Photoirradiation of dehydropyrrolizidine alkaloids-Formation of reactive oxygen species and induction of lipid peroxidation

Toxicology Letters

Volumn 205, Issue 3, 2011, Pages 302-309

  Zhao, Yuewei ^a   Xia, Qingsu ^a   Yin, Jun Jie ^b   Lin, Ge ^c   Fu, Peter P ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Dehydropyrrolizidine alkaloids; Lipid peroxidation; Photoirradiation; Reactive oxygen species; UVA light

Indexed keywords

DEHYDROHELIOTRINE; DEHYDROLASIOCARPINE; DEHYDRORETRONECINE; DEHYDRORETRORSINE; DEHYDRORIDDELLIINE; DEHYDROSENECIONINE; DEHYDROSENECIPHYLLINE; HELIOTRINE; LASIOCARPINE; METHANOL; MONOCROTALINE; MONOCROTALINE PYRROLE; OXYGEN; PYRROLIZIDINE ALKALOID; REACTIVE OXYGEN METABOLITE; RETRONECINE; RETRORSINE; RIDDELLINE; SENKIRKINE; SINGLET OXYGEN; SODIUM AZIDE; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENICITY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; IRRADIATION; LIPID PEROXIDATION; LIVER TOXICITY; OXIDATIVE STRESS; PHOTOSENSITIZATION; PRIORITY JOURNAL; RADIATION DOSE; SKIN CANCER; ULTRAVIOLET A RADIATION;

EID: 79960903323     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.06.020     Document Type: Article

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