280 scopus 로고    scopus 로고
    • Is high-dose Yohimbine hydrochloride effective in the treatment of mixed-type impotence? A prospective, randomized, controlled double-blind crossover study
    • 18 Kunelius P, Hakkinen J, Lukkarinen O. Is high-dose Yohimbine hydrochloride effective in the treatment of mixed-type impotence? A prospective, randomized, controlled double-blind crossover study. Urology 1997; 49: 441-4
    • (1997) Urology , vol.49 , pp. 441-444
    • Kunelius, P.1    Hakkinen, J.2    Lukkarinen, O.3
  • 19
    • 0030154874 scopus 로고    scopus 로고
    • Sildenafil: An orally active 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction
    • 19 Boolell M, Allen MJ, Ballard SA et al. Sildenafil: an orally active 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int J Impot Res 1996; 8: 47-52
    • (1996) Int J Impot Res , vol.8 , pp. 47-52
    • Boolell, M.1    Allen, M.J.2    Ballard, S.A.3
  • 20
    • 0032516296 scopus 로고    scopus 로고
    • Oral Sildenafil in the treatment of Erectile Dysfunction
    • 20 Goldstein I, Lue TF, Padma-Nathan H et al. Oral Sildenafil in the treatment of Erectile Dysfunction. N Engl J Med 1998; 338: 1397-404
    • (1998) N Engl J Med , vol.338 , pp. 1397-1404
    • Goldstein, I.1    Lue, T.F.2    Padma-Nathan, H.3
  • 21
    • 15844389652 scopus 로고    scopus 로고
    • Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults
    • 21 Clarkson P, Adams MR, Powe AJ et al. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults. J Clin Invest 1996; 97: 1989-93
    • (1996) J Clin Invest , vol.97 , pp. 1989-1993
    • Clarkson, P.1    Adams, M.R.2    Powe, A.J.3
  • 22
    • 0030829925 scopus 로고    scopus 로고
    • Effect of long-term oral L-arginine on the nitric oxide synthase pathway in the urine from patients with interstitial cystitis
    • 22 Wheeler MA, Smith SD, Saito N, Foster HE Jr, Weiss RM. Effect of long-term oral L-arginine on the nitric oxide synthase pathway in the urine from patients with interstitial cystitis. J Urol 1997; 158: 2045-50
    • (1997) J Urol , vol.158 , pp. 2045-2050
    • Wheeler, M.A.1    Smith, S.D.2    Saito, N.3    Foster H.E., Jr.4    Weiss, R.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.